{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,17]],"date-time":"2026-06-17T03:07:10Z","timestamp":1781665630404,"version":"3.54.5"},"reference-count":18,"publisher":"Wiley","license":[{"start":{"date-parts":[[2021,12,23]],"date-time":"2021-12-23T00:00:00Z","timestamp":1640217600000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Case Reports in Infectious Diseases"],"published-print":{"date-parts":[[2021,12,23]]},"abstract":"<jats:p>Coronavirus disease 2019 (COVID-19) is a viral respiratory infection caused by the Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2). While SARS-CoV-2 is a leading cause of morbidity and mortality in older adults, COVID-19 also affects newborn infants in nurseries and the Neonatal Intensive Care Units (NICUs). The majority of infected neonates are believed to acquire SARS-CoV-2 by horizontal transmission, and most of them have asymptomatic or mild symptomatic infections. In rare cases, infants with COVID-19 may have severe complications resulting in death. We report a case of COVID-19 in a premature neonate born at 34 weeks gestational age who presented with hypothermia and respiratory distress and subsequently developed clinical and radiological signs of necrotizing enterocolitis (NEC). The neonate received medical management, including antibiotics, suspension of gastric feeds, and intensive NICU support. The neonate\u2019s clinical condition improved without surgical intervention, and after 10\u2009days of antibiotics and gradual reestablishment of gastric feeds, patient health condition returned to normal, and weeks later, he was discharged home. COVID-19 in infants is frequently asymptomatic or associated with mild disease, and in rare cases, it may be associated with severe gastrointestinal complications including NEC.<\/jats:p>","DOI":"10.1155\/2021\/1442447","type":"journal-article","created":{"date-parts":[[2021,12,23]],"date-time":"2021-12-23T22:57:35Z","timestamp":1640300255000},"page":"1-4","source":"Crossref","is-referenced-by-count":2,"title":["Necrotizing Enterocolitis in a 34-Week Premature Infant with COVID-19"],"prefix":"10.1155","volume":"2021","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-0661-2609","authenticated-orcid":true,"given":"Mary K.","family":"Mannix","sequence":"first","affiliation":[{"name":"Division of Infectious Diseases, Department of Pediatrics, University at Buffalo, the State University of NY, Buffalo, NY, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Danielle","family":"Blood","sequence":"additional","affiliation":[{"name":"Sister\u2019s Hospital, Catholic Health System, Buffalo, NY, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5628-5760","authenticated-orcid":true,"given":"Oscar G.","family":"Gomez-Duarte","sequence":"additional","affiliation":[{"name":"Division of Infectious Diseases, Department of Pediatrics, University at Buffalo, the State University of NY, Buffalo, NY, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6409-5788","authenticated-orcid":true,"given":"Lauren","family":"Davidson","sequence":"additional","affiliation":[{"name":"Sister\u2019s Hospital, Catholic Health System, Buffalo, NY, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","reference":[{"key":"1","doi-asserted-by":"publisher","DOI":"10.1001\/jama.2020.12839"},{"key":"2","doi-asserted-by":"publisher","DOI":"10.1136\/archdischild-2020-319837"},{"key":"3","doi-asserted-by":"publisher","DOI":"10.1007\/s00431-020-03684-7"},{"key":"4","doi-asserted-by":"publisher","DOI":"10.3389\/fped.2021.617980"},{"key":"5","doi-asserted-by":"publisher","DOI":"10.1097\/mpg.0000000000002953"},{"key":"6","doi-asserted-by":"publisher","DOI":"10.1093\/tropej\/fmaa059"},{"key":"7","doi-asserted-by":"publisher","DOI":"10.1038\/s41372-020-00874-x"},{"key":"8","doi-asserted-by":"publisher","DOI":"10.1001\/jamapediatrics.2016.2708"},{"key":"9","doi-asserted-by":"publisher","DOI":"10.1186\/s12887-017-0847-3"},{"key":"10","doi-asserted-by":"publisher","DOI":"10.1038\/sj.jp.7211510"},{"key":"11","doi-asserted-by":"publisher","DOI":"10.1097\/inf.0000000000002968"},{"key":"12","doi-asserted-by":"crossref","first-page":"209","DOI":"10.1542\/peds.69.2.209","article-title":"Association of coronavirus infection with neonatal necrotizing enterocolitis","volume":"69","author":"C. 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Suryana","year":"2021","journal-title":"Acta medica Indonesiana"}],"container-title":["Case Reports in Infectious Diseases"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/downloads.hindawi.com\/journals\/criid\/2021\/1442447.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/downloads.hindawi.com\/journals\/criid\/2021\/1442447.xml","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/downloads.hindawi.com\/journals\/criid\/2021\/1442447.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2021,12,23]],"date-time":"2021-12-23T22:57:40Z","timestamp":1640300260000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.hindawi.com\/journals\/criid\/2021\/1442447\/"}},"subtitle":[],"editor":[{"given":"Dawei","family":"Cui","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"editor"}]}],"short-title":[],"issued":{"date-parts":[[2021,12,23]]},"references-count":18,"alternative-id":["1442447","1442447"],"URL":"https:\/\/doi.org\/10.1155\/2021\/1442447","relation":{},"ISSN":["2090-6633","2090-6625"],"issn-type":[{"value":"2090-6633","type":"electronic"},{"value":"2090-6625","type":"print"}],"subject":[],"published":{"date-parts":[[2021,12,23]]}}}