{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,5,14]],"date-time":"2025-05-14T02:39:30Z","timestamp":1747190370586,"version":"3.40.5"},"reference-count":18,"publisher":"Wiley","license":[{"start":{"date-parts":[[2021,8,3]],"date-time":"2021-08-03T00:00:00Z","timestamp":1627948800000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"name":"Suqian Science & Technology Program","award":["S201905"],"award-info":[{"award-number":["S201905"]}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Contrast Media &amp; Molecular Imaging"],"published-print":{"date-parts":[[2021,8,3]]},"abstract":"<jats:p>This paper aimed to explore the clinical value of combined adoption of magnetic resonance diffusion tensor imaging (DTI) and quantitative electroencephalogram (QEEG) in assessing microstructure changes and mild neurocognitive dysfunction in patients with white matter demyelination. 128 cases of white matter demyelination admitted to the hospital from October 2018 to October 2019 were rolled into the research group, and 100 healthy patients physically examined during the same period were rolled into the control (ctrl) group. QEEG and magnetic resonance DTI examinations were performed for all patients. The wave power of \u03b4, \u03b8, \u03b1, and \u03b2 and the ratio of \u03b1\/\u03b8 and (\u03b4\u2009+\u2009\u03b8)\/(\u03b1\u2009+\u2009\u03b2) were recorded. The FA values of white matter fibers in different brain areas were measured, and the Montreal Cognitive Assessment (MoCA) and Addenbrooke Cognitive Evaluation rating (ACE-R) were adopted to assess the neurocognitive function of patients. It was found that the dominant frequency of each brain area in the research group was 8-9\u2009Hz slow \u03b1 wave. In contrast with the ctrl, the \u03b1 wave and \u03b1\/\u03b8 values in the research group were lower, while \u03b8 wave and \u03b4\u2009+\u2009\u03b8\/\u03b1\u2009+\u2009\u03b2 values were higher (<jats:inline-formula>\n                     <a:math xmlns:a=\"http:\/\/www.w3.org\/1998\/Math\/MathML\" id=\"M1\">\n                        <a:mi>P<\/a:mi>\n                        <a:mo>&lt;<\/a:mo>\n                        <a:mn>0.05<\/a:mn>\n                     <\/a:math>\n                  <\/jats:inline-formula>); the scores of ACE-R and MoCA were lower (<jats:inline-formula>\n                     <c:math xmlns:c=\"http:\/\/www.w3.org\/1998\/Math\/MathML\" id=\"M2\">\n                        <c:mi>P<\/c:mi>\n                        <c:mo>&lt;<\/c:mo>\n                        <c:mn>0.01<\/c:mn>\n                     <\/c:math>\n                  <\/jats:inline-formula>); the fractional anisotropy (FA) values of the right frontal lobe white matter (0.335\u2009\u00b1\u20090.068), the left temporal lobe white matter (0.391\u2009\u00b1\u20090.032), and the corpus callosum knee white matter (0.658\u2009\u00b1\u20090.053) were lower (<jats:inline-formula>\n                     <e:math xmlns:e=\"http:\/\/www.w3.org\/1998\/Math\/MathML\" id=\"M3\">\n                        <e:mi>P<\/e:mi>\n                        <e:mo>&lt;<\/e:mo>\n                        <e:mn>0.05<\/e:mn>\n                     <\/e:math>\n                  <\/jats:inline-formula>). The FA values of these three areas were positively correlated with attention and calculation, memory, and memory of MoCA scale, respectively (<jats:inline-formula>\n                     <g:math xmlns:g=\"http:\/\/www.w3.org\/1998\/Math\/MathML\" id=\"M4\">\n                        <g:mi>P<\/g:mi>\n                        <g:mo>&lt;<\/g:mo>\n                        <g:mn>0.05<\/g:mn>\n                     <\/g:math>\n                  <\/jats:inline-formula>). The FA value of the right frontal white matter was positively correlated with the attention and calculation score of the ACE-R scale (<jats:inline-formula>\n                     <i:math xmlns:i=\"http:\/\/www.w3.org\/1998\/Math\/MathML\" id=\"M5\">\n                        <i:mi>P<\/i:mi>\n                        <i:mo>&lt;<\/i:mo>\n                        <i:mn>0.05<\/i:mn>\n                     <\/i:math>\n                  <\/jats:inline-formula>). In conclusion, magnetic resonance DTI combined with QEEG could reflect the microstructural changes of white matter, which may be associated with mild neurocognitive impairment. The primary objective of the study was to explore the clinical value of combined adoption of magnetic resonance DTI and QEEG in assessing microstructure changes and mild neurocognitive dysfunction in patients with white matter demyelination, expected to provide a theoretical basis for the treatment of white matter demyelination.<\/jats:p>","DOI":"10.1155\/2021\/2120130","type":"journal-article","created":{"date-parts":[[2021,8,3]],"date-time":"2021-08-03T23:35:27Z","timestamp":1628033727000},"page":"1-7","source":"Crossref","is-referenced-by-count":0,"title":["Value of Magnetic Resonance Diffusion Tensor Imaging Combined with Quantitative Electroencephalogram in Diagnosis of Neurocognitive Impairment in Patients with White Matter Demyelination"],"prefix":"10.1155","volume":"2021","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-9671-1381","authenticated-orcid":true,"given":"Jun","family":"Li","sequence":"first","affiliation":[{"name":"Department of Neurology, Suqian First People\u2019s Hospital, Suqian 223800, Jiangsu, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0871-5927","authenticated-orcid":true,"given":"Hongtao","family":"Li","sequence":"additional","affiliation":[{"name":"Department of Neurology, Suqian First People\u2019s Hospital, Suqian 223800, Jiangsu, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7288-3672","authenticated-orcid":true,"given":"Yun","family":"Ma","sequence":"additional","affiliation":[{"name":"Department of Neurology, Suqian First People\u2019s Hospital, Suqian 223800, Jiangsu, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4414-9424","authenticated-orcid":true,"given":"Xiaowei","family":"Cai","sequence":"additional","affiliation":[{"name":"Department of Imaging, Suqian First People\u2019s Hospital, Suqian 223800, Jiangsu, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2270-4725","authenticated-orcid":true,"given":"Yinjie","family":"Zhong","sequence":"additional","affiliation":[{"name":"Department of Neurology, Suqian First People\u2019s Hospital, Suqian 223800, Jiangsu, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4165-2809","authenticated-orcid":true,"given":"Chunjie","family":"Song","sequence":"additional","affiliation":[{"name":"Department of Neurology, Suqian First People\u2019s Hospital, Suqian 223800, Jiangsu, China"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","reference":[{"key":"1","doi-asserted-by":"publisher","DOI":"10.1161\/STROKEAHA.117.018101"},{"key":"2","doi-asserted-by":"publisher","DOI":"10.1016\/j.clineuro.2018.02.030"},{"key":"3","doi-asserted-by":"publisher","DOI":"10.1016\/S1474-4422(18)30245-X"},{"key":"4","doi-asserted-by":"publisher","DOI":"10.1016\/j.ejpn.2019.06.003"},{"key":"5","doi-asserted-by":"publisher","DOI":"10.1093\/brain\/awz212"},{"key":"6","doi-asserted-by":"publisher","DOI":"10.1111\/ane.13154"},{"key":"7","doi-asserted-by":"publisher","DOI":"10.1007\/s10877-018-0118-3"},{"key":"8","doi-asserted-by":"publisher","DOI":"10.3233\/JIN-180084"},{"key":"9","doi-asserted-by":"publisher","DOI":"10.23736\/S0390-5616.18.04597-6"},{"key":"10","doi-asserted-by":"publisher","DOI":"10.1016\/j.heliyon.2019.e01481"},{"key":"11","doi-asserted-by":"publisher","DOI":"10.1001\/jamainternmed.2015.2152"},{"key":"12","doi-asserted-by":"publisher","DOI":"10.1186\/s12877-018-0951-8"},{"key":"13","doi-asserted-by":"publisher","DOI":"10.1016\/j.parkreldis.2020.05.007"},{"key":"14","doi-asserted-by":"publisher","DOI":"10.1017\/cjn.2019.47"},{"key":"15","doi-asserted-by":"publisher","DOI":"10.1002\/14651858.CD010803.pub2"},{"key":"16","doi-asserted-by":"publisher","DOI":"10.1016\/j.nrl.2020.08.017"},{"key":"17","doi-asserted-by":"publisher","DOI":"10.1212\/WNL.0000000000006646"},{"key":"18","doi-asserted-by":"publisher","DOI":"10.1016\/j.nicl.2017.09.007"}],"container-title":["Contrast Media &amp; Molecular Imaging"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/downloads.hindawi.com\/journals\/cmmi\/2021\/2120130.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/downloads.hindawi.com\/journals\/cmmi\/2021\/2120130.xml","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/downloads.hindawi.com\/journals\/cmmi\/2021\/2120130.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2021,8,3]],"date-time":"2021-08-03T23:35:33Z","timestamp":1628033733000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.hindawi.com\/journals\/cmmi\/2021\/2120130\/"}},"subtitle":[],"editor":[{"given":"Yuvaraja","family":"Teekaraman","sequence":"additional","affiliation":[],"role":[{"role":"editor","vocabulary":"crossref"}]}],"short-title":[],"issued":{"date-parts":[[2021,8,3]]},"references-count":18,"alternative-id":["2120130","2120130"],"URL":"https:\/\/doi.org\/10.1155\/2021\/2120130","relation":{},"ISSN":["1555-4317","1555-4309"],"issn-type":[{"type":"electronic","value":"1555-4317"},{"type":"print","value":"1555-4309"}],"subject":[],"published":{"date-parts":[[2021,8,3]]}}}