{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,9,21]],"date-time":"2025-09-21T17:27:17Z","timestamp":1758475637572,"version":"3.40.5"},"reference-count":35,"publisher":"Wiley","license":[{"start":{"date-parts":[[2021,10,12]],"date-time":"2021-10-12T00:00:00Z","timestamp":1633996800000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Interdisciplinary Perspectives on Infectious Diseases"],"published-print":{"date-parts":[[2021,10,12]]},"abstract":"<jats:p>Despite some cases of severe or critical manifestations of the coronavirus disease 2019 (COVID-19) described among children, the prevalence of this infection in the pediatric population is quite low worldwide, particularly in sub-Saharan Africa. Current data suggest indeed that, independent of the population considered overall, severe and critical cases of COVID-19 are rare among children. This observation prompted us to discuss the possible hypotheses which could explain the low prevalence of COVID-19 among children; amongst others, we discuss (1) immunomodulation by the Bacillus Calmette\u2013Guerin vaccine or by some parasitic infections such as malaria, schistosomiasis, and helminthiasis and (2) cross immunization with other coronaviruses commonly found in the sub-Saharan African setting.<\/jats:p>","DOI":"10.1155\/2021\/4258414","type":"journal-article","created":{"date-parts":[[2021,10,13]],"date-time":"2021-10-13T11:02:38Z","timestamp":1634122958000},"page":"1-5","source":"Crossref","is-referenced-by-count":2,"title":["The COVID-19 Prevalence among Children: Hypotheses for Low Infection Rate and Few Severe Forms among This Age Group in Sub-Saharan Africa"],"prefix":"10.1155","volume":"2021","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-5050-566X","authenticated-orcid":true,"given":"Sylvain Raoul","family":"Simeni 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Eloumba","sequence":"additional","affiliation":[{"name":"Endocrine and Diabetes Unit and National Obesity Centre, Department of Internal Medicine, Yaounde Central Hospital, Yaounde, Cameroon"},{"name":"Department of Biochemistry, Faculty of Medicine and Biomedical Sciences, University of Yaounde I, Yaounde, Cameroon"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6570-3661","authenticated-orcid":true,"given":"Jean Roger","family":"Moulion Tapouh","sequence":"additional","affiliation":[{"name":"The University of Dschang Taskforce for the Elimination of COVID-19 (UNITED#COVID-19), Dschang, Cameroon"},{"name":"Yaounde University Teaching Hospital, Yaounde, Cameroon"},{"name":"Department of Radiology and Medical Imaging, Faculty of Medicine and Pharmaceutical Sciences, University of Dschang, Dschang, 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