{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,12,31]],"date-time":"2025-12-31T08:07:51Z","timestamp":1767168471455,"version":"build-2238731810"},"reference-count":23,"publisher":"Wiley","license":[{"start":{"date-parts":[[2021,9,18]],"date-time":"2021-09-18T00:00:00Z","timestamp":1631923200000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Evidence-Based Complementary and Alternative Medicine"],"published-print":{"date-parts":[[2021,9,18]]},"abstract":"<jats:p>Angina pectoris (AP) with coronary heart disease (CHD) is one of the common cardiovascular diseases in clinical practice, which can be classified as \u201cchest paralysis\u201d in Chinese medicine according to its symptoms, and it is described in many ancient documents. Ancient Chinese medicine believes that the main pathogenesis of the disease is poor blood flow leading to paralysis of the heart and veins, so it is often treated by activating blood and removing blood stasis. In this study, 120 patients with AP of CHD of Qi stagnation and blood stasis type were randomly divided into the observation (n\u2009=\u200960) and the control group (n\u2009=\u200960). In the control group, basic care, conventional treatment, and unselected copper acupuncture scraping were used, while in the observation group, copper acupuncture scraping was performed at the right time of the heart meridian (11\u2009:\u200900\u201313\u2009:\u200900) on the basis of the control group, and all patients received the treatment for a total duration of 4 weeks. We collected data on the traditional Chinese medical (TCM) syndrome score, frequency and duration of angina attacks, nitroglycerin dosage, inflammatory factor levels, and hematological indices pretreatment and posttreatment in both groups. Patients\u2019 adverse effects during treatment were recorded, and the clinical efficacy and ECG efficacy in both groups were evaluated after 4 weeks. We used SPSS.20 statistical software to statistically analyze the above data, and the results showed that the clinical efficacy and ECG efficacy of the observation group were significantly higher than the control group posttreatment. After treatment, the TCM symptom score, angina attack frequency, attack duration and nitroglycerin dosage, serum interleukin-8 (IL-8), hypersensitive C-reactive protein (hs-CRP), and tumor necrosis factor-\u03b1 (TNF-\u03b1) levels, whole blood viscosity (WBV), plasma viscosity (PV), fibrinogen (FIB), and hematocrit (Hct) were significantly lower in both groups compared with those posttreatment. And the observation group showed a greater decrease when compared with the control group. The results also showed that the overall incidence of adverse reactions was lower in both groups during the treatment period. The above results indicate that while ensuring high safety, the copper stone based on theory of midnight-noon ebb-flow can more effectively improve the symptoms and inflammatory response of the body and reduce the viscosity of the blood in AP with CHD of Qi stagnation and blood stasis, and it has better therapeutic effects.<\/jats:p>","DOI":"10.1155\/2021\/2677696","type":"journal-article","created":{"date-parts":[[2021,9,18]],"date-time":"2021-09-18T18:05:09Z","timestamp":1631988309000},"page":"1-8","source":"Crossref","is-referenced-by-count":4,"title":["Study of Scraping with Copper Stone Based on Theory of Midnight-Noon Ebb-Flow in Angina Pectoris with Coronary Heart Disease of Qi Stagnation and Blood Stasis"],"prefix":"10.1155","volume":"2021","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-4767-1912","authenticated-orcid":true,"given":"Xianwen","family":"Tang","sequence":"first","affiliation":[{"name":"Department of Cardiology, Shenzhen Hospital of Beijing University of Chinese Medicine (Longgang), Shenzhen, Guangdong 518116, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jinguo","family":"Yang","sequence":"additional","affiliation":[{"name":"Department of Cardiology, Shenzhen Hospital of Beijing University of Chinese Medicine (Longgang), Shenzhen, Guangdong 518116, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Zhong","family":"Feng","sequence":"additional","affiliation":[{"name":"Department of Cardiology, Shenzhen Hospital of Beijing University of Chinese Medicine (Longgang), Shenzhen, Guangdong 518116, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jingyu","family":"Piao","sequence":"additional","affiliation":[{"name":"Guangdong Pharmaceutical University, Guangzhou, Guangdong, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Quanhao","family":"Yan","sequence":"additional","affiliation":[{"name":"Department of Cardiology, Shenzhen Hospital of Beijing University of Chinese Medicine (Longgang), Shenzhen, Guangdong 518116, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Chao","family":"Gao","sequence":"additional","affiliation":[{"name":"Department of Cardiology, Shenzhen Hospital of Beijing University of Chinese Medicine (Longgang), Shenzhen, Guangdong 518116, China"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","reference":[{"key":"1","doi-asserted-by":"publisher","DOI":"10.1016\/j.amjcard.2015.11.036"},{"key":"2","doi-asserted-by":"publisher","DOI":"10.1093\/eurheartj\/ehx421"},{"key":"3","doi-asserted-by":"publisher","DOI":"10.1007\/s12013-015-0551-6"},{"key":"4","doi-asserted-by":"publisher","DOI":"10.1186\/s13063-021-05448-6"},{"issue":"9","key":"5","first-page":"1439","article-title":"Optimization of PNS\/TGCO components effect on experimental Qi stagnation and blood stasis type of coronary heart disease with increase-decrease baseline geometric proportion design method","volume":"33","author":"Z. 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