{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,23]],"date-time":"2026-10-23T23:50:09Z","timestamp":1792799409201,"version":"4.5.0"},"reference-count":177,"publisher":"Wiley","license":[{"start":{"date-parts":[[2020,2,5]],"date-time":"2020-02-05T00:00:00Z","timestamp":1580860800000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100005187","name":"National and Kapodistrian University of Athens","doi-asserted-by":"publisher","award":["70\/3\/1135"],"award-info":[{"award-number":["70\/3\/1135"]}],"id":[{"id":"10.13039\/501100005187","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100005187","name":"National and Kapodistrian University of Athens","doi-asserted-by":"publisher","award":["70\/3\/8916"],"award-info":[{"award-number":["70\/3\/8916"]}],"id":[{"id":"10.13039\/501100005187","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100005187","name":"National and Kapodistrian University of Athens","doi-asserted-by":"publisher","award":["70\/3\/12128"],"award-info":[{"award-number":["70\/3\/12128"]}],"id":[{"id":"10.13039\/501100005187","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100005187","name":"National and Kapodistrian University of Athens","doi-asserted-by":"publisher","award":["70\/3\/1135"],"award-info":[{"award-number":["70\/3\/1135"]}],"id":[{"id":"10.13039\/501100005187","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100005187","name":"National and Kapodistrian University of Athens","doi-asserted-by":"publisher","award":["70\/3\/8916"],"award-info":[{"award-number":["70\/3\/8916"]}],"id":[{"id":"10.13039\/501100005187","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100005187","name":"National and Kapodistrian University of Athens","doi-asserted-by":"publisher","award":["70\/3\/12128"],"award-info":[{"award-number":["70\/3\/12128"]}],"id":[{"id":"10.13039\/501100005187","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100005187","name":"National and Kapodistrian University of Athens","doi-asserted-by":"publisher","award":["70\/3\/1135"],"award-info":[{"award-number":["70\/3\/1135"]}],"id":[{"id":"10.13039\/501100005187","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100005187","name":"National and Kapodistrian University of Athens","doi-asserted-by":"publisher","award":["70\/3\/8916"],"award-info":[{"award-number":["70\/3\/8916"]}],"id":[{"id":"10.13039\/501100005187","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100005187","name":"National and Kapodistrian University of Athens","doi-asserted-by":"publisher","award":["70\/3\/12128"],"award-info":[{"award-number":["70\/3\/12128"]}],"id":[{"id":"10.13039\/501100005187","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Oxidative Medicine and Cellular Longevity"],"published-print":{"date-parts":[[2020,2,5]]},"abstract":"<jats:p>The human thymus is a primary lymphoepithelial organ which supports the production of self-tolerant T cells with competent and regulatory functions. Paradoxically, despite the crucial role that it exerts in T cell-mediated immunity and prevention of systemic autoimmunity, the thymus is the first organ of the body that exhibits age-associated degeneration\/regression, termed \u201cthymic involution.\u201d A hallmark of this early phenomenon is a progressive decline of thymic mass as well as a decreased output of na\u00efve T cells, thus resulting in impaired immune response. Importantly, thymic involution has been recently linked with cellular senescence which is a stress response induced by various stimuli. Accumulation of senescent cells in tissues has been implicated in aging and a plethora of age-related diseases. In addition, several lines of evidence indicate that oxidative stress, a well-established trigger of senescence, is also involved in thymic involution, thus highlighting a possible interplay between oxidative stress, senescence, and thymic involution.<\/jats:p>","DOI":"10.1155\/2020\/7986071","type":"journal-article","created":{"date-parts":[[2020,2,5]],"date-time":"2020-02-05T23:30:45Z","timestamp":1580945445000},"page":"1-14","source":"Crossref","is-referenced-by-count":69,"title":["Implications of Oxidative Stress and Cellular Senescence in Age-Related Thymus Involution"],"prefix":"10.1155","volume":"2020","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-6730-359X","authenticated-orcid":true,"given":"Alexandra","family":"Barbouti","sequence":"first","affiliation":[{"name":"Department of Anatomy-Histology-Embryology, Medical School, University of Ioannina, Ioannina, Greece"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6739-0619","authenticated-orcid":true,"given":"Panagiotis V. S.","family":"Vasileiou","sequence":"additional","affiliation":[{"name":"Molecular Carcinogenesis Group, Department of Histology and Embryology, Medical School, National and Kapodistrian University of Athens, Athens, Greece"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Konstantinos","family":"Evangelou","sequence":"additional","affiliation":[{"name":"Molecular Carcinogenesis Group, Department of Histology and Embryology, Medical School, National and Kapodistrian University of Athens, Athens, Greece"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Konstantinos G.","family":"Vlasis","sequence":"additional","affiliation":[{"name":"Department of Anatomy, Medical School, National and Kapodistrian University of Athens, Athens, Greece"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3932-6652","authenticated-orcid":true,"given":"Alexandra","family":"Papoudou-Bai","sequence":"additional","affiliation":[{"name":"Department of Pathology, Medical School, University of Ioannina, Ioannina, Greece"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Vassilis G.","family":"Gorgoulis","sequence":"additional","affiliation":[{"name":"Molecular Carcinogenesis Group, Department of Histology and Embryology, Medical School, National and Kapodistrian University of Athens, Athens, Greece"},{"name":"Faculty Institute for Cancer Sciences, Manchester Academic Health Sciences Centre, University of Manchester, Manchester, UK"},{"name":"Biomedical Research Foundation, Academy of Athens, Athens, Greece"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Panagiotis","family":"Kanavaros","sequence":"additional","affiliation":[{"name":"Department of Anatomy-Histology-Embryology, Medical School, University of Ioannina, Ioannina, Greece"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","reference":[{"key":"1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ceb.2010.08.003"},{"key":"2","doi-asserted-by":"publisher","DOI":"10.1016\/j.proghi.2008.03.001"},{"key":"3","doi-asserted-by":"publisher","DOI":"10.1016\/j.aanat.2012.07.012"},{"key":"4","doi-asserted-by":"publisher","DOI":"10.1038\/32588"},{"key":"5","doi-asserted-by":"publisher","DOI":"10.14670\/HH-16.1005"},{"key":"6","doi-asserted-by":"publisher","DOI":"10.1016\/S0092-8674(01)00449-4"},{"key":"7","doi-asserted-by":"publisher","DOI":"10.1038\/35095500"},{"key":"8","doi-asserted-by":"publisher","DOI":"10.1038\/icb.2014.81"},{"key":"9","doi-asserted-by":"publisher","DOI":"10.1016\/j.it.2011.03.002"},{"issue":"6","key":"10","first-page":"985","volume":"26","year":"2012","journal-title":"In Vivo"},{"key":"11","doi-asserted-by":"publisher","DOI":"10.1006\/smim.1998.0148"},{"key":"12","doi-asserted-by":"publisher","DOI":"10.1016\/j.smim.2012.04.005"},{"key":"13","doi-asserted-by":"publisher","DOI":"10.1089\/ars.2010.3228"},{"key":"14","doi-asserted-by":"publisher","DOI":"10.1016\/j.it.2009.05.001"},{"key":"15","doi-asserted-by":"publisher","DOI":"10.1002\/jemt.10409"},{"key":"16","doi-asserted-by":"publisher","DOI":"10.1152\/japplphysiol.90454.2008"},{"key":"17","doi-asserted-by":"publisher","DOI":"10.1038\/sj.ejcn.1601198"},{"issue":"3","key":"18","first-page":"280","volume":"3","year":"2012","journal-title":"Aging and Disease"},{"key":"19","doi-asserted-by":"publisher","DOI":"10.1016\/j.smim.2005.05.006"},{"key":"20","doi-asserted-by":"publisher","DOI":"10.1007\/s11357-013-9564-5"},{"key":"21","doi-asserted-by":"publisher","DOI":"10.1111\/j.0105-2896.2005.00275.x"},{"key":"22","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-3083.1985.tb01916.x"},{"key":"23","doi-asserted-by":"publisher","DOI":"10.1016\/j.exger.2017.12.022"},{"key":"24","doi-asserted-by":"publisher","DOI":"10.1016\/0167-5699(96)80543-3"},{"key":"25","doi-asserted-by":"publisher","DOI":"10.1016\/j.it.2009.04.003"},{"key":"26","doi-asserted-by":"publisher","DOI":"10.1385\/IR:22:2-3:253"},{"issue":"5","key":"27","first-page":"437","volume":"2","year":"2011","journal-title":"Aging and Disease"},{"key":"28","doi-asserted-by":"publisher","DOI":"10.1186\/1742-4933-4-9"},{"key":"29","doi-asserted-by":"publisher","DOI":"10.4049\/jimmunol.0904193"},{"key":"30","doi-asserted-by":"publisher","DOI":"10.2217\/ahe.11.56"},{"key":"31","doi-asserted-by":"publisher","DOI":"10.1111\/j.1749-6632.2009.05370.x"},{"key":"32","doi-asserted-by":"publisher","DOI":"10.1016\/j.autrev.2005.09.008"},{"key":"33","doi-asserted-by":"publisher","DOI":"10.3389\/fimmu.2013.00316"},{"key":"34","doi-asserted-by":"publisher","DOI":"10.1111\/j.1474-9726.2011.00773.x"},{"key":"35","doi-asserted-by":"publisher","DOI":"10.1111\/sji.12618"},{"key":"36","doi-asserted-by":"publisher","DOI":"10.1210\/endo.139.10.6263"},{"key":"37","doi-asserted-by":"publisher","DOI":"10.1016\/j.coph.2010.04.015"},{"key":"38","doi-asserted-by":"publisher","DOI":"10.1038\/nrendo.2015.168"},{"key":"39","doi-asserted-by":"publisher","DOI":"10.1016\/j.celrep.2015.07.008"},{"key":"40","doi-asserted-by":"publisher","DOI":"10.1007\/s00018-014-1691-3"},{"key":"41","doi-asserted-by":"publisher","DOI":"10.18632\/aging.100527"},{"key":"42","doi-asserted-by":"publisher","DOI":"10.1016\/j.cell.2019.10.005"},{"key":"43","doi-asserted-by":"publisher","DOI":"10.1016\/j.ceb.2010.07.013"},{"key":"44","doi-asserted-by":"publisher","DOI":"10.18632\/aging.100989"},{"key":"45","doi-asserted-by":"publisher","DOI":"10.1038\/nrm3823"},{"key":"46","doi-asserted-by":"publisher","DOI":"10.1083\/jcb.201009094"},{"key":"47","doi-asserted-by":"publisher","DOI":"10.1101\/gad.235184.113"},{"key":"48","doi-asserted-by":"publisher","DOI":"10.1038\/nature05268"},{"key":"49","doi-asserted-by":"publisher","DOI":"10.1126\/science.1140735"},{"key":"50","doi-asserted-by":"publisher","DOI":"10.1158\/0008-5472.CAN-07-2837"},{"key":"51","doi-asserted-by":"publisher","DOI":"10.2353\/ajpath.2009.081160"},{"key":"52","doi-asserted-by":"publisher","DOI":"10.1038\/nrm2233"},{"key":"53","doi-asserted-by":"publisher","DOI":"10.1146\/annurev-pathol-121808-102144"},{"key":"54","doi-asserted-by":"publisher","DOI":"10.1038\/labinvest.3700241"},{"key":"55","doi-asserted-by":"publisher","DOI":"10.1093\/emboj\/cdg157"},{"key":"56","doi-asserted-by":"publisher","DOI":"10.1111\/dom.12719"},{"key":"57","doi-asserted-by":"publisher","DOI":"10.1126\/science.1122446"},{"issue":"6","key":"58","first-page":"1933","volume":"150","year":"1997","journal-title":"The American Journal of Pathology"},{"key":"59","doi-asserted-by":"publisher","DOI":"10.1046\/j.1474-9728.2002.00008.x"},{"key":"60","doi-asserted-by":"publisher","DOI":"10.1038\/nrneph.2016.183"},{"key":"61","doi-asserted-by":"publisher","DOI":"10.1096\/fj.00-0051com"},{"key":"62","doi-asserted-by":"publisher","DOI":"10.1111\/j.1474-9726.2007.00365.x"},{"key":"63","doi-asserted-by":"publisher","DOI":"10.1016\/j.mad.2018.02.005"},{"key":"64","doi-asserted-by":"publisher","DOI":"10.1007\/s11357-017-0002-y"},{"key":"65","doi-asserted-by":"publisher","DOI":"10.1016\/j.bbrc.2018.05.045"},{"key":"66","doi-asserted-by":"publisher","DOI":"10.1085\/jgp.49.1.29"},{"key":"67","doi-asserted-by":"publisher","DOI":"10.1155\/2016\/1245049"},{"key":"68","doi-asserted-by":"publisher","DOI":"10.1042\/BJ20081386"},{"key":"69","doi-asserted-by":"publisher","DOI":"10.1113\/jphysiol.2003.049478"},{"key":"70","doi-asserted-by":"publisher","DOI":"10.1016\/j.cotox.2018.01.002"},{"key":"71","doi-asserted-by":"publisher","DOI":"10.1016\/j.redox.2015.01.002"},{"key":"72","doi-asserted-by":"publisher","DOI":"10.4314\/ambr.v2i4.6"},{"key":"73","doi-asserted-by":"publisher","DOI":"10.1152\/physrev.00010.2014"},{"key":"74","doi-asserted-by":"publisher","DOI":"10.3389\/fphar.2014.00045"},{"key":"75","doi-asserted-by":"publisher","DOI":"10.1080\/10408360701713104"},{"key":"76","doi-asserted-by":"publisher","DOI":"10.1016\/j.bbamcr.2019.118535"},{"key":"77","doi-asserted-by":"publisher","DOI":"10.1007\/s00204-015-1579-5"},{"key":"78","doi-asserted-by":"publisher","DOI":"10.1016\/B978-0-12-642760-8.50005-3"},{"key":"79","first-page":"45","volume-title":"Oxidative stress","year":"2007"},{"key":"80","doi-asserted-by":"publisher","DOI":"10.1016\/j.freeradbiomed.2012.11.001"},{"key":"81","doi-asserted-by":"publisher","DOI":"10.1155\/2016\/3565127"},{"key":"82","doi-asserted-by":"publisher","DOI":"10.1038\/35041687"},{"key":"83","doi-asserted-by":"publisher","DOI":"10.1007\/BF03401502"},{"key":"84","doi-asserted-by":"publisher","DOI":"10.1016\/j.freeradbiomed.2018.06.016"},{"key":"85","doi-asserted-by":"publisher","DOI":"10.1186\/2046-2395-3-6"},{"key":"86","doi-asserted-by":"publisher","DOI":"10.1152\/ajpregu.00327.2006"},{"key":"87","doi-asserted-by":"publisher","DOI":"10.1016\/j.freeradbiomed.2014.03.038"},{"key":"88","doi-asserted-by":"publisher","DOI":"10.1016\/j.freeradbiomed.2013.02.011"},{"key":"89","doi-asserted-by":"publisher","DOI":"10.1016\/B978-0-12-394625-6.00001-5"},{"key":"90","doi-asserted-by":"publisher","DOI":"10.1007\/s10522-015-9585-9"},{"key":"91","doi-asserted-by":"publisher","DOI":"10.1016\/j.freeradbiomed.2007.03.034"},{"key":"92","doi-asserted-by":"publisher","DOI":"10.1126\/science.273.5271.59"},{"key":"93","doi-asserted-by":"publisher","DOI":"10.1016\/j.freeradbiomed.2015.05.005"},{"key":"94","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.94.2.514"},{"key":"95","doi-asserted-by":"publisher","DOI":"10.1038\/cdd.2016.123"},{"key":"96","doi-asserted-by":"publisher","DOI":"10.1101\/cshperspect.a012641"},{"key":"97","doi-asserted-by":"publisher","DOI":"10.1038\/nrm3439"},{"key":"98","doi-asserted-by":"publisher","DOI":"10.3390\/ijms18081821"},{"key":"99","doi-asserted-by":"publisher","DOI":"10.1016\/j.cell.2015.02.020"},{"key":"100","doi-asserted-by":"publisher","DOI":"10.1113\/JP270543"},{"key":"101","doi-asserted-by":"publisher","DOI":"10.1016\/j.bbamcr.2010.10.007"},{"key":"102","doi-asserted-by":"publisher","DOI":"10.1016\/j.bbamcr.2011.01.029"},{"key":"103","doi-asserted-by":"publisher","DOI":"10.1016\/j.cellsig.2012.01.008"},{"key":"104","doi-asserted-by":"publisher","DOI":"10.3390\/cells8070686"},{"key":"105","doi-asserted-by":"publisher","DOI":"10.1186\/1472-6882-13-193"},{"key":"106","doi-asserted-by":"publisher","DOI":"10.1007\/s12011-015-0598-7"},{"key":"107","doi-asserted-by":"publisher","DOI":"10.1016\/j.fitote.2012.01.006"},{"key":"108","doi-asserted-by":"publisher","DOI":"10.1007\/s10534-014-9804-x"},{"key":"109","doi-asserted-by":"publisher","DOI":"10.3382\/ps\/pev055"},{"key":"110","doi-asserted-by":"publisher","DOI":"10.1007\/s12011-012-9439-0"},{"key":"111","doi-asserted-by":"publisher","DOI":"10.1007\/s10534-013-9612-8"},{"key":"112","doi-asserted-by":"publisher","DOI":"10.1017\/S0007114514003857"},{"key":"113","doi-asserted-by":"publisher","DOI":"10.1016\/s0047-6374(01)00232-9"},{"key":"114","doi-asserted-by":"publisher","DOI":"10.1155\/2014\/320513"},{"key":"115","doi-asserted-by":"publisher","DOI":"10.18632\/aging.100043"},{"key":"116","doi-asserted-by":"publisher","DOI":"10.1016\/bs.pmbts.2016.12.015"},{"key":"117","doi-asserted-by":"publisher","DOI":"10.1126\/science.1106653"},{"key":"118","doi-asserted-by":"publisher","DOI":"10.1016\/j.bbamcr.2006.09.006"},{"key":"119","doi-asserted-by":"publisher","DOI":"10.1007\/bf00916279"},{"key":"120","doi-asserted-by":"publisher","DOI":"10.1146\/annurev.bi.61.070192.001105"},{"issue":"2","key":"121","doi-asserted-by":"crossref","first-page":"1020","DOI":"10.1016\/S0021-9258(17)42214-9","volume":"269","year":"1994","journal-title":"The Journal of Biological Chemistry"},{"key":"122","doi-asserted-by":"publisher","DOI":"10.1074\/jbc.M404800200"},{"key":"123","doi-asserted-by":"publisher","DOI":"10.1111\/imr.12412"},{"key":"124","volume":"202, article 65.15","year":"2019","journal-title":"The Journal of Immunology"},{"key":"125","doi-asserted-by":"publisher","DOI":"10.1074\/jbc.R113.544635"},{"key":"126","doi-asserted-by":"publisher","DOI":"10.1016\/j.freeradbiomed.2007.06.020"},{"key":"127","doi-asserted-by":"publisher","DOI":"10.1016\/j.redox.2018.01.014"},{"key":"128","doi-asserted-by":"publisher","DOI":"10.1016\/j.redox.2016.10.006"},{"key":"129","doi-asserted-by":"publisher","DOI":"10.1016\/j.freeradbiomed.2016.07.002"},{"key":"130","doi-asserted-by":"publisher","DOI":"10.1016\/j.tibs.2015.11.012"},{"key":"131","doi-asserted-by":"publisher","DOI":"10.2174\/1567205012666150921103304"},{"key":"132","doi-asserted-by":"publisher","DOI":"10.3389\/fphar.2015.00026"},{"key":"133","doi-asserted-by":"publisher","DOI":"10.3390\/ijms17010130"},{"key":"134","doi-asserted-by":"publisher","DOI":"10.1016\/S1568-1637(02)00048-X"},{"key":"135","doi-asserted-by":"publisher","DOI":"10.1186\/s12868-017-0369-9"},{"key":"136","doi-asserted-by":"publisher","DOI":"10.1089\/ars.2014.5837"},{"key":"137","doi-asserted-by":"publisher","DOI":"10.1007\/978-1-62703-239-1_3"},{"key":"138","doi-asserted-by":"publisher","DOI":"10.1038\/msb.2010.5"},{"key":"139","doi-asserted-by":"publisher","DOI":"10.1046\/j.1365-2443.2003.00620.x"},{"key":"140","doi-asserted-by":"publisher","DOI":"10.1152\/physrev.2001.81.2.807"},{"key":"141","doi-asserted-by":"publisher","DOI":"10.1038\/ncb1491"},{"key":"142","doi-asserted-by":"publisher","DOI":"10.2174\/156652412800792633"},{"key":"143","doi-asserted-by":"publisher","DOI":"10.1128\/MCB.02240-05"},{"key":"144","doi-asserted-by":"publisher","DOI":"10.1016\/j.freeradbiomed.2010.01.030"},{"key":"145","doi-asserted-by":"publisher","DOI":"10.1096\/fj.99-0843com"},{"key":"146","doi-asserted-by":"publisher","DOI":"10.1111\/acel.12545"},{"key":"147","doi-asserted-by":"publisher","DOI":"10.1007\/978-1-4939-6670-7_10"},{"key":"148","doi-asserted-by":"publisher","DOI":"10.14670\/HH-15.445"},{"key":"149","doi-asserted-by":"publisher","DOI":"10.1038\/s41467-019-11879-2"},{"key":"150","doi-asserted-by":"publisher","DOI":"10.1089\/ars.2006.8.197"},{"key":"151","doi-asserted-by":"publisher","DOI":"10.1084\/jem.20122149"},{"key":"152","doi-asserted-by":"publisher","DOI":"10.1556\/ABiol.57.2006.3.5"},{"key":"153","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-0463.2009.02437.x"},{"key":"154","doi-asserted-by":"publisher","DOI":"10.4161\/auto.4144"},{"key":"155","doi-asserted-by":"publisher","DOI":"10.1007\/s11357-011-9221-9"},{"key":"156","doi-asserted-by":"publisher","DOI":"10.1016\/j.arr.2012.05.001"},{"key":"157","doi-asserted-by":"publisher","DOI":"10.1016\/j.redox.2013.01.006"},{"key":"158","doi-asserted-by":"publisher","DOI":"10.2174\/13816128113196660709"},{"key":"159","doi-asserted-by":"publisher","DOI":"10.1016\/j.cell.2007.12.018"},{"key":"160","doi-asserted-by":"publisher","DOI":"10.1016\/j.cell.2011.07.030"},{"key":"161","doi-asserted-by":"publisher","DOI":"10.1080\/15548627.2016.1247143"},{"key":"162","doi-asserted-by":"publisher","DOI":"10.15252\/embj.201592862"},{"key":"163","doi-asserted-by":"publisher","DOI":"10.1016\/j.bbabio.2015.05.017"},{"key":"164","doi-asserted-by":"publisher","DOI":"10.1016\/j.cell.2013.05.039"},{"key":"165","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0032117"},{"key":"166","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pbio.0050110"},{"key":"167","doi-asserted-by":"publisher","DOI":"10.1046\/j.1432-1033.2002.02869.x"},{"key":"168","doi-asserted-by":"publisher","DOI":"10.1089\/ars.2009.2598"},{"key":"169","doi-asserted-by":"publisher","DOI":"10.1111\/acel.12446"},{"key":"170","doi-asserted-by":"publisher","DOI":"10.18632\/oncotarget.2874"},{"key":"171","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0023367"},{"key":"172","doi-asserted-by":"publisher","DOI":"10.1016\/j.mad.2016.03.010"},{"key":"173","doi-asserted-by":"publisher","DOI":"10.1016\/j.pharmthera.2018.08.006"},{"key":"174","doi-asserted-by":"publisher","DOI":"10.1080\/15384101.2016.1232088"},{"issue":"1","key":"175","first-page":"7","volume":"18","year":"1991","journal-title":"Thymus"},{"key":"176","doi-asserted-by":"publisher","DOI":"10.1007\/s10238-015-0344-7"},{"key":"177","doi-asserted-by":"publisher","DOI":"10.1046\/j.1365-2559.1997.5730805.x"}],"container-title":["Oxidative Medicine and Cellular Longevity"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/downloads.hindawi.com\/journals\/omcl\/2020\/7986071.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/downloads.hindawi.com\/journals\/omcl\/2020\/7986071.xml","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/downloads.hindawi.com\/journals\/omcl\/2020\/7986071.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2021,2,26]],"date-time":"2021-02-26T02:44:27Z","timestamp":1614307467000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.hindawi.com\/journals\/omcl\/2020\/7986071\/"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2020,2,5]]},"references-count":177,"alternative-id":["7986071","7986071"],"URL":"https:\/\/doi.org\/10.1155\/2020\/7986071","relation":{},"ISSN":["1942-0900","1942-0994"],"issn-type":[{"value":"1942-0900","type":"print"},{"value":"1942-0994","type":"electronic"}],"subject":[],"published":{"date-parts":[[2020,2,5]]}}}