{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,24]],"date-time":"2026-08-24T16:18:42Z","timestamp":1787588322965,"version":"build-2736575974"},"reference-count":16,"publisher":"Wiley","license":[{"start":{"date-parts":[[2020,5,6]],"date-time":"2020-05-06T00:00:00Z","timestamp":1588723200000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"name":"NEI Core Center","award":["P30 EY014801"],"award-info":[{"award-number":["P30 EY014801"]}]},{"DOI":"10.13039\/100006686","name":"University of Miami","doi-asserted-by":"publisher","award":["P30 EY014801"],"award-info":[{"award-number":["P30 EY014801"]}],"id":[{"id":"10.13039\/100006686","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Journal of Ophthalmology"],"published-print":{"date-parts":[[2020,5,6]]},"abstract":"\n Purpose<\/jats:italic>\n . To characterize the clinical features in young patients with angle closure and to determine the characteristics associated with acquired anterior segment abnormality following retinopathy of prematurity (ROP) treatment.\n Methods<\/jats:italic>\n . We performed two retrospective case-control series. In the first series, we identified consecutive young angle closure patients without prior surgeries, with and without a history of ROP treatment; in the second series we identified consecutive patients who underwent ROP treatment, without and without anterior segment changes.\n Results<\/jats:italic>\n . In the first series, 25 eyes of 14 consecutive angle closure patients were included: 19 eyes (11 patients, 78.6%) had a history of treated ROP, while 6 eyes (3 patients) belonged to full-term patients. The treated ROP eyes had significantly shallower anterior chambers (1.77\u2009\u00b1\u20090.17\u2009mm vs 2.72\u2009\u00b1\u20090.18\u2009mm,\n \n \n P<\/mml:mi>\n <<\/mml:mo>\n 0.0001<\/mml:mn>\n <\/mml:mrow>\n <\/mml:math>\n ) and thicker lenses (5.20\u2009\u00b1\u20090.54\u2009mm vs 3.98\u2009\u00b1\u20090.20\u2009mm,\n \n \n P<\/mml:mi>\n =<\/mml:mo>\n 0.0002<\/mml:mn>\n <\/mml:mrow>\n <\/mml:math>\n ) compared to the full-term controls. In the second series, 79 eyes of 40 patients were included, with median gestational age of 24.6 weeks. Acquired iridocorneal adhesion was noted in the eight eyes (10.1%) at a mean age of 4.7 years and was associated with prior zone 1 and plus disease (\n \n \n P<\/mml:mi>\n =<\/mml:mo>\n 0.0013<\/mml:mn>\n <\/mml:mrow>\n <\/mml:math>\n ), a history of initial intravitreal bevacizumab treatment (IVB,\n \n \n P<\/mml:mi>\n =<\/mml:mo>\n 0.0477<\/mml:mn>\n <\/mml:mrow>\n <\/mml:math>\n ) and a history of requiring additional IVB after initial treatment (\n \n \n P<\/mml:mi>\n =<\/mml:mo>\n 0.0337<\/mml:mn>\n <\/mml:mrow>\n <\/mml:math>\n ).\n Conclusions<\/jats:italic>\n . Many young angle closure patients may have a history of treated ROP and may present with the triad of increased lens thickness, microcornea, and angle closure.\n <\/jats:p>","DOI":"10.1155\/2020\/7510903","type":"journal-article","created":{"date-parts":[[2020,5,6]],"date-time":"2020-05-06T19:34:56Z","timestamp":1588793696000},"page":"1-7","source":"Crossref","is-referenced-by-count":9,"title":["Microcornea and Thickened Lens in Angle Closure following Nonsurgical Treatment of Retinopathy of Prematurity"],"prefix":"10.1155","volume":"2020","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-4827-5014","authenticated-orcid":true,"given":"Ta C.","family":"Chang","sequence":"first","affiliation":[{"name":"Bascom Palmer Eye Institute, Miami, FL, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kimberly D.","family":"Tran","sequence":"additional","affiliation":[{"name":"Asociaci\u00f3n para Evitar la Ceguera en M\u00e9xico, Mexico City, Mexico"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Linda A.","family":"Cernichiaro-Espinosa","sequence":"additional","affiliation":[{"name":"Sanford Eye Center, Sioux Falls, SD, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ella H.","family":"Leung","sequence":"additional","affiliation":[{"name":"Georgia Retina, Cartersville, GA, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alana L.","family":"Grajewski","sequence":"additional","affiliation":[{"name":"Bascom Palmer Eye Institute, Miami, FL, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Elizabeth A.","family":"Hodapp","sequence":"additional","affiliation":[{"name":"Bascom Palmer Eye Institute, Miami, FL, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4508-0492","authenticated-orcid":true,"given":"Mohamed F.","family":"Abou Shousha","sequence":"additional","affiliation":[{"name":"Bascom Palmer Eye Institute, Miami, FL, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Audina M.","family":"Berrocal","sequence":"additional","affiliation":[{"name":"Bascom Palmer Eye Institute, Miami, FL, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","reference":[{"key":"1","doi-asserted-by":"publisher","DOI":"10.3928\/01913913-20140521-04"},{"key":"2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jcrs.2004.01.014"},{"key":"3","first-page":"3","volume-title":"Section 1: definition, classification, differential diagnosis","year":"2013"},{"key":"4","doi-asserted-by":"publisher","DOI":"10.1016\/s0161-6420(79)35437-9"},{"key":"5","doi-asserted-by":"publisher","DOI":"10.1016\/s0161-6420(91)32172-9"},{"key":"6","doi-asserted-by":"publisher","DOI":"10.1007\/s00417-016-3307-0"},{"key":"7","doi-asserted-by":"publisher","DOI":"10.1001\/jamaophthalmol.2014.2772"},{"key":"8","doi-asserted-by":"publisher","DOI":"10.1016\/j.ophtha.2005.11.018"},{"key":"9","doi-asserted-by":"publisher","DOI":"10.1056\/nejmoa1007374"},{"key":"10","doi-asserted-by":"publisher","DOI":"10.1016\/j.ophtha.2014.12.017"},{"key":"11","doi-asserted-by":"publisher","DOI":"10.3109\/13816810903567604"},{"key":"12","doi-asserted-by":"publisher","DOI":"10.1007\/s00018-011-0780-9"},{"key":"13","doi-asserted-by":"publisher","DOI":"10.1002\/humu.22374"},{"issue":"20","key":"14","first-page":"790","volume":"12","year":"2014","journal-title":"Molecular Vision"},{"key":"15","doi-asserted-by":"publisher","DOI":"10.1080\/13816810.2017.1309552"},{"key":"16","doi-asserted-by":"publisher","DOI":"10.1007\/s00404-017-4322-z"}],"container-title":["Journal of Ophthalmology"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/downloads.hindawi.com\/journals\/joph\/2020\/7510903.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/downloads.hindawi.com\/journals\/joph\/2020\/7510903.xml","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/downloads.hindawi.com\/journals\/joph\/2020\/7510903.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2020,5,6]],"date-time":"2020-05-06T19:35:01Z","timestamp":1588793701000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.hindawi.com\/journals\/joph\/2020\/7510903\/"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2020,5,6]]},"references-count":16,"alternative-id":["7510903","7510903"],"URL":"https:\/\/doi.org\/10.1155\/2020\/7510903","relation":{},"ISSN":["2090-004X","2090-0058"],"issn-type":[{"value":"2090-004X","type":"print"},{"value":"2090-0058","type":"electronic"}],"subject":[],"published":{"date-parts":[[2020,5,6]]}}}