{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,5,14]],"date-time":"2025-05-14T02:40:03Z","timestamp":1747190403617,"version":"3.40.5"},"reference-count":22,"publisher":"Wiley","license":[{"start":{"date-parts":[[2021,12,23]],"date-time":"2021-12-23T00:00:00Z","timestamp":1640217600000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Scientific Programming"],"published-print":{"date-parts":[[2021,12,23]]},"abstract":"This study was to investigate the value of ultrasound technology based on the bilateral filtering noise elimination algorithm in evaluating the neuroprotective effect of monosialoganglioside in ketamine-anesthetized Parkinson\u2019s disease patients. The research subjects were 75 patients with Parkinson\u2019s disease admitted to the hospital. The patients were randomly divided into three groups according to different treatment methods: A (GM1\u2009+\u2009ketamine anesthesia group), B (conventional treatment\u2009+\u2009ketamine anesthesia group), and C (GM1\u2009+\u2009nonketamine anesthesia group), with 25 patients in each group. Twenty-five healthy people with similar general data in the three groups (groups A, B, and C) were also selected as the control group (group D). All patients underwent ultrasonography, and ultrasound images were processed using the bilateral filter noise elimination. Structural similarity (SSIM), mean absolute error (MAE), and peak signal to noise ratio (PSNR) were used to evaluate the treatment effect. Plasma phospholipids, the third part of the PD unified score scale, Montreal cognitive assessment scale, and other indicators were analyzed and compared among the four groups. The bilateral filtering image noise was effectively suppressed, and the edge details were kept well. Some of the weak edges and texture information in the image were eliminated, the visual effect was ideal, and the accuracy of the edges of the picture remained good. The serotonin lipid level in group A was greatly lower than the serum phospholipid level in group B after GM1 treatment (6.55 VS 7.84, \n \n P<\/a:mi>\n <<\/a:mo>\n 0.05<\/a:mn>\n <\/a:math>\n <\/jats:inline-formula>). Compared with that before treatment, the serotonin lipid level of group A patients decreased after the treatment, and the difference was considerable (7.46 VS 6.55, \n \n P<\/c:mi>\n <<\/c:mo>\n 0.05<\/c:mn>\n <\/c:math>\n <\/jats:inline-formula>). In short, GM1 had a protective effect on the nerves of patients with Parkinson\u2019s disease anesthetized by ketamine.<\/jats:p>","DOI":"10.1155\/2021\/2253431","type":"journal-article","created":{"date-parts":[[2021,12,23]],"date-time":"2021-12-23T21:54:48Z","timestamp":1640296488000},"page":"1-8","source":"Crossref","is-referenced-by-count":1,"title":["Neuroprotective Effect of Monosialotetrahexosylganglioside (GM1) on Patients with Parkinson\u2019s Disease Anesthetized by Ketamine under Denoising Algorithm-Based Ultrasound Image Diagnosis"],"prefix":"10.1155","volume":"2021","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-0354-9683","authenticated-orcid":true,"given":"Weili","family":"Wang","sequence":"first","affiliation":[{"name":"Department of Anesthesiology, 909th Hospital of PLA (Affiliated Dongnan Hospital of Xiamen University), Zhangzhou 363600, Fujian, 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