{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,2,21]],"date-time":"2025-02-21T19:02:53Z","timestamp":1740164573648,"version":"3.37.3"},"reference-count":26,"publisher":"Wiley","license":[{"start":{"date-parts":[[2021,10,23]],"date-time":"2021-10-23T00:00:00Z","timestamp":1634947200000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/100006733","name":"Indiana University","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100006733","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Case Reports in Pathology"],"published-print":{"date-parts":[[2021,10,23]]},"abstract":"<jats:p>Renal replacement lipomatosis of the kidney is a rare, benign entity in which extensive fibrofatty proliferation of the renal sinus is associated with marked atrophy of the renal parenchyma. It is often associated with calculi or long-standing inflammation. This entity may be confused with a fatty neoplasm of the kidney. A 51-year-old woman with a past medical history of pancreas transplant for type 1 diabetes subsequently developed ureteral stricture. This was initially managed by a nephrostomy tube and nephroureterostomy stenting with periodic exchanges to help restore urine flow; however, the renal function of the kidney progressively declined with recurrent and complicated urinary tract infections. She presented for kidney transplant with right native nephrectomy. Gross examination of the right kidney revealed a 12.8\u2009cm renal sinus lipomatous mass replacing much of the kidney. Microscopically, the mass consisted of mature adipose tissue with fibrous septae and occasional thick-walled vessels with prominent smooth muscle bundles. A rare atypical stromal cell was present, otherwise no significant cytologic atypia or lipoblasts were identified. After excluding fat-predominant angiomyolipoma and well-differentiated liposarcoma, a diagnosis of renal replacement lipomatosis was made. Renal replacement lipomatosis is a benign condition typically associated with a nonfunctioning or poorly functioning kidney often linked to renal calculus disease or chronic renal infection. The presentation in our case was atypical given an absence of associated renal calculus disease. This case is intended to increase awareness of this less commonly encountered entity as it may be confused with a fatty neoplasm of the kidney, some with malignant potential.<\/jats:p>","DOI":"10.1155\/2021\/3640167","type":"journal-article","created":{"date-parts":[[2021,10,23]],"date-time":"2021-10-23T15:05:05Z","timestamp":1635001505000},"page":"1-4","source":"Crossref","is-referenced-by-count":1,"title":["Renal Replacement Lipomatosis Presenting in the Setting of Ureteral Stricture with Absence of Renal Calculus Disease"],"prefix":"10.1155","volume":"2021","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-9603-6731","authenticated-orcid":true,"given":"Katrina","family":"Collins","sequence":"first","affiliation":[{"name":"Department of Pathology, Indiana University, Indianapolis, IN 46202, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Eric","family":"Brocken","sequence":"additional","affiliation":[{"name":"Department of Pathology, Indiana University, Indianapolis, IN 46202, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Laura M.","family":"Warmke","sequence":"additional","affiliation":[{"name":"Department of Pathology, Indiana University, Indianapolis, IN 46202, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Temel","family":"Tirkes","sequence":"additional","affiliation":[{"name":"Department of Radiology and Clinical Sciences, Indiana University, Indianapolis, IN 46202, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Michael","family":"Hwang","sequence":"additional","affiliation":[{"name":"Department of Pathology, Indiana University, Indianapolis, IN 46202, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","reference":[{"key":"1","doi-asserted-by":"publisher","DOI":"10.2214\/ajr.130.6.1087"},{"key":"2","first-page":"690","article-title":"Renal lipomatosis of kidney","volume":"52","author":"A. A. Kutzmann","year":"1931","journal-title":"Surgery, Gynecology & Obstetrics"},{"issue":"3","key":"3","doi-asserted-by":"crossref","first-page":"233","DOI":"10.1001\/jama.1938.02790290019006","article-title":"Fibrous and fatty replacement of renal parenchyma","volume":"111","author":"L. J. Roth","year":"1962","journal-title":"Journal of the American Medical Association"},{"issue":"5","key":"4","doi-asserted-by":"crossref","first-page":"1061","DOI":"10.1177\/028418516300100503","article-title":"Renal fibrolipomatosis","volume":"1","author":"O. 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