{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,27]],"date-time":"2026-06-27T23:29:45Z","timestamp":1782602985745,"version":"3.54.5"},"reference-count":10,"publisher":"Wiley","license":[{"start":{"date-parts":[[2020,12,22]],"date-time":"2020-12-22T00:00:00Z","timestamp":1608595200000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Case Reports in Hepatology"],"published-print":{"date-parts":[[2020,12,22]]},"abstract":"<jats:p>Damage to the liver or kidney can occur through direct toxic effects; however, damage can also be drug-induced immune-mediated. Levamisole-adulterated cocaine (LAC) is known to cause antineutrophil cytoplasmic antibody- (ANCA-) associated vasculitis and glomerulonephritis leading to acute kidney injury and end-stage renal disease. It remains unclear whether LAC is associated with hepatic duct damage. Here, we report a case with biopsy-proven evidence of intrahepatic duct damage months after being diagnosed with ANCA-associated crescentic and sclerosing glomerulonephritis caused by LAC use. This case represents the first report of LAC-induced ANCA-associated hepatic duct cholestasis in the setting of previous LAC-induced ANCA-positive glomerulonephritis.<\/jats:p>","DOI":"10.1155\/2020\/8867183","type":"journal-article","created":{"date-parts":[[2020,12,23]],"date-time":"2020-12-23T19:51:10Z","timestamp":1608753070000},"page":"1-3","source":"Crossref","is-referenced-by-count":4,"title":["ANCA-Associated Intrahepatic Duct Injury Associated with Levamisole-Adulterated Cocaine"],"prefix":"10.1155","volume":"2020","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-6366-0116","authenticated-orcid":true,"given":"Joshua K.","family":"Salabei","sequence":"first","affiliation":[{"name":"University of Central Florida, School of Medicine, 6850 Lake Nona Blvd, Orlando, FL 32827, USA"},{"name":"North Florida Regional Medical Center, 6500 W Newberry Rd, Gainesville, FL 32605, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sara","family":"Khan","sequence":"additional","affiliation":[{"name":"University of Central Florida, School of Medicine, 6850 Lake Nona Blvd, Orlando, FL 32827, USA"},{"name":"North Florida Regional Medical Center, 6500 W Newberry Rd, Gainesville, FL 32605, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Afzal","family":"Khan","sequence":"additional","affiliation":[{"name":"University of Central Florida, School of Medicine, 6850 Lake Nona Blvd, Orlando, FL 32827, USA"},{"name":"North Florida Regional Medical Center, 6500 W Newberry Rd, Gainesville, FL 32605, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zekarias T.","family":"Asnake","sequence":"additional","affiliation":[{"name":"University of Central Florida, School of Medicine, 6850 Lake Nona Blvd, Orlando, FL 32827, USA"},{"name":"North Florida Regional Medical Center, 6500 W Newberry Rd, Gainesville, FL 32605, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Troy J.","family":"Fishman","sequence":"additional","affiliation":[{"name":"University of Central Florida, School of Medicine, 6850 Lake Nona Blvd, Orlando, FL 32827, USA"},{"name":"North Florida Regional Medical Center, 6500 W Newberry Rd, Gainesville, FL 32605, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jonathan D.","family":"Stromas","sequence":"additional","affiliation":[{"name":"University of Central Florida, School of Medicine, 6850 Lake Nona Blvd, Orlando, FL 32827, USA"},{"name":"North Florida Regional Medical Center, 6500 W Newberry Rd, Gainesville, FL 32605, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zeeshan H.","family":"Ismail","sequence":"additional","affiliation":[{"name":"University of Central Florida, School of Medicine, 6850 Lake Nona Blvd, Orlando, FL 32827, USA"},{"name":"North Florida Regional Medical Center, 6500 W Newberry Rd, Gainesville, FL 32605, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"John R.","family":"Leibach","sequence":"additional","affiliation":[{"name":"University of Central Florida, School of Medicine, 6850 Lake Nona Blvd, Orlando, FL 32827, USA"},{"name":"North Florida Regional Medical Center, 6500 W Newberry Rd, Gainesville, FL 32605, 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