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Since its inception, almost half a century ago, nasal continuous positive airway pressure (NCPAP) has evolved to become the primary modality for neonatal respiratory care in both the developed and developing world. Although evidence has demonstrated the effectiveness of low-cost bubble NCPAP in reducing newborn mortality, its widespread use is yet to be seen in resource-constrained settings. Moreover, many tertiary hospitals in developing countries still utilise an inexpensive locally assembled bNCPAP system of unknown efficacy and safety. This review provides a brief overview of the history, physiological benefits, indications, contraindications, and complications of bNCPAP. Evidence regarding the effectiveness of low-cost bNCPAP in the neonatal intensive care unit is also summarised. The article further details a locally assembled bNCPAP system used in resource-constrained settings and highlights the care package for neonates receiving bNCPAP, failure criteria, and strategies for weaning.<\/jats:p>","DOI":"10.1155\/2020\/8871980","type":"journal-article","created":{"date-parts":[[2020,9,16]],"date-time":"2020-09-16T23:56:58Z","timestamp":1600300618000},"page":"1-10","source":"Crossref","is-referenced-by-count":13,"title":["Bubble Nasal Continuous Positive Airway Pressure (bNCPAP): An Effective Low-Cost Intervention for Resource-Constrained Settings"],"prefix":"10.1155","volume":"2020","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-2318-2401","authenticated-orcid":true,"given":"Walufu Ivan","family":"Egesa","sequence":"first","affiliation":[{"name":"Department of Paediatrics and Child Health, Faculty of Clinical Medicine and Dentistry, Kampala International University, P.O. 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