{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,18]],"date-time":"2026-08-18T01:49:15Z","timestamp":1787017755712,"version":"build-2736575974"},"reference-count":12,"publisher":"Wiley","license":[{"start":{"date-parts":[[2021,12,22]],"date-time":"2021-12-22T00:00:00Z","timestamp":1640131200000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Case Reports in Obstetrics and Gynecology"],"published-print":{"date-parts":[[2021,12,22]]},"abstract":"<jats:p>Primary mediastinal large B cell lymphoma (PMLBCL) is a subtype of non-Hodgkin\u2019s lymphoma which presents rarely in pregnancy. It is an aggressive tumour that is associated with symptoms of superior vena cava (SVC) compression and airway compromise such as dyspnoea, facial and arm swelling, cough, or chest pain. Timely diagnosis is imperative to optimising patient outcomes and reducing both maternal and fetal morbidity and mortality. We report a case of a 33-year-old woman diagnosed with PMLBCL who presented at 33-week gestation with SVC obstruction to 1\u2009mm in diameter. After multidisciplinary team discussion regarding maternal and fetal implications of management options, we proceeded to a caesarean section and initiated chemotherapy postdelivery. Lower segment caesarean section was uncomplicated, and she underwent a cycle of R-CHOEP followed by 5 cycles of DA-EPOCH. Eighteen months since the completion of the chemotherapy, the disease remained in remission.<\/jats:p>","DOI":"10.1155\/2021\/3438230","type":"journal-article","created":{"date-parts":[[2021,12,22]],"date-time":"2021-12-22T11:20:17Z","timestamp":1640172017000},"page":"1-4","source":"Crossref","is-referenced-by-count":5,"title":["A Pregnancy Case of Primary Mediastinal Large B Cell Lymphoma with Superior Vena Cava Syndrome"],"prefix":"10.1155","volume":"2021","author":[{"given":"Lauren","family":"Brownhalls","sequence":"first","affiliation":[{"name":"Women\u2019s and Newborn Services, Royal Brisbane and Women\u2019s Hospital, Herston, Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ann","family":"Gillett","sequence":"additional","affiliation":[{"name":"Department of Hematology, Royal Brisbane and Women\u2019s Hospital, Herston, Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yasmin","family":"Whately","sequence":"additional","affiliation":[{"name":"Department of Anaesthesia, Royal Brisbane and Women\u2019s Hospital, Herston, Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8958-0731","authenticated-orcid":true,"given":"Keisuke","family":"Tanaka","sequence":"additional","affiliation":[{"name":"Women\u2019s and Newborn Services, Royal Brisbane and Women\u2019s Hospital, Herston, Australia"},{"name":"Faculty of Medicine, The University of Queensland, Herston, Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","reference":[{"key":"1","volume-title":"WHO Classification of Tumours of Haematopoietic and Lymphoid Tissues, Revised","author":"S. H. Swerdlow","year":"2017","edition":"4th edition"},{"key":"2","doi-asserted-by":"publisher","DOI":"10.1016\/j.ogc.2005.08.008"},{"key":"3","first-page":"175","article-title":"Mediastinal (thymic) large B0cell lymphoma, in World Health Organization Classification of Tumors","volume-title":"Pathology and Genetics of Tumors of Haemotopoietic and Lymphoid Tissues","author":"P. Banks","year":"2001"},{"key":"4","doi-asserted-by":"publisher","DOI":"10.1634\/theoncologist.2011-0275"},{"key":"5","doi-asserted-by":"publisher","DOI":"10.1155\/2012\/197347"},{"key":"6","doi-asserted-by":"publisher","DOI":"10.1200\/JCO.2001.19.6.1855"},{"key":"7","doi-asserted-by":"publisher","DOI":"10.1182\/asheducation-2008.1.349"},{"key":"8","doi-asserted-by":"publisher","DOI":"10.3109\/10428194.2015.1049168"},{"key":"9","doi-asserted-by":"publisher","DOI":"10.1111\/j.1447-0756.2000.tb01199.x"},{"key":"10","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMcpc0907803"},{"issue":"2","key":"11","first-page":"143","article-title":"Anaesthetic management of caesarean section in a patient with large mediastinal mass","volume":"25","author":"S. Kashif","year":"2015","journal-title":"Journal of the College of Physicians and Surgeons\u2013Pakistan"},{"key":"12","doi-asserted-by":"publisher","DOI":"10.1186\/s40981-017-0098-1"}],"container-title":["Case Reports in Obstetrics and Gynecology"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/downloads.hindawi.com\/journals\/criog\/2021\/3438230.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/downloads.hindawi.com\/journals\/criog\/2021\/3438230.xml","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/downloads.hindawi.com\/journals\/criog\/2021\/3438230.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2021,12,22]],"date-time":"2021-12-22T11:20:21Z","timestamp":1640172021000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.hindawi.com\/journals\/criog\/2021\/3438230\/"}},"subtitle":[],"editor":[{"given":"Manvinder","family":"Singh","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"editor"}]}],"short-title":[],"issued":{"date-parts":[[2021,12,22]]},"references-count":12,"alternative-id":["3438230","3438230"],"URL":"https:\/\/doi.org\/10.1155\/2021\/3438230","relation":{},"ISSN":["2090-6692","2090-6684"],"issn-type":[{"value":"2090-6692","type":"electronic"},{"value":"2090-6684","type":"print"}],"subject":[],"published":{"date-parts":[[2021,12,22]]}}}