{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,29]],"date-time":"2026-04-29T03:41:07Z","timestamp":1777434067541,"version":"3.51.4"},"reference-count":33,"publisher":"Wiley","license":[{"start":{"date-parts":[[2020,2,4]],"date-time":"2020-02-04T00:00:00Z","timestamp":1580774400000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"name":"Amhara Regional Health Bureau"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Journal of Parasitology Research"],"published-print":{"date-parts":[[2020,2,4]]},"abstract":"<jats:p><jats:italic>Background<\/jats:italic>. Malaria is a life-threatening disease associated with high morbidity and mortality. Helminths are among the most widespread infectious agents prevalent in tropical and subtropical regions of the developing world. Malaria and soil-transmitted helminthiasis (STHs) are coendemic and major public health problems in Ethiopia. The effects of helminth coinfection on malaria parasitemia remained poorly understood. Therefore, the objective of this study was to assess malaria parasitemia among malaria-monoinfected and malaria-soil-transmitted helminthiasis\u2013coinfected febrile patients attending Sanja Hospital, Northwest Ethiopia. <jats:italic>Methods<\/jats:italic>. A cross-sectional study with parallel groups was conducted to assess malaria parasitemia among malaria-monoinfected and malaria-soil-transmitted helminthiasis\u2013coinfected febrile patients in Sanja Hospital from January to March 2019. Double population proportion formula was used for sample size calculation, and convenient sampling technique was used to select 134 study participants. Data were entered and analyzed by using the Statistical Package for Social Sciences (SPSS) version 20. Descriptive statistics, independent <mml:math xmlns:mml=\"http:\/\/www.w3.org\/1998\/Math\/MathML\" id=\"M1\"><mml:mi>t<\/mml:mi><\/mml:math>-test, and one-way analysis of variance (ANOVA) were performed. A <mml:math xmlns:mml=\"http:\/\/www.w3.org\/1998\/Math\/MathML\" id=\"M2\"><mml:mi>P<\/mml:mi><\/mml:math> value of &lt;0.05 was considered as statistically significant. <jats:italic>Results<\/jats:italic>. From 134 malaria-positive study participants, 67 were malaria-monoinfected and 67 were malaria-STHs\u2013coinfected patients. Out of 67 malaria STHs-coinfected patients, 54 (80.6%) were infected with hookworm followed by <jats:italic>Ascaris lumbricoides<\/jats:italic> 11 (16.4%) and <jats:italic>Strongyloides stercoralis<\/jats:italic> 2 (3%). The mean <jats:italic>Plasmodium<\/jats:italic> parasite density was significantly higher in malaria-STHs\u2013coinfected patients than in patients infected with only <jats:italic>Plasmodium<\/jats:italic> parasites (<mml:math xmlns:mml=\"http:\/\/www.w3.org\/1998\/Math\/MathML\" id=\"M3\"><mml:mi>P<\/mml:mi><mml:mo>=<\/mml:mo><mml:mn>0.027<\/mml:mn><\/mml:math>). The intensities of hookworm infection showed a positive association with <jats:italic>Plasmodium<\/jats:italic> parasite densities (<mml:math xmlns:mml=\"http:\/\/www.w3.org\/1998\/Math\/MathML\" id=\"M4\"><mml:mi>F<\/mml:mi><mml:mo>=<\/mml:mo><mml:mn>6.953<\/mml:mn><\/mml:math>, <mml:math xmlns:mml=\"http:\/\/www.w3.org\/1998\/Math\/MathML\" id=\"M5\"><mml:mi>P<\/mml:mi><mml:mo>=<\/mml:mo><mml:mn>0.002<\/mml:mn><\/mml:math>). <jats:italic>Conclusions<\/jats:italic>. Infections with STHs, especially hookworm, were positively associated with <jats:italic>Plasmodium<\/jats:italic> parasite density. The current study finding also revealed that increased worm burden of hookworm as expressed by egg intensity had significantly increased <jats:italic>Plasmodium<\/jats:italic> parasite density.<\/jats:p>","DOI":"10.1155\/2020\/9891870","type":"journal-article","created":{"date-parts":[[2020,2,4]],"date-time":"2020-02-04T18:30:55Z","timestamp":1580841055000},"page":"1-7","source":"Crossref","is-referenced-by-count":8,"title":["Malaria Parasitemia in Febrile Patients Mono- and Coinfected with Soil-Transmitted Helminthiasis Attending Sanja Hospital, Northwest Ethiopia"],"prefix":"10.1155","volume":"2020","author":[{"given":"Fantahun","family":"Getaneh","sequence":"first","affiliation":[{"name":"Shegaw Mota Hospital, Ethiopia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9362-7504","authenticated-orcid":true,"given":"Ayalew Jejaw","family":"Zeleke","sequence":"additional","affiliation":[{"name":"Department of Medical Parasitology, School of 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