{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,5,14]],"date-time":"2025-05-14T02:38:42Z","timestamp":1747190322423,"version":"3.40.5"},"reference-count":16,"publisher":"Wiley","license":[{"start":{"date-parts":[[2020,11,30]],"date-time":"2020-11-30T00:00:00Z","timestamp":1606694400000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100019035","name":"Science and technology project of Hubei Province","doi-asserted-by":"crossref","award":["2020FCA014"],"award-info":[{"award-number":["2020FCA014"]}],"id":[{"id":"10.13039\/501100019035","id-type":"DOI","asserted-by":"crossref"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Gastroenterology Research and Practice"],"published-print":{"date-parts":[[2020,11,30]]},"abstract":"<jats:p>The incidence of digestive symptoms may vary depending on doctors\u2019 professional backgrounds when they inquired suspected COVID-19 patients in a fever clinic. We sought to understand the characteristics of inquiries about digestive symptoms by doctors in different specialties; therefore, inquiry records of 2 gastroenterologists and 6 nongastroenterologists were reviewed. We compared the difference in inquiry of digestive symptoms (diarrhea, vomit, distension, anorexia, and abdominal pain) between these two groups among identified COVID-19 patients. And we further compared the difference of digestive symptoms between confirmed patients and suspected cases who excluded from COVID-19. Among 495 confirmed COVID-19 cases (254 cases by gastroenterologists and 241 cases by nongastroenterologists), 22.83% patients experienced various digestive symptoms in the gastroenterologists\u2019 group, while only 4.47% reported digestive symptoms by nongastroenterologists (<jats:inline-formula>\n                     <a:math xmlns:a=\"http:\/\/www.w3.org\/1998\/Math\/MathML\" id=\"M1\">\n                        <a:mi>p<\/a:mi>\n                        <a:mo>&lt;<\/a:mo>\n                        <a:mn>0.0001<\/a:mn>\n                     <\/a:math>\n                  <\/jats:inline-formula>). Additionally, among initially suspected 611 patients who presented with similar respiratory symptoms inquired by gastroenterologists, confirmed cases presented far more frequency of digestive symptoms than excluded cases (22.8% vs. 3.64%, <jats:inline-formula>\n                     <c:math xmlns:c=\"http:\/\/www.w3.org\/1998\/Math\/MathML\" id=\"M2\">\n                        <c:mi>p<\/c:mi>\n                        <c:mo>&lt;<\/c:mo>\n                        <c:mn>0.0001<\/c:mn>\n                     <\/c:math>\n                  <\/jats:inline-formula>). Furthermore, confirmed patients reported more percentage of watery diarrhea (56% vs. 36%, <jats:inline-formula>\n                     <e:math xmlns:e=\"http:\/\/www.w3.org\/1998\/Math\/MathML\" id=\"M3\">\n                        <e:mi>p<\/e:mi>\n                        <e:mo>&lt;<\/e:mo>\n                        <e:mn>0.0001<\/e:mn>\n                     <\/e:math>\n                  <\/jats:inline-formula>) and higher frequent vomit (<jats:inline-formula>\n                     <g:math xmlns:g=\"http:\/\/www.w3.org\/1998\/Math\/MathML\" id=\"M4\">\n                        <g:mn>2.77<\/g:mn>\n                        <g:mo>\u00b1<\/g:mo>\n                        <g:mn>0.97<\/g:mn>\n                     <\/g:math>\n                  <\/jats:inline-formula> vs. <jats:inline-formula>\n                     <i:math xmlns:i=\"http:\/\/www.w3.org\/1998\/Math\/MathML\" id=\"M5\">\n                        <i:mn>1.80<\/i:mn>\n                        <i:mo>\u00b1<\/i:mo>\n                        <i:mn>0.45<\/i:mn>\n                     <\/i:math>\n                  <\/jats:inline-formula> per day, <jats:inline-formula>\n                     <k:math xmlns:k=\"http:\/\/www.w3.org\/1998\/Math\/MathML\" id=\"M6\">\n                        <k:mi>p<\/k:mi>\n                        <k:mo>=<\/k:mo>\n                        <k:mn>0.041<\/k:mn>\n                     <\/k:math>\n                  <\/jats:inline-formula>) than excluded cases. We concluded that gastroenterologists could detect a greater proportion of gastrointestinal symptoms in COVID-19 patients during fever clinic inquiries. Moreover, confirmed COVID-19 patients are more likely to have higher severity in digestive symptoms than excluded cases. Therefore, physicians in fever clinic should pay more attention to the triage of gastrointestinal symptoms.<\/jats:p>","DOI":"10.1155\/2020\/8853922","type":"journal-article","created":{"date-parts":[[2020,12,8]],"date-time":"2020-12-08T19:29:01Z","timestamp":1607455741000},"page":"1-6","source":"Crossref","is-referenced-by-count":3,"title":["Gastroenterologists Reveal More Digestive Symptoms in COVID-19 Patients than Nongastroenterologists in Fever Clinic"],"prefix":"10.1155","volume":"2020","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-5783-539X","authenticated-orcid":true,"given":"Yudong","family":"Jiang","sequence":"first","affiliation":[{"name":"Division of Gastroenterology, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, 1277 Jiefang Avenue, Wuhan, Hubei Province, 430022, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Chaoqun","family":"Han","sequence":"additional","affiliation":[{"name":"Division of Gastroenterology, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, 1277 Jiefang Avenue, Wuhan, Hubei Province, 430022, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Tao","family":"Bai","sequence":"additional","affiliation":[{"name":"Division of Gastroenterology, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, 1277 Jiefang Avenue, Wuhan, Hubei Province, 430022, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Shengyan","family":"Zhang","sequence":"additional","affiliation":[{"name":"Division of Gastroenterology, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, 1277 Jiefang Avenue, Wuhan, Hubei Province, 430022, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jun","family":"Song","sequence":"additional","affiliation":[{"name":"Division of Gastroenterology, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, 1277 Jiefang Avenue, Wuhan, Hubei Province, 430022, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3694-2126","authenticated-orcid":true,"given":"Xiaohua","family":"Hou","sequence":"additional","affiliation":[{"name":"Division of Gastroenterology, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, 1277 Jiefang Avenue, Wuhan, Hubei Province, 430022, China"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","reference":[{"key":"1","doi-asserted-by":"publisher","DOI":"10.1080\/22221751.2020.1725399"},{"key":"2","doi-asserted-by":"publisher","DOI":"10.1126\/science.abb3221"},{"key":"3","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(20)30183-5"},{"key":"4","doi-asserted-by":"publisher","DOI":"10.1148\/radiol.2020200241"},{"key":"5","doi-asserted-by":"publisher","DOI":"10.14309\/ajg.0000000000000610"},{"key":"6","doi-asserted-by":"publisher","DOI":"10.1053\/j.gastro.2020.02.054"},{"key":"7","doi-asserted-by":"publisher","DOI":"10.1053\/j.gastro.2020.02.055"},{"key":"8","doi-asserted-by":"publisher","DOI":"10.14309\/ajg.0000000000000664"},{"key":"9","article-title":"Clinical management of severe acute respiratory infection when novel coronavirus (2019-nCoV) infection is suspected: interim guidance","volume-title":"Portal Regional da BVS","author":"Organization WH","year":"2020"},{"volume-title":"Diagnosis and treatment scheme of new coronavirus infected pneumonia (trial version 6)","year":"2020","author":"China NHCo","key":"10"},{"issue":"1","key":"11","doi-asserted-by":"crossref","first-page":"4","DOI":"10.1186\/s40779-020-0233-6","article-title":"A rapid advice guideline for the diagnosis and treatment of 2019 novel coronavirus (2019-nCoV) infected pneumonia (standard version)","volume":"7","author":"Y. H. Jin","year":"2020","journal-title":"Military Medical Research"},{"key":"12","doi-asserted-by":"publisher","DOI":"10.1038\/s41586-020-2012-7"},{"key":"13","doi-asserted-by":"publisher","DOI":"10.14309\/ajg.0000000000000620"},{"key":"14","doi-asserted-by":"publisher","DOI":"10.3390\/v12050491"},{"key":"15","doi-asserted-by":"crossref","first-page":"76","DOI":"10.1038\/s41420-020-00307-w","article-title":"Digestive symptoms of COVID-19 and expression of ACE2 in digestive tract organs","volume":"6","author":"J. Xu","year":"2020","journal-title":"Cell Death Discovery"},{"key":"16","doi-asserted-by":"publisher","DOI":"10.1038\/s41398-020-01039-2"}],"container-title":["Gastroenterology Research and Practice"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/downloads.hindawi.com\/journals\/grp\/2020\/8853922.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/downloads.hindawi.com\/journals\/grp\/2020\/8853922.xml","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/downloads.hindawi.com\/journals\/grp\/2020\/8853922.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2020,12,8]],"date-time":"2020-12-08T19:29:06Z","timestamp":1607455746000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.hindawi.com\/journals\/grp\/2020\/8853922\/"}},"subtitle":[],"editor":[{"given":"Greger","family":"Lindberg","sequence":"additional","affiliation":[],"role":[{"role":"editor","vocabulary":"crossref"}]}],"short-title":[],"issued":{"date-parts":[[2020,11,30]]},"references-count":16,"alternative-id":["8853922","8853922"],"URL":"https:\/\/doi.org\/10.1155\/2020\/8853922","relation":{},"ISSN":["1687-630X","1687-6121"],"issn-type":[{"type":"electronic","value":"1687-630X"},{"type":"print","value":"1687-6121"}],"subject":[],"published":{"date-parts":[[2020,11,30]]}}}