{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,20]],"date-time":"2026-09-20T11:58:01Z","timestamp":1789905481033,"version":"4.0.1"},"reference-count":15,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2021,10,5]],"date-time":"2021-10-05T00:00:00Z","timestamp":1633392000000},"content-version":"vor","delay-in-days":277,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2021,1,1]],"date-time":"2021-01-01T00:00:00Z","timestamp":1609459200000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Journal of Ophthalmology"],"published-print":{"date-parts":[[2021,1]]},"abstract":"\n Objective<\/jats:italic>\n . To compare the results and repeatability of the corneal thickness (CT) and epithelial thickness (ET) maps provided by Enhanced Spectral\u2010Domain\u2010Optical Coherence Tomography with those of Spectral\u2010Domain\u2010OCT in normal eyes.\n Methods<\/jats:italic>\n . 30 normal eyes of 30 patients were assessed by 3 trained operators with ESD\u2010OCT and SD\u2010OCT.\n Results<\/jats:italic>\n . The central and minimum ET obtained with both devices were correlated: central ET,\n r<\/jats:italic>\n \u2009=\u20090.86,\n p<\/jats:italic>\n < 0.05; minimum ET,\n r<\/jats:italic>\n \u2009=\u20090.72,\n p<\/jats:italic>\n < 0.05. Compared with SD\u2010OCT, ESD\u2010OCT tended to underestimate these figures by 1.4 and 1.9\u2009\n \u03bc<\/jats:italic>\n m on average. The central and minimum CT obtained with both devices were strongly correlated: central CT,\n r<\/jats:italic>\n \u2009=\u20090.994,\n p<\/jats:italic>\n < 0.05; minimum CT,\n r<\/jats:italic>\n \u2009=\u20090.995,\n p<\/jats:italic>\n < 0.05. ESD\u2010OCT tended to overestimate these figures by 11 and 14\u2009\n \u03bc<\/jats:italic>\n m on average. Repeatability was good for both devices with a mean coefficient of variation of measurements <6% for ET and <2% for CT. Interoperator variability (standard deviation and COV) was significantly higher for ESD\u2010OCT than for SD\u2010OCT for all local epithelial thicknesses and significantly lower for the central CT and several local corneal thicknesses, whereas no significant differences between both technologies were found for the central and minimum ET and the minimum CT.\n Conclusion<\/jats:italic>\n . ESD\u2010OCT and SD\u2010OCT provide reproducible measurements of CT and ET in normal corneas with a strong correlation between both technologies. However, both technologies are not interchangeable when the main thickness parameters (i.e., central and minimum CT and minimum ET) are used for diagnosing early keratoconus or calculating the expected residual stromal bed thickness before corneal refractive surgery or anterior lamellar keratoplasty.\n <\/jats:p>","DOI":"10.1155\/2021\/3444083","type":"journal-article","created":{"date-parts":[[2021,10,5]],"date-time":"2021-10-05T20:53:37Z","timestamp":1633467217000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":19,"title":["Corneal and Epithelial Thickness Mapping: Comparison of Enhanced Spectral\u2010Domain\u2010 and Spectral\u2010Domain\u2010Optical Coherence Tomography"],"prefix":"10.1155","volume":"2021","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-8649-1442","authenticated-orcid":false,"given":"Cristina","family":"Georgeon","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ilanite","family":"Marciano","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Roxane","family":"Cuyaub\u00e8re","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9133-5786","authenticated-orcid":false,"given":"Otman","family":"Sandali","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7505-7798","authenticated-orcid":false,"given":"Nacim","family":"Bouheraoua","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1395-8483","authenticated-orcid":false,"given":"Vincent","family":"Borderie","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2021,10,5]]},"reference":[{"key":"e_1_2_9_1_2","doi-asserted-by":"publisher","DOI":"10.3928\/1081597x-20090610-06"},{"key":"e_1_2_9_2_2","doi-asserted-by":"publisher","DOI":"10.3928\/1081597x-20100218-01"},{"key":"e_1_2_9_3_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.ophtha.2008.08.004"},{"key":"e_1_2_9_4_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jcrs.2014.06.043"},{"key":"e_1_2_9_5_2","doi-asserted-by":"publisher","DOI":"10.3928\/1081597x-20130129-08"},{"key":"e_1_2_9_6_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.ophtha.2013.05.027"},{"key":"e_1_2_9_7_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.ajo.2018.09.008"},{"key":"e_1_2_9_8_2","doi-asserted-by":"publisher","DOI":"10.3928\/1081597x-20190806-03"},{"key":"e_1_2_9_9_2","doi-asserted-by":"publisher","DOI":"10.1097\/opx.0000000000000974"},{"key":"e_1_2_9_10_2","doi-asserted-by":"publisher","DOI":"10.3928\/1081597x-20151207-03"},{"key":"e_1_2_9_11_2","doi-asserted-by":"publisher","DOI":"10.1038\/s41598-020-57926-7"},{"key":"e_1_2_9_12_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.ajo.2019.01.015"},{"key":"e_1_2_9_13_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jcrs.2018.02.015"},{"key":"e_1_2_9_14_2","doi-asserted-by":"publisher","DOI":"10.1097\/opx.0000000000000417"},{"key":"e_1_2_9_15_2","doi-asserted-by":"publisher","DOI":"10.1155\/2016\/1628469"}],"container-title":["Journal 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