{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,11,7]],"date-time":"2025-11-07T00:10:14Z","timestamp":1762474214764,"version":"build-2065373602"},"reference-count":15,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2021,10,23]],"date-time":"2021-10-23T00:00:00Z","timestamp":1634947200000},"content-version":"vor","delay-in-days":295,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Case Reports in Endocrinology"],"published-print":{"date-parts":[[2021,1]]},"abstract":"<jats:p>Patients with hyperthyroidism or thyrotoxicosis present with an unspecific constellation of signs or symptoms such as palpitations, tremors, weight loss, or diarrhea. In some severe cases, hyperthyroidism can predispose patients to metabolic abnormalities and arrhythmias. Thyrotoxic periodic paralysis (TTP) is a rare, life\u2010threatening complication or variant of hyperthyroidism associated with hypokalemia and muscle weakness that affects young Asian or Hispanic males between 20\u201340 years. TTP is reversible, and the management consists of beta\u2010blockers, antithyroid therapy, and conservative potassium correction to prevent severe cardiovascular events such as ventricular arrhythmias with the improvement of transient muscle paralysis. We present a case of a 21\u2010year\u2010old Hispanic male complaining with symptoms of thyrotoxicosis, marked hypokalemia, and severe generalized muscle weakness. Physicians must be aware of this uncommon complication of thyrotoxicosis called thyrotoxic periodic paralysis (TTP) to avoid potassium overcorrection and all the endocrine associations with this pathology.<\/jats:p>","DOI":"10.1155\/2021\/1776538","type":"journal-article","created":{"date-parts":[[2021,10,23]],"date-time":"2021-10-23T15:20:14Z","timestamp":1635002414000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["An Unusual Presentation of Thyrotoxicosis: Leg Weakness and Hypokalemia in a 21\u2010Year\u2010Old Male"],"prefix":"10.1155","volume":"2021","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-3420-9668","authenticated-orcid":false,"given":"Mario S.","family":"Campana","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Maria","family":"Riofrio","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Raja S.","family":"Jadav","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mattan","family":"Rozenek","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2021,10,23]]},"reference":[{"key":"e_1_2_9_1_2","doi-asserted-by":"publisher","DOI":"10.3390\/diagnostics10050316"},{"key":"e_1_2_9_2_2","doi-asserted-by":"publisher","DOI":"10.1210\/jc.2006-0356"},{"key":"e_1_2_9_3_2","doi-asserted-by":"publisher","DOI":"10.1080\/20009666.2017.1316906"},{"key":"e_1_2_9_4_2","doi-asserted-by":"publisher","DOI":"10.1001\/archinte.159.6.601"},{"key":"e_1_2_9_5_2","doi-asserted-by":"publisher","DOI":"10.12669\/pjms.324.11006"},{"key":"e_1_2_9_6_2","doi-asserted-by":"publisher","DOI":"10.1681\/ASN.2012010046"},{"key":"e_1_2_9_7_2","doi-asserted-by":"publisher","DOI":"10.1002\/mus.880121005"},{"key":"e_1_2_9_8_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jemermed.2003.05.004"},{"key":"e_1_2_9_9_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jcte.2020.100235"},{"key":"e_1_2_9_10_2","doi-asserted-by":"publisher","DOI":"10.1530\/EJE-13-0381"},{"key":"e_1_2_9_11_2","doi-asserted-by":"publisher","DOI":"10.4158\/ACCR-2020-0154"},{"key":"e_1_2_9_12_2","doi-asserted-by":"publisher","DOI":"10.1089\/thy.2011.0493"},{"key":"e_1_2_9_13_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2265.2008.03395.x"},{"key":"e_1_2_9_14_2","doi-asserted-by":"publisher","DOI":"10.1080\/08998280.2006.11928143"},{"key":"e_1_2_9_15_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.cell.2009.12.024"}],"container-title":["Case Reports in Endocrinology"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/downloads.hindawi.com\/journals\/crie\/2021\/1776538.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/downloads.hindawi.com\/journals\/crie\/2021\/1776538.xml","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1155\/2021\/1776538","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,11,7]],"date-time":"2025-11-07T00:06:52Z","timestamp":1762474012000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1155\/2021\/1776538"}},"subtitle":[],"editor":[{"given":"Mihail A.","family":"Boyanov","sequence":"additional","affiliation":[],"role":[{"role":"editor","vocabulary":"crossref"}]}],"short-title":[],"issued":{"date-parts":[[2021,1]]},"references-count":15,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2021,1]]}},"alternative-id":["10.1155\/2021\/1776538"],"URL":"https:\/\/doi.org\/10.1155\/2021\/1776538","archive":["Portico"],"relation":{},"ISSN":["2090-6501","2090-651X"],"issn-type":[{"type":"print","value":"2090-6501"},{"type":"electronic","value":"2090-651X"}],"subject":[],"published":{"date-parts":[[2021,1]]},"assertion":[{"value":"2021-07-23","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2021-10-06","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2021-10-23","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}],"article-number":"1776538"}}