{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,5,14]],"date-time":"2025-05-14T02:38:05Z","timestamp":1747190285253,"version":"3.40.5"},"reference-count":12,"publisher":"Wiley","license":[{"start":{"date-parts":[[2020,9,29]],"date-time":"2020-09-29T00:00:00Z","timestamp":1601337600000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Case Reports in Surgery"],"published-print":{"date-parts":[[2020,9,29]]},"abstract":"<jats:p>Primary ampullary neoplasms have origin in the ampulla of Vater, an anatomical structure where the common bile duct and the pancreatic duct join together as a common channel. It represents &lt;0.5% of all gastrointestinal cancers and approximately 7% of all periampullary cancers. The adenocarcinomas arising in this region originate from different epithelial cellular constituents present at the site, the histopathological classification encompass: intestinal type, pancreaticobiliary type, and mixed type. Pancreaticoduodenectomy is the treatment of choice when there is an overt or highly suspicious malignant behaviour. We present here the case of a 74-year-old male patient who presented to our department for further investigation of obstructive jaundice and a pancreatic mass associated with a six-month history of significant weight loss and mild epigastric pain. Eventually, a total splenopancreatectomy was performed given the extension of structural anomalies of the organ secondary to an ampullary adenocarcinoma.<\/jats:p>","DOI":"10.1155\/2020\/8879609","type":"journal-article","created":{"date-parts":[[2020,10,1]],"date-time":"2020-10-01T01:05:33Z","timestamp":1601514333000},"page":"1-5","source":"Crossref","is-referenced-by-count":0,"title":["Total Pancreatectomy for Ampullary Adenocarcinoma in a 74-Year-Old Patient: Case Report and Literature Review"],"prefix":"10.1155","volume":"2020","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-3807-908X","authenticated-orcid":true,"given":"Gabriela A.","family":"Arroyo Murillo","sequence":"first","affiliation":[{"name":"General Surgery and Organ Transplantation Unit, Department of Surgery, University of Rome La Sapienza, Rome, Italy"},{"name":"General Surgery and Bariatric Surgery Unit, Department of Surgery, Civita Castellana Hospital, Civita Castellana, Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Eleonore","family":"Choppin De Janvry","sequence":"additional","affiliation":[{"name":"General Surgery and Organ Transplantation Unit, Department of Surgery, University of Rome La Sapienza, Rome, Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Manuela","family":"Garofalo","sequence":"additional","affiliation":[{"name":"General Surgery and Organ Transplantation Unit, Department of Surgery, University of Rome La Sapienza, Rome, Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Fatima","family":"Della Pietra","sequence":"additional","affiliation":[{"name":"General Surgery and Organ Transplantation Unit, Department of Surgery, University of Rome La Sapienza, Rome, Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","reference":[{"key":"1","doi-asserted-by":"publisher","DOI":"10.1002\/jso.21374"},{"key":"2","doi-asserted-by":"publisher","DOI":"10.1016\/j.celrep.2015.12.005"},{"key":"3","doi-asserted-by":"publisher","DOI":"10.1002\/jso.22090"},{"key":"4","doi-asserted-by":"publisher","DOI":"10.1007\/s00534-004-0898-3"},{"key":"5","doi-asserted-by":"publisher","DOI":"10.1097\/PAS.0000000000000230"},{"issue":"2","key":"6","doi-asserted-by":"crossref","first-page":"322","DOI":"10.1002\/jso.25808","article-title":"Impact of adjuvant chemotherapy regimen on survival outcomes in immunohistochemical subtypes of ampullary carcinoma","volume":"121","author":"A. 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Iyegha","year":"2012","journal-title":"Journal of the Pancreas: JOP"},{"key":"12","doi-asserted-by":"publisher","DOI":"10.1097\/MOG.0000000000000458"}],"container-title":["Case Reports in Surgery"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/downloads.hindawi.com\/journals\/cris\/2020\/8879609.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/downloads.hindawi.com\/journals\/cris\/2020\/8879609.xml","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/downloads.hindawi.com\/journals\/cris\/2020\/8879609.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2020,10,1]],"date-time":"2020-10-01T01:05:40Z","timestamp":1601514340000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.hindawi.com\/journals\/cris\/2020\/8879609\/"}},"subtitle":[],"editor":[{"given":"Shin ichi","family":"Kosugi","sequence":"additional","affiliation":[],"role":[{"role":"editor","vocabulary":"crossref"}]}],"short-title":[],"issued":{"date-parts":[[2020,9,29]]},"references-count":12,"alternative-id":["8879609","8879609"],"URL":"https:\/\/doi.org\/10.1155\/2020\/8879609","relation":{},"ISSN":["2090-6919","2090-6900"],"issn-type":[{"type":"electronic","value":"2090-6919"},{"type":"print","value":"2090-6900"}],"subject":[],"published":{"date-parts":[[2020,9,29]]}}}