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It is challenging to analyze the gene expression network through relevant knowledge and algorithms of a complex network. In this paper, the existing characteristics of genes are analyzed from various indexes of the gene expression network to analyze key genes and TOP genes. Firstly, gene chip data are screened, gene data with obvious characteristics are selected, and relevant clustering characteristics are analyzed. Then, the complex gene network structure is established, and gene networks with different threshold shapes and different sizes are selected. Finally, the relevant indexes and PR values after the PageRank algorithm are analyzed for complex networks under different thresholds, thus establishing the TOP gene and PR sequence.<\/jats:p>","DOI":"10.1155\/2020\/8816633","type":"journal-article","created":{"date-parts":[[2020,12,10]],"date-time":"2020-12-10T20:22:30Z","timestamp":1607631750000},"page":"1-12","source":"Crossref","is-referenced-by-count":6,"title":["Analysis and Research of Key Genes in Gene Expression Network Based on Complex Network"],"prefix":"10.1155","volume":"2020","author":[{"given":"Guobin","family":"Chen","sequence":"first","affiliation":[{"name":"Chongqing Key Laboratory of Spatial Data Mining and Big Data Integration for Ecology and Environment, Rongzhi College of Chongqing Technology and Business University, Chongqing 401320, China"}]},{"given":"Jun","family":"Qi","sequence":"additional","affiliation":[{"name":"Radiation & Cancer Biology Laboratory, Chongqing University Cancer Hospital & Chongqing Cancer Institute & Chongqing Cancer Hospital, Chongqing 400030, China"},{"name":"Chongqing Key Laboratory of Translational Research for Cancer Metastasis and Individualized Treatment, Chongqing University Cancer Hospital, Chongqing 400030, China"}]},{"given":"Chao","family":"Tang","sequence":"additional","affiliation":[{"name":"Radiation & Cancer Biology Laboratory, Chongqing University Cancer Hospital & Chongqing Cancer Institute & Chongqing Cancer Hospital, Chongqing 400030, China"},{"name":"Chongqing Key Laboratory of Translational Research for Cancer Metastasis and Individualized Treatment, Chongqing University Cancer Hospital, Chongqing 400030, China"}]},{"given":"Ying","family":"Wang","sequence":"additional","affiliation":[{"name":"Radiation & Cancer Biology Laboratory, Chongqing University Cancer Hospital & Chongqing Cancer Institute & Chongqing Cancer Hospital, Chongqing 400030, China"},{"name":"Chongqing Key Laboratory of Translational Research for Cancer Metastasis and Individualized Treatment, Chongqing University Cancer Hospital, Chongqing 400030, China"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8367-3347","authenticated-orcid":true,"given":"Yongzhong","family":"Wu","sequence":"additional","affiliation":[{"name":"Radiation & Cancer Biology Laboratory, Chongqing University Cancer Hospital & Chongqing Cancer Institute & Chongqing Cancer Hospital, Chongqing 400030, China"},{"name":"Chongqing Key Laboratory of Translational Research for Cancer Metastasis and Individualized Treatment, Chongqing University Cancer Hospital, Chongqing 400030, China"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0038-5049","authenticated-orcid":true,"given":"Xiaolong","family":"Shi","sequence":"additional","affiliation":[{"name":"Radiation & Cancer Biology Laboratory, Chongqing University Cancer Hospital & Chongqing Cancer Institute & Chongqing Cancer Hospital, Chongqing 400030, China"},{"name":"Chongqing Key Laboratory of Translational Research for Cancer Metastasis and Individualized Treatment, Chongqing University Cancer Hospital, Chongqing 400030, China"}]}],"member":"311","reference":[{"key":"1","doi-asserted-by":"publisher","DOI":"10.1104\/pp.111.173047"},{"key":"2","doi-asserted-by":"publisher","DOI":"10.3389\/fgene.2018.00121"},{"key":"3","doi-asserted-by":"publisher","DOI":"10.1016\/j.compbiolchem.2020.107323"},{"key":"4","doi-asserted-by":"publisher","DOI":"10.1016\/j.compbiolchem.2019.04.010"},{"key":"5","doi-asserted-by":"publisher","DOI":"10.1038\/s41596-020-0336-2"},{"key":"6","doi-asserted-by":"publisher","DOI":"10.1021\/acsptsci.0c00024"},{"key":"7","doi-asserted-by":"publisher","DOI":"10.1016\/0022-5193(69)90015-0"},{"key":"8","doi-asserted-by":"publisher","DOI":"10.1021\/jm2013198"},{"key":"9","doi-asserted-by":"publisher","DOI":"10.1021\/jm2012886"},{"key":"10","first-page":"41","article-title":"Linear modeling of m RNA expression levels during CNS development and injury","volume":"4","author":"P. 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