{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,12,11]],"date-time":"2025-12-11T20:55:12Z","timestamp":1765486512434,"version":"3.37.3"},"reference-count":16,"publisher":"Wiley","license":[{"start":{"date-parts":[[2020,12,5]],"date-time":"2020-12-05T00:00:00Z","timestamp":1607126400000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100004775","name":"Natural Science Foundation of Gansu Province","doi-asserted-by":"publisher","award":["1606RJZA152","2019-ZD-56","2017\u201312"],"award-info":[{"award-number":["1606RJZA152","2019-ZD-56","2017\u201312"]}],"id":[{"id":"10.13039\/501100004775","id-type":"DOI","asserted-by":"publisher"}]},{"name":"Lanzhou Science and Technology Development Project","award":["1606RJZA152","2019-ZD-56","2017\u201312"],"award-info":[{"award-number":["1606RJZA152","2019-ZD-56","2017\u201312"]}]},{"name":"Cuiying Graduate Supervisor Applicant Training Program of Lanzhou University Second Hospital","award":["1606RJZA152","2019-ZD-56","2017\u201312"],"award-info":[{"award-number":["1606RJZA152","2019-ZD-56","2017\u201312"]}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Canadian Journal of Gastroenterology and Hepatology"],"published-print":{"date-parts":[[2020,12,5]]},"abstract":"<jats:p>Aim. Portal hypertension is a series of syndrome commonly seen with advanced cirrhosis, which seriously affects patient\u2019s quality of life and survival. This study was designed to access the efficacy and safety of selective esophagogastric devascularization in the modified Sugiura procedure for patients with cirrhotic hemorrhagic portal hypertension. Methods. Sixty patients with hepatitis B cirrhotic hemorrhagic portal hypertension and meeting the inclusion criteria were selected and randomly divided by using computer into the selective modified Sugiura group (sMSP group, n\u2009=\u200930) and the modified Sugiura group (MSP group, n\u2009=\u200930). The primary endpoint measurement is the postoperative rebleeding rate. Secondary endpoint measurements included free portal venous pressure, liver Child\u2013Pugh score, liver volume, portal vein width and blood flow velocity, survival rate, quality of life, and dysphagia as well as other complications one year postoperatively. This trial is registered with ChiCTR, number ChiCTR2000033468. Results. There was no statistically significant difference in rebleeding rates within one year after surgery between patients in the sMSP and MSP groups (\u03c7\u2009=\u20090.11, <jats:inline-formula>\n                     <a:math xmlns:a=\"http:\/\/www.w3.org\/1998\/Math\/MathML\" id=\"M1\">\n                        <a:mi>p<\/a:mi>\n                        <a:mo>=<\/a:mo>\n                        <a:mn>0.73<\/a:mn>\n                     <\/a:math>\n                  <\/jats:inline-formula>). In comparison with the MSP group, the Child\u2013Pugh score of liver function in the sMSP group significantly increased (\u03c7\u2009=\u20096.4, <jats:inline-formula>\n                     <c:math xmlns:c=\"http:\/\/www.w3.org\/1998\/Math\/MathML\" id=\"M2\">\n                        <c:mi>p<\/c:mi>\n                        <c:mo>=<\/c:mo>\n                        <c:mn>0.04<\/c:mn>\n                     <\/c:math>\n                  <\/jats:inline-formula>) and the incidence of dysphagia was significantly reduced (\u03c7\u2009=\u20096.23, <jats:inline-formula>\n                     <e:math xmlns:e=\"http:\/\/www.w3.org\/1998\/Math\/MathML\" id=\"M3\">\n                        <e:mi>p<\/e:mi>\n                        <e:mo>=<\/e:mo>\n                        <e:mn>0.01<\/e:mn>\n                     <\/e:math>\n                  <\/jats:inline-formula>) one year after surgery. There was a statistically significant difference in the quality of life between the two groups. However, there were no statistically significant differences in free portal venous pressure (MD\u2009=\u2009\u22123.44, 95% CI: \u22127.87 to 0.98, <jats:inline-formula>\n                     <g:math xmlns:g=\"http:\/\/www.w3.org\/1998\/Math\/MathML\" id=\"M4\">\n                        <g:mi>p<\/g:mi>\n                        <g:mo>=<\/g:mo>\n                        <g:mn>0.12<\/g:mn>\n                     <\/g:math>\n                  <\/jats:inline-formula>), postoperative liver volume (3 months: MD\u2009=\u2009-258.81, 95% CI: \u2212723.21 to 205.57, <jats:inline-formula>\n                     <i:math xmlns:i=\"http:\/\/www.w3.org\/1998\/Math\/MathML\" id=\"M5\">\n                        <i:mi>p<\/i:mi>\n                        <i:mo>=<\/i:mo>\n                        <i:mn>0.24<\/i:mn>\n                     <\/i:math>\n                  <\/jats:inline-formula>; 1 year: MD\u2009=\u2009\u2212320.12, 95% CI: \u2212438.43 to 102.78, <jats:inline-formula>\n                     <k:math xmlns:k=\"http:\/\/www.w3.org\/1998\/Math\/MathML\" id=\"M6\">\n                        <k:mi>p<\/k:mi>\n                        <k:mo>=<\/k:mo>\n                        <k:mn>0.16<\/k:mn>\n                     <\/k:math>\n                  <\/jats:inline-formula>), postoperative portal vein width (3 months: MD\u2009=\u2009\u22120.06, <jats:inline-formula>\n                     <m:math xmlns:m=\"http:\/\/www.w3.org\/1998\/Math\/MathML\" id=\"M7\">\n                        <m:mi>p<\/m:mi>\n                        <m:mo>=<\/m:mo>\n                        <m:mn>0.50<\/m:mn>\n                     <\/m:math>\n                  <\/jats:inline-formula>; 1 year: MD\u2009=\u20090.17, <jats:inline-formula>\n                     <o:math xmlns:o=\"http:\/\/www.w3.org\/1998\/Math\/MathML\" id=\"M8\">\n                        <o:mi>p<\/o:mi>\n                        <o:mo>=<\/o:mo>\n                        <o:mn>0.21<\/o:mn>\n                     <\/o:math>\n                  <\/jats:inline-formula>), portal vein flow velocity (3 months: MD\u2009=\u20091.64, <jats:inline-formula>\n                     <q:math xmlns:q=\"http:\/\/www.w3.org\/1998\/Math\/MathML\" id=\"M9\">\n                        <q:mi>p<\/q:mi>\n                        <q:mo>=<\/q:mo>\n                        <q:mn>0.21<\/q:mn>\n                     <\/q:math>\n                  <\/jats:inline-formula>; 1 year: MD\u2009=\u2009\u22121.19, <jats:inline-formula>\n                     <s:math xmlns:s=\"http:\/\/www.w3.org\/1998\/Math\/MathML\" id=\"M10\">\n                        <s:mi>p<\/s:mi>\n                        <s:mo>=<\/s:mo>\n                        <s:mn>0.57<\/s:mn>\n                     <\/s:math>\n                  <\/jats:inline-formula>), 1-year survival rate (\u03c7\u2009=\u20091.01, <jats:inline-formula>\n                     <u:math xmlns:u=\"http:\/\/www.w3.org\/1998\/Math\/MathML\" id=\"M11\">\n                        <u:mi>p<\/u:mi>\n                        <u:mo>=<\/u:mo>\n                        <u:mn>0.31<\/u:mn>\n                     <\/u:math>\n                  <\/jats:inline-formula>), and other complications between the two groups. Conclusions. Selective esophagogastric devascularization in the modified Sugiura procedure may not lower the incidence of rebleeding in the short term based on our findings. However, it may significantly improve quality of life of patients with cirrhotic hemorrhagic portal hypertension, improve liver function, and reduce postoperative dysphagia.<\/jats:p>","DOI":"10.1155\/2020\/8839098","type":"journal-article","created":{"date-parts":[[2020,12,8]],"date-time":"2020-12-08T17:30:09Z","timestamp":1607448609000},"page":"1-8","source":"Crossref","is-referenced-by-count":2,"title":["Selective Esophagogastric Devascularization in the Modified Sugiura Procedure for Patients with Cirrhotic Hemorrhagic Portal Hypertension: A Randomized Controlled Trial"],"prefix":"10.1155","volume":"2020","author":[{"given":"Yawu","family":"Zhang","sequence":"first","affiliation":[{"name":"Department of General Surgery, Lanzhou University Second Hospital, Lanzhou 730030, China"},{"name":"Hepato-Biliary-Pancreatic Institute, Lanzhou University Second Hospital, Lanzhou 730030, China"},{"name":"Gansu Provincial-Level Key Laboratory of Digestive System Tumors, Lanzhou 730030, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Lingyi","family":"Zhang","sequence":"additional","affiliation":[{"name":"Department of General Surgery, Lanzhou University Second Hospital, Lanzhou 730030, China"},{"name":"Gansu Provincial-Level Key Laboratory of Digestive System Tumors, Lanzhou 730030, China"},{"name":"Department of Hepatology, Lanzhou University Second Hospital, Lanzhou 730030, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6141-3015","authenticated-orcid":true,"given":"Mancai","family":"Wang","sequence":"additional","affiliation":[{"name":"Department of General Surgery, Lanzhou University Second Hospital, Lanzhou 730030, China"},{"name":"Hepato-Biliary-Pancreatic Institute, Lanzhou University Second Hospital, Lanzhou 730030, China"},{"name":"Gansu Provincial-Level Key Laboratory of Digestive System Tumors, Lanzhou 730030, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Xiaoling","family":"Luo","sequence":"additional","affiliation":[{"name":"Department of General Surgery, Lanzhou University Second Hospital, Lanzhou 730030, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Zheyuan","family":"Wang","sequence":"additional","affiliation":[{"name":"Department of General Surgery, Lanzhou University Second Hospital, Lanzhou 730030, China"},{"name":"Hepato-Biliary-Pancreatic Institute, Lanzhou University Second Hospital, Lanzhou 730030, China"},{"name":"Gansu Provincial-Level Key Laboratory of Digestive System Tumors, Lanzhou 730030, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Gennian","family":"Wang","sequence":"additional","affiliation":[{"name":"Department of General Surgery, Lanzhou University Second Hospital, Lanzhou 730030, China"},{"name":"Hepato-Biliary-Pancreatic Institute, Lanzhou University Second Hospital, Lanzhou 730030, 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therapy for portal hypertension in patients with cirrhosis in China: present situation and prospects","volume":"122","author":"G. 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