{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,15]],"date-time":"2026-10-15T06:01:38Z","timestamp":1792044098656,"version":"4.4.0"},"reference-count":20,"publisher":"Wiley","license":[{"start":{"date-parts":[[2021,12,23]],"date-time":"2021-12-23T00:00:00Z","timestamp":1640217600000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"name":"Pierre Fabre Foundation"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Journal of Skin Cancer"],"published-print":{"date-parts":[[2021,12,23]]},"abstract":"<jats:p>Objective. The aim of this study was to identify the factors associated with skin cancers in people with albinism (PWA) in Togo. Method. This is a retrospective analytical study of the records of PWA examined during five dermatological consultation campaigns from 2019 to 2021. Results. During the study period, 517 PWA were seen. Sixty-four (12.3%) of these PWA had presented with 137 cases of skin cancer. The sex ratio (M\/F) was 0.9. The average age of PWA with skin cancer was 39.69\u2009\u00b1\u200915.61 years and that of PWA without skin cancer was 19.17\u2009\u00b1\u200915.24 years (<jats:inline-formula>\n                     <a:math xmlns:a=\"http:\/\/www.w3.org\/1998\/Math\/MathML\" id=\"M1\">\n                        <a:mi>p<\/a:mi>\n                        <a:mo>\u2264<\/a:mo>\n                        <a:mn>0.001<\/a:mn>\n                     <\/a:math>\n                  <\/jats:inline-formula>). The 137 cases of skin cancers were dominated by basal cell carcinomas (45.9%). These skin cancers were located preferentially in the cephalic region (77 cases; 56.2%), followed by the upper limbs (33 cases; 24.1%). In multivariate analysis, the risk factors for skin cancers in PWA were age over 39 years (<jats:inline-formula>\n                     <c:math xmlns:c=\"http:\/\/www.w3.org\/1998\/Math\/MathML\" id=\"M2\">\n                        <c:mi>p<\/c:mi>\n                        <c:mo>\u2264<\/c:mo>\n                        <c:mn>0.001<\/c:mn>\n                     <\/c:math>\n                  <\/jats:inline-formula>) and the presence of actinic keratoses (<jats:inline-formula>\n                     <e:math xmlns:e=\"http:\/\/www.w3.org\/1998\/Math\/MathML\" id=\"M3\">\n                        <e:mi>p<\/e:mi>\n                        <e:mo>\u2264<\/e:mo>\n                        <e:mn>0.001<\/e:mn>\n                     <\/e:math>\n                  <\/jats:inline-formula>). In contrast, the presence of ephelides (<jats:inline-formula>\n                     <g:math xmlns:g=\"http:\/\/www.w3.org\/1998\/Math\/MathML\" id=\"M4\">\n                        <g:mi>p<\/g:mi>\n                        <g:mo>=<\/g:mo>\n                        <g:mn>0.018<\/g:mn>\n                     <\/g:math>\n                  <\/jats:inline-formula>) was a protective factor. Conclusion. This study confirms that advanced age and actinic keratoses are risk factors for skin cancer in PWA, in connection with the cumulative role of solar radiation. Its originality lies in the identification of ephelides as a protective factor. The knowledge and consideration of these risk factors will make it possible to optimise strategies for the prevention of skin cancers in PWA.<\/jats:p>","DOI":"10.1155\/2021\/3433493","type":"journal-article","created":{"date-parts":[[2021,12,23]],"date-time":"2021-12-23T19:35:05Z","timestamp":1640288105000},"page":"1-5","source":"Crossref","is-referenced-by-count":8,"title":["Factors Associated with Skin Cancers in People with Albinism in Togo"],"prefix":"10.1155","volume":"2021","author":[{"given":"Abas","family":"Mouhari-Toure","sequence":"first","affiliation":[{"name":"Service de Dermatolgie et IST, CHU Kara, Universit\u00e9 de Kara, Kara, Togo"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sefako Abla","family":"Akakpo","sequence":"additional","affiliation":[{"name":"Service de Dermatolgie et IST, CHU Sylvanus Olympio, Universit\u00e9 de Lom\u00e9, Lom\u00e9, Togo"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Julienne Noude","family":"Teclessou","sequence":"additional","affiliation":[{"name":"Service de Dermatolgie et IST, CHU Campus Universit\u00e9 de Lom\u00e9, Lom\u00e9, Togo"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Piham","family":"Gnossike","sequence":"additional","affiliation":[{"name":"Centre National de Dermatologie de Gbossim\u00e9, Lom\u00e9, Togo"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Saliou","family":"Adam","sequence":"additional","affiliation":[{"name":"Service de Chirurgie Maxillo-faciale et Plastique, CHU Sylvanus Olympio, Universit\u00e9 de Lom\u00e9, Lom\u00e9, Togo"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Garba","family":"Mahamadou","sequence":"additional","affiliation":[{"name":"Service de Dermatolgie et IST, CHU Sylvanus Olympio, Universit\u00e9 de Lom\u00e9, Lom\u00e9, Togo"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Panaw\u00e9","family":"Kassang","sequence":"additional","affiliation":[{"name":"Service de Dermatolgie et IST, CHU Sylvanus Olympio, Universit\u00e9 de Lom\u00e9, Lom\u00e9, Togo"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yvette","family":"Elegbede","sequence":"additional","affiliation":[{"name":"Service de Dermatolgie et IST, Centre Hospitalier R\u00e9gional de Tomd\u00e8, Kara, Togo"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tchin","family":"Darre","sequence":"additional","affiliation":[{"name":"Laboratoire D\u2019anatomie et Cytotologie Pathologique, CHU Sylvanus Olympio, Universit\u00e9 de Lom\u00e9, Lom\u00e9, Togo"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Koussake","family":"Kombate","sequence":"additional","affiliation":[{"name":"Service de Dermatolgie et IST, CHU Campus Universit\u00e9 de Lom\u00e9, Lom\u00e9, Togo"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Palokinam","family":"Pitch\u00e9","sequence":"additional","affiliation":[{"name":"Service de Dermatolgie et IST, CHU Sylvanus Olympio, Universit\u00e9 de Lom\u00e9, Lom\u00e9, Togo"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8889-2693","authenticated-orcid":true,"given":"Bayaki","family":"Saka","sequence":"additional","affiliation":[{"name":"Service de Dermatolgie et IST, CHU Sylvanus Olympio, Universit\u00e9 de Lom\u00e9, Lom\u00e9, Togo"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","reference":[{"key":"1","doi-asserted-by":"publisher","DOI":"10.1046\/j.1468-3083.2003.00767.x"},{"key":"2","volume-title":"Dermatology","author":"J. 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