{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,18]],"date-time":"2026-10-18T02:38:05Z","timestamp":1792291085346,"version":"4.4.0"},"reference-count":14,"publisher":"Wiley","license":[{"start":{"date-parts":[[2021,12,9]],"date-time":"2021-12-09T00:00:00Z","timestamp":1639008000000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Case Reports in Gastrointestinal Medicine"],"published-print":{"date-parts":[[2021,12,9]]},"abstract":"<jats:p>Meckel\u2019s diverticulum is a true diverticulum consisting of all three layers of the small intestine resulting from incomplete regression of the vitelline duct. While it is often benign, it can present with serious complications such as intussusception, ulceration, torsion, hemorrhage, obstruction, inflammation, and fistula formation. Although it typically presents in infancy and early childhood, it can also manifest much later into adulthood. We report a case of Meckel\u2019s diverticulum complicated by significant bleeding in a 33-year-old female patient. Diagnosis was accomplished with video capsule endoscopy and a technetium-99\u2009m pertechnetate scan. The patient responded well to acid suppression, initially with an H2 blocker and later with a PPI (proton pump inhibitor), and remained asymptomatic for nearly four months in the interim to definitive surgical treatment. Microscopic examination of the resected diverticulum confirmed the presence of ectopic gastric mucosa. A PubMed literature search revealed several similar cases of Meckel\u2019s diverticulum complicated by hemorrhage with a favorable response to H2 blockers and PPIs. While surgical resection remains the mainstay of definitive treatment, medications aimed at acid suppression can delay the need for urgent surgery, allow for diagnostic assessment, and optimize conditions for elective surgical treatment.<\/jats:p>","DOI":"10.1155\/2021\/1381395","type":"journal-article","created":{"date-parts":[[2021,12,9]],"date-time":"2021-12-09T16:35:11Z","timestamp":1639067711000},"page":"1-6","source":"Crossref","is-referenced-by-count":5,"title":["Bleeding Meckel\u2019s Diverticulum in a 33-Year-Old Female Diagnosed with Video Capsule Endoscopy and a Technetium-99\u2009m Pertechnetate Scan with a Favorable Response to H2 Blocker and PPI"],"prefix":"10.1155","volume":"2021","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-6240-0750","authenticated-orcid":true,"given":"Gregor","family":"Krstevski","sequence":"first","affiliation":[{"name":"University Clinic of Gastroenterohepatology, Medical Faculty, Ss. Cyril and Methodius University, Boulevard Mother Teresa 17, Skopje 1000, North Macedonia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3416-4711","authenticated-orcid":true,"given":"Urim","family":"Isahi","sequence":"additional","affiliation":[{"name":"University Clinic of Gastroenterohepatology, Medical Faculty, Ss. Cyril and Methodius University, Boulevard Mother Teresa 17, Skopje 1000, North Macedonia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8682-3408","authenticated-orcid":true,"given":"Vladimir","family":"Andreevski","sequence":"additional","affiliation":[{"name":"University Clinic of Gastroenterohepatology, Medical Faculty, Ss. Cyril and Methodius University, Boulevard Mother Teresa 17, Skopje 1000, North Macedonia"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","reference":[{"key":"1","article-title":"Meckel\u2019s diverticulum","volume-title":"Surgical Treatment: Evidence-Based and Problem-Oriented","author":"A. Stallion","year":"2001"},{"key":"2","volume-title":"Meckel Diverticulum","author":"N. K. Kuwajerwala","year":"2021"},{"key":"3","doi-asserted-by":"publisher","DOI":"10.1097\/MD.0000000000012154"},{"key":"4","doi-asserted-by":"publisher","DOI":"10.1258\/jrsm.99.10.5011"},{"key":"5","doi-asserted-by":"publisher","DOI":"10.17235\/reed.2018.5628\/2018"},{"key":"6","doi-asserted-by":"publisher","DOI":"10.1259\/bjr.20130743"},{"key":"7","doi-asserted-by":"publisher","DOI":"10.1097\/00003246-200206001-00003"},{"key":"8","doi-asserted-by":"publisher","DOI":"10.7326\/0003-4819-88-6-846_3"},{"key":"9","doi-asserted-by":"publisher","DOI":"10.1001\/archsurg.1980.01380010069015"},{"key":"10","doi-asserted-by":"publisher","DOI":"10.1001\/jama.1983.03330340016012"},{"key":"11","doi-asserted-by":"publisher","DOI":"10.1159\/000343593"},{"key":"12","doi-asserted-by":"publisher","DOI":"10.1097\/SMJ.0b013e31802f8110"},{"issue":"p S1369","key":"13","first-page":"111","article-title":"Suspected meckel\u2019s diverticulum as cause of gastrointestinal bleeding in elderly adults","author":"L. F. Ottaviano","year":"2016","journal-title":"American Journal of Gastroenterology"},{"key":"14","doi-asserted-by":"publisher","DOI":"10.1097\/00004836-198704000-00028"}],"container-title":["Case Reports in Gastrointestinal Medicine"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/downloads.hindawi.com\/journals\/crigm\/2021\/1381395.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/downloads.hindawi.com\/journals\/crigm\/2021\/1381395.xml","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/downloads.hindawi.com\/journals\/crigm\/2021\/1381395.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2021,12,9]],"date-time":"2021-12-09T16:35:16Z","timestamp":1639067716000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.hindawi.com\/journals\/crigm\/2021\/1381395\/"}},"subtitle":[],"editor":[{"given":"Haruhiko","family":"Sugimura","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"editor"}]}],"short-title":[],"issued":{"date-parts":[[2021,12,9]]},"references-count":14,"alternative-id":["1381395","1381395"],"URL":"https:\/\/doi.org\/10.1155\/2021\/1381395","relation":{},"ISSN":["2090-6536","2090-6528"],"issn-type":[{"value":"2090-6536","type":"electronic"},{"value":"2090-6528","type":"print"}],"subject":[],"published":{"date-parts":[[2021,12,9]]}}}