{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,11,13]],"date-time":"2025-11-13T18:27:41Z","timestamp":1763058461070,"version":"3.41.2"},"reference-count":42,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2020,10,23]],"date-time":"2020-10-23T00:00:00Z","timestamp":1603411200000},"content-version":"vor","delay-in-days":296,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"name":"Shanghai Changning District","award":["20164Y013","CNKW2018Y23"],"award-info":[{"award-number":["20164Y013","CNKW2018Y23"]}]},{"name":"Shanghai Changning Health and Family Planning Commission","award":["20164Y013","CNKW2018Y23"],"award-info":[{"award-number":["20164Y013","CNKW2018Y23"]}]},{"name":"Shanghai Changning District Science and Technology Commission","award":["20164Y013","CNKW2018Y23"],"award-info":[{"award-number":["20164Y013","CNKW2018Y23"]}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["BioMed Research International"],"published-print":{"date-parts":[[2020,1]]},"abstract":"<jats:p><jats:italic>Background<\/jats:italic>. The cross\u2010sectional study is aimed at investigating the relationship between cortisol, testosterone, and metabolic characteristics among male schizophrenics. <jats:italic>Methods<\/jats:italic>. 174 patients were grouped based on their risk of metabolic syndrome (MetS) into the non\u2010MetS, high\u2010risk\u2010MetS (HR\u2010MetS), or MetS groups. Metabolic indices (body mass index (BMI), mean arterial pressure (MAP), cholesterol, triglyceride, and fasting blood glucose (FBG)) were associated with cortisol and testosterone levels using correlation analysis. Multiple linear regression analysis was used to associate the correlations between the WHO Quality of Life\u2013BREF (WHOQOL\u2013BREF) score and the five metabolic indices. <jats:italic>Results<\/jats:italic>. The WHOQOL\u2013BREF score for the non\u2010MetS group significantly differed from the scores of the HR\u2010MetS and MetS groups. The triglyceride level was positively correlated with the cortisol level, while all five metabolic indices were negatively correlated with testosterone level. Stepwise regression analysis produced a model predicting WHOQOL\u2013BREF scores with four variables including MAP, intelligence quotient (IQ), FBG, and age. The correlation analysis then showed that there was a weak linear correlation between the testosterone level and all five metabolic indices. <jats:italic>Conclusions<\/jats:italic>. Among the five metabolic indices, the risks of hypertension and hyperglycemia are correlated with the quality of life in male schizophrenics rather than those of obesity or hyperlipidemia.<\/jats:p>","DOI":"10.1155\/2020\/9124520","type":"journal-article","created":{"date-parts":[[2020,10,24]],"date-time":"2020-10-24T07:45:04Z","timestamp":1603525504000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":6,"title":["The Relationship of Functional Status of Cortisol, Testosterone, and Parameters of Metabolic Syndrome in Male Schizophrenics"],"prefix":"10.1155","volume":"2020","author":[{"given":"Yi","family":"Han","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Haifeng","family":"Ji","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Li","family":"Liu","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4686-8887","authenticated-orcid":false,"given":"Yuncheng","family":"Zhu","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9739-7152","authenticated-orcid":false,"given":"Xixi","family":"Jiang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2020,10,23]]},"reference":[{"key":"e_1_2_13_1_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.pnpbp.2012.09.016"},{"key":"e_1_2_13_2_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.schres.2011.06.008"},{"key":"e_1_2_13_3_2","first-page":"S504","article-title":"Hypothalamus-pituitary-adrenal axis, hair cortisol and the metabolic syndrome","volume":"27","author":"Gaete H. 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