{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,23]],"date-time":"2026-08-23T18:23:17Z","timestamp":1787509397551,"version":"build-2736575974"},"reference-count":17,"publisher":"Wiley","license":[{"start":{"date-parts":[[2020,2,11]],"date-time":"2020-02-11T00:00:00Z","timestamp":1581379200000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Advances in Hematology"],"published-print":{"date-parts":[[2020,2,11]]},"abstract":"<jats:p>\n                    <jats:italic>Background<\/jats:italic>\n                    . Malaria is known to cause severe health consequences due to its marked effects and alteration on the haematological parameters of infected individuals. This study evaluated the haematological profile of adult individuals infected with the malaria parasite.\n                    <jats:italic>Methods<\/jats:italic>\n                    . A retrospective study was conducted using archived data of malaria positive cases from January 2017 to March 15, 2019. Data retrieved included subjects\u2019 demographics, malaria parasite count, malaria parasite species, and full blood count parameters. A total of 236 malaria positive subjects were included in the study.\n                    <jats:italic>Results<\/jats:italic>\n                    . The study showed that more females were infected with the malaria parasite than males (69.07% and 30.93%, respectively). A total of 87.3% of the study population were infected with\n                    <jats:italic>Plasmodium falciparum<\/jats:italic>\n                    as compared to 12.7% infected with\n                    <jats:italic>Plasmodium malariae<\/jats:italic>\n                    . The commonest haematological abnormalities that were seen in this study were lymphopenia (56.78%), anaemia (55.51%), thrombocytopenia (47.46%), eosinopenia (45.76%), neutropenia (29.24%), monocytosis (21.19%), and leucocytosis (17.37%) in the infected subjects. The mean platelet count of\n                    <jats:italic>P. falciparum<\/jats:italic>\n                    -infected subjects was decreased as compared to the mean platelet count of\n                    <jats:italic>P. malariae<\/jats:italic>\n                    -infected subjects. There was a significant (\n                    <mml:math xmlns:mml=\"http:\/\/www.w3.org\/1998\/Math\/MathML\" id=\"M1\">\n                      <mml:mi>P<\/mml:mi>\n                    <\/mml:math>\n                    value &lt;0.05) decrease in the number of platelet count with every unit increase in parasite density.\n                    <jats:italic>Conclusion<\/jats:italic>\n                    . Study participants infected with malaria demonstrated vital changes in haematological parameters with anaemia, thrombocytopenia, lymphopenia, monocytosis, and eosinopenia being the most important predictors of malaria infection especially with\n                    <jats:italic>P. falciparum<\/jats:italic>\n                    species.\n                  <\/jats:p>","DOI":"10.1155\/2020\/9369758","type":"journal-article","created":{"date-parts":[[2020,2,11]],"date-time":"2020-02-11T18:31:57Z","timestamp":1581445917000},"page":"1-6","source":"Crossref","is-referenced-by-count":20,"title":["Haematological Profile of Adults with Malaria Parasitaemia Visiting the Volta Regional Hospital, Ghana"],"prefix":"10.1155","volume":"2020","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-1842-1407","authenticated-orcid":true,"given":"Daniel","family":"Sakzabre","sequence":"first","affiliation":[{"name":"Department of Medical Laboratory Sciences, School of Allied Health Sciences, University of Health and Allied Sciences, Ho, Ghana"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7910-3704","authenticated-orcid":true,"given":"Emmanuel Akomanin","family":"Asiamah","sequence":"additional","affiliation":[{"name":"Department of Medical Laboratory Sciences, School of Allied Health Sciences, University of Health and Allied Sciences, Ho, Ghana"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Elliot Elikplim","family":"Akorsu","sequence":"additional","affiliation":[{"name":"Department of Medical Laboratory Sciences, School of Allied Health Sciences, University of Health and Allied Sciences, Ho, Ghana"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1819-0223","authenticated-orcid":true,"given":"Albert","family":"Abaka-Yawson","sequence":"additional","affiliation":[{"name":"Department of Medical Laboratory Sciences, School of Allied Health Sciences, University of Health and Allied Sciences, Ho, Ghana"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Noble Dei","family":"Dika","sequence":"additional","affiliation":[{"name":"Laboratory Department, Volta Regional Hospital, Ho, Ghana"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8000-8990","authenticated-orcid":true,"given":"David Annor","family":"Kwasie","sequence":"additional","affiliation":[{"name":"Laboratory Department, Volta Regional Hospital, Ho, Ghana"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8460-0868","authenticated-orcid":true,"given":"Emmanuel","family":"Ativi","sequence":"additional","affiliation":[{"name":"Department of Medical Laboratory Sciences, School of Allied Health Sciences, University of Health and Allied Sciences, Ho, Ghana"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Confidence","family":"Tseyiboe","sequence":"additional","affiliation":[{"name":"Department of Medical Laboratory Sciences, School of Allied Health Sciences, University of Health and Allied Sciences, Ho, Ghana"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"George Yiadom","family":"Osei","sequence":"additional","affiliation":[{"name":"Department of Medical Laboratory Sciences, School of Allied Health Sciences, University of Health and Allied Sciences, Ho, Ghana"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","reference":[{"key":"1","doi-asserted-by":"publisher","DOI":"10.5539\/gjhs.v4n4p139"},{"issue":"2","key":"2","first-page":"57","volume":"1","year":"2014","journal-title":"International Journal of Clinical Medicine 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