{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,12]],"date-time":"2026-03-12T04:15:55Z","timestamp":1773288955671,"version":"3.50.1"},"reference-count":34,"publisher":"Wiley","license":[{"start":{"date-parts":[[2021,10,19]],"date-time":"2021-10-19T00:00:00Z","timestamp":1634601600000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100009368","name":"Mount Kenya University","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100009368","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100009157","name":"Jomo Kenyatta University of Agriculture and Technology","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100009157","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Evidence-Based Complementary and Alternative Medicine"],"published-print":{"date-parts":[[2021,10,19]]},"abstract":"<jats:p>The mushroom Termitomyces striatus is an edible mushroom that grows wildly and belongs to the family Lyophyllaceae. Studies in the last few decades have demonstrated that mushrooms and their active components have beneficial effects on a variety of biological systems. Some mushrooms do exhibit antibacterial properties. Qualitative phytochemical profile was done on the mushroom Termitomyces striatus to establish the presence of compounds responsible for important biological activities. This study also investigated the effect of Termitomyces striatus extracts on certain bacterial strains that included Escherichia coli and Pseudomonas aeruginosa representing the Gram-negative bacteria and Bacillus subtilis and Staphylococcus aureus representing Gram-positive bacteria. The fungi were represented by Candida albicans and Saccharomyces cerevisiae. The mushroom was collected in western Kenya, air-dried, and crushed into powder, followed by extraction using water, methanol, and dichloromethane (DCM) solvents. Antibacterial and antifungal activities were evaluated using the disc-diffusion method. Qualitative phytochemical screening of the aqueous extract revealed the presence of alkaloids, flavonoids, steroids, sterols, saponins, phenols, carbohydrates, and proteins. The three extracts exhibited antibacterial against tested bacterial strains. The DCM extract revealed higher effects among the bacterial strains tested. The three extracts showed antifungal effects against C. albicans. However, both methanol and aqueous extracts did not inhibit growth of S. cerevisiae. In conclusion, T. striatus extracts are a promising source of novel antimicrobial and antifungal agents.<\/jats:p>","DOI":"10.1155\/2021\/3025848","type":"journal-article","created":{"date-parts":[[2021,10,20]],"date-time":"2021-10-20T17:52:10Z","timestamp":1634752330000},"page":"1-10","source":"Crossref","is-referenced-by-count":19,"title":["Phytochemical Profile and Antimicrobial Activities of Edible Mushroom Termitomyces striatus"],"prefix":"10.1155","volume":"2021","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-7478-7297","authenticated-orcid":true,"given":"Concepta N. W.","family":"Sitati","sequence":"first","affiliation":[{"name":"Department of Biological Sciences, School of Pure and Applied Sciences, Mount Kenya University, P.O. Box 1869-30200, Kitale, Kenya"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kenneth O.","family":"Ogila","sequence":"additional","affiliation":[{"name":"Zoology Department, School of Biological Sciences, Jomo Kenyatta University of Agriculture and Technology, P.O. Box 62000-00200, Nairobi, Kenya"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Rebecca W.","family":"Waihenya","sequence":"additional","affiliation":[{"name":"Zoology Department, School of Biological Sciences, Jomo Kenyatta University of Agriculture and Technology, P.O. Box 62000-00200, Nairobi, Kenya"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Lucy A.","family":"Ochola","sequence":"additional","affiliation":[{"name":"Institute of Primate Research, P.O. 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