{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,5,14]],"date-time":"2025-05-14T02:39:29Z","timestamp":1747190369063,"version":"3.40.5"},"reference-count":10,"publisher":"Wiley","license":[{"start":{"date-parts":[[2020,11,1]],"date-time":"2020-11-01T00:00:00Z","timestamp":1604188800000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Case Reports in Ophthalmological Medicine"],"published-print":{"date-parts":[[2020,11,1]]},"abstract":"<jats:p>Purpose. To report a case of isolated superior oblique muscle swelling causing acute vertical strabismus in Graves\u2019 disease. Case. A 26-year-old woman with a 1-month history of misalignment of the right eye and diplopia was referred to us. Her visual acuity and intraocular pressures were normal in both eyes, but eye movement tests showed clear misalignment of her right eye. Antibody tests for myasthenia gravis were negative. However, blood tests revealed abnormal levels of thyroid-related factors, such as decreased thyroid-stimulating hormone, elevated free T3 and T4, and elevated anti-thyroid-stimulating hormone receptor antibody. We performed magnetic resonance imaging (MRI), which showed slight enlargement of the left superior oblique muscle. The patient was eventually diagnosed with Graves\u2019 disease with superior oblique muscle involvement and underwent a thyroidectomy. Three months postoperatively, her diplopia and abnormal eye movements had substantially resolved. Conclusion. Isolated superior oblique muscle involvement may be a presenting symptom of Graves\u2019 disease. It should be taken into consideration that, in the early stages of thyroid-associated ophthalmopathy (TAO) in adults, only the superior oblique muscle may be enlarged.<\/jats:p>","DOI":"10.1155\/2020\/8829655","type":"journal-article","created":{"date-parts":[[2020,11,2]],"date-time":"2020-11-02T22:50:08Z","timestamp":1604357408000},"page":"1-4","source":"Crossref","is-referenced-by-count":1,"title":["Isolated Superior Oblique Muscle Swelling Causing Acute Vertical Strabismus in Graves\u2019 Disease"],"prefix":"10.1155","volume":"2020","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-1828-4446","authenticated-orcid":true,"given":"Keiichi","family":"Aomatsu","sequence":"first","affiliation":[{"name":"Department of Ophthalmology, Nara Hospital, Kindai University Faculty of Medicine, Nara, Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Shunji","family":"Kusaka","sequence":"additional","affiliation":[{"name":"Department of Ophthalmology, Kindai University Faculty of Medicine, Osaka, Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","reference":[{"issue":"2","key":"1","first-page":"94","article-title":"Thyroid ophthalmopathy presenting as superior oblique paresis","volume":"12","author":"M. L. Moster","year":"1992","journal-title":"Journal of Clinical Neuro-Ophthalmology"},{"key":"2","doi-asserted-by":"publisher","DOI":"10.1097\/WNO.0b013e31818f133e"},{"key":"3","doi-asserted-by":"publisher","DOI":"10.1016\/S1607-551X(09)70090-7"},{"key":"4","doi-asserted-by":"publisher","DOI":"10.1016\/j.jaapos.2004.12.005"},{"key":"5","doi-asserted-by":"publisher","DOI":"10.1016\/S0161-6420(89)32933-2"},{"key":"6","doi-asserted-by":"publisher","DOI":"10.1159\/000131894"},{"key":"7","doi-asserted-by":"publisher","DOI":"10.1007\/s004170100352"},{"key":"8","doi-asserted-by":"publisher","DOI":"10.1016\/j.jaapos.2011.04.003"},{"key":"9","first-page":"11","article-title":"Isolated hypertrophy of the superior oblique muscle in Basedow disease","volume":"295","author":"M. C. Charif","year":"2005","journal-title":"Bulletin de la Societe belge d'ophtalmologie"},{"key":"10","doi-asserted-by":"publisher","DOI":"10.1111\/j.1755-3768.1993.tb05000.x"}],"container-title":["Case Reports in Ophthalmological Medicine"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/downloads.hindawi.com\/journals\/criopm\/2020\/8829655.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/downloads.hindawi.com\/journals\/criopm\/2020\/8829655.xml","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/downloads.hindawi.com\/journals\/criopm\/2020\/8829655.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2020,11,2]],"date-time":"2020-11-02T22:50:13Z","timestamp":1604357413000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.hindawi.com\/journals\/criopm\/2020\/8829655\/"}},"subtitle":[],"editor":[{"given":"Claudio","family":"Campa","sequence":"additional","affiliation":[],"role":[{"role":"editor","vocabulary":"crossref"}]}],"short-title":[],"issued":{"date-parts":[[2020,11,1]]},"references-count":10,"alternative-id":["8829655","8829655"],"URL":"https:\/\/doi.org\/10.1155\/2020\/8829655","relation":{},"ISSN":["2090-6730","2090-6722"],"issn-type":[{"type":"electronic","value":"2090-6730"},{"type":"print","value":"2090-6722"}],"subject":[],"published":{"date-parts":[[2020,11,1]]}}}