{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,21]],"date-time":"2026-02-21T03:30:40Z","timestamp":1771644640360,"version":"3.50.1"},"reference-count":30,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2020,10,26]],"date-time":"2020-10-26T00:00:00Z","timestamp":1603670400000},"content-version":"vor","delay-in-days":299,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["BioMed Research International"],"published-print":{"date-parts":[[2020,1]]},"abstract":"<jats:p><jats:italic>Objective<\/jats:italic>. To estimate the prevalence rate of ocular symptoms and the positive rate of conjunctival swab samples of patients diagnosed with 2019 Novel Coronavirus Disease (COVID\u201019). <jats:italic>Methods<\/jats:italic>. We performed a systematic review and meta\u2010analysis. A comprehensive literature search was done based on PubMed, Embase, MedRxiv, and the Cochrane Library. The primary outcomes are the prevalence rate of conjunctivitis\/conjunctival congestion and the positive rate of conjunctival swab samples. Rates were expressed as proportions with 95% confidence intervals (CIs). <jats:italic>Results<\/jats:italic>. A total of 12 studies with 1930 participants were included for meta\u2010analysis. The pooled prevalence rate of conjunctivitis\/conjunctival congestion was 8% (95% CI: 5%\u201012%). 1% (95% CI: 1%\u20104%) of COVID\u201019 patients were diagnosed with conjunctivitis\/conjunctival congestion as the initial symptom. The pooled positive rate of conjunctival swab samples was 3% (95% CI: 2%\u20105%). We also assessed other ocular symptoms reported in the 12 studies, including foreign body sensation, increased secretion, and eye itching. The pooled prevalence rates were 6% (95% CI: 3%\u201010%), 10% (95% CI: 8%\u201012%), and 9% (95% CI: 7%\u201010%), respectively. <jats:italic>Conclusions<\/jats:italic>. The evidence on the positive rate of conjunctival swab samples and the prevalence rates of ocular symptoms indicated that COVID\u201019 ocular transmission was possible but less likely.<\/jats:p>","DOI":"10.1155\/2020\/7605453","type":"journal-article","created":{"date-parts":[[2020,10,27]],"date-time":"2020-10-27T02:35:07Z","timestamp":1603766107000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":20,"title":["Current Evidence of 2019 Novel Coronavirus Disease (COVID\u201019) Ocular Transmission: A Systematic Review and 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