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Seven literature databases were systematically searched for eligible in vitro and clinical trials. Selected articles were screened for biological activity, botanical species, phytochemical composition, study design, and methodological quality. A total of 26 articles were included in the review, of which 21 were in vitro studies and 5 clinical trials. The most promising EOs were obtained from Allium tubeorosum, Cinnamomum cassia, Cinnamomum zeylanicum, and Coriandrum sativum L. Among the phytochemicals, citral and thymol were the most active. Clinical trials indicated that the EOs from Pelargonium graveolens and Zataria multiflora are potentially effective to treat oral candidiasis. Further nonclinical and clinical studies with these EO are warranted to determine their potential use and safety for the treatment of oral candidiasis.<\/jats:p>","DOI":"10.1155\/2021\/1059274","type":"journal-article","created":{"date-parts":[[2021,1,8]],"date-time":"2021-01-08T19:10:42Z","timestamp":1610133042000},"page":"1-16","source":"Crossref","is-referenced-by-count":29,"title":["The Use of Essential Oils and Their Isolated Compounds for the Treatment of Oral Candidiasis: A Literature Review"],"prefix":"10.1155","volume":"2021","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-2980-0867","authenticated-orcid":true,"given":"Elba dos Santos","family":"Ferreira","sequence":"first","affiliation":[{"name":"Health Sciences Center, Federal University of Para\u00edba, Jo\u00e3o Pessoa 58051-970, PB, Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Pedro Luiz","family":"Rosalen","sequence":"additional","affiliation":[{"name":"Federal University of Alfenas, Alfenas, MG, Brazil"},{"name":"Department of Physiological Sciences, Piracicaba Dental School, University of Campinas, Piracicaba, SP, Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bruna","family":"Benso","sequence":"additional","affiliation":[{"name":"Department of Physiological Sciences, Piracicaba Dental School, University of Campinas, Piracicaba, SP, Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Janaina","family":"de C\u00e1ssia Orlandi Sardi","sequence":"additional","affiliation":[{"name":"Federal University of Mato Grosso do Sul, Faculty of Pharmaceutical Sciences, Pioneiros 79070-900, MS, Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2252-0889","authenticated-orcid":true,"given":"Carina","family":"Denny","sequence":"additional","affiliation":[{"name":"Department of Physiological Sciences, Piracicaba Dental School, University of Campinas, Piracicaba, SP, Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Simone","family":"Alves de Sousa","sequence":"additional","affiliation":[{"name":"Department of Clinical and Social Dentistry, Federal University of Para\u00edba, Campus I, Jo\u00e3o Pessoa, PB, Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Felipe","family":"Queiroga Sarmento Guerra","sequence":"additional","affiliation":[{"name":"Pharmaceutical Sciences Department, Health Sciences Center, Federal University of Para\u00edba, Campus I, Jo\u00e3o Pessoa, PB, Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Edeltrudes","family":"de Oliveira Lima","sequence":"additional","affiliation":[{"name":"Pharmaceutical Sciences Department, Health Sciences Center, Federal University of Para\u00edba, Campus I, Jo\u00e3o Pessoa, PB, Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Irlan","family":"Almeida Freires","sequence":"additional","affiliation":[{"name":"Department of Physiological Sciences, Piracicaba Dental School, University of Campinas, Piracicaba, SP, Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ricardo","family":"Dias de Castro","sequence":"additional","affiliation":[{"name":"Department of Clinical and Social Dentistry, Health Sciences Center, Federal University of Para\u00edba, Jo\u00e3o Pessoa, PB, Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","reference":[{"key":"1","doi-asserted-by":"publisher","DOI":"10.1128\/iai.00469-16"},{"key":"2","doi-asserted-by":"publisher","DOI":"10.4317\/jced.51798"},{"issue":"2","key":"3","first-page":"103","article-title":"Determina\u00e7\u00e3o da atividade antif\u00fangica dos \u00f3leos essenciais de Curcuma longa L. 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