{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,1]],"date-time":"2026-10-01T04:21:04Z","timestamp":1790828464303,"version":"4.1.0"},"reference-count":29,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2021,11,24]],"date-time":"2021-11-24T00:00:00Z","timestamp":1637712000000},"content-version":"vor","delay-in-days":327,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"name":"Anyang City Science and Technology Project","award":["2021C01NY007"],"award-info":[{"award-number":["2021C01NY007"]}]},{"name":"Anyang City Science and Technology Project","award":["81801034"],"award-info":[{"award-number":["81801034"]}]},{"DOI":"10.13039\/501100001809","name":"National Nature Science Foundation of China","doi-asserted-by":"crossref","award":["2021C01NY007"],"award-info":[{"award-number":["2021C01NY007"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"crossref"}]},{"DOI":"10.13039\/501100001809","name":"National Nature Science Foundation of China","doi-asserted-by":"crossref","award":["81801034"],"award-info":[{"award-number":["81801034"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"crossref"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["BioMed Research International"],"published-print":{"date-parts":[[2021,1]]},"abstract":"<jats:p><jats:italic>Purpose.<\/jats:italic> The aim of the present prospective study was to evaluate the effect of titanium mesh and concentrated growth factor (CGF) membranes in reconstructing severe labial bone defects during immediate implantation of anterior maxillary tooth. <jats:italic>Methods.<\/jats:italic> Patients with severe defects presenting on the anterior labial bone plate of maxillary were enrolled in this study. During immediate implantation, the titanium mesh was used to maintain the space of bone graft, collagen membrane, and xenograft bone that were used to guide bone regeneration (GBR). Cone beam computed tomography (CBCT) was used to measure the height and the labial bone thickness around the implant at the time of the second stage surgery, 6 months, 1 year, and 2 years after restoration. The pink esthetic score (PES) was used to evaluate the esthetic outcomes after restoration. <jats:italic>Results.<\/jats:italic> 18 patients were enrolled in this study. The survival rate of implants was 100%, and no complication was observed, except for 1 case of titanium mesh exposure which did not affect osteogenesis. In the second stage of surgery, the labial bone was completely reconstructed, and the top of the implant was covered with a small amount of new bone. The thickness of the labial bone was 3.01\u2009mm (\u00b10.23), 2.96\u2009mm (\u00b10.21), 2.93\u2009mm (\u00b10.19), and 2.92\u2009mm (\u00b10.16) at the time of the second stage surgery, 6 months, 1 year, and 2 years after restoration, respectively. The height of the marginal bone around implants was above the top of implant at the time of the second stage surgery and then reduced 0.72\u2009mm (\u00b10.07), 0.91\u2009mm (\u00b10.08), and 0.90\u2009mm (\u00b10.07) at the time point of 6 months, 1 year, and 2 years after restoration, respectively. The changes of bone thickness and height were statistically significant within one year, but stable after one year. The PES values showed the same tendency. <jats:italic>Conclusions.<\/jats:italic> With the limitation of the present prospective study, the combination of titanium mesh and CGF membrane could provide space maintenance for bone augmentation of alveolar bone defects and improve the bone regeneration in patients with severe labial bone defect when immediate implant of anterior maxillary.<\/jats:p>","DOI":"10.1155\/2021\/4754078","type":"journal-article","created":{"date-parts":[[2021,11,24]],"date-time":"2021-11-24T19:05:10Z","timestamp":1637780710000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":15,"title":["Short\u2010Term Evaluation of Guided Bone Reconstruction with Titanium Mesh Membranes and CGF Membranes in Immediate Implantation of Anterior Maxillary Tooth"],"prefix":"10.1155","volume":"2021","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-9134-5367","authenticated-orcid":false,"given":"Xianli","family":"Wang","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6649-175X","authenticated-orcid":false,"given":"Guoqing","family":"Wang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0542-406X","authenticated-orcid":false,"given":"Xibo","family":"Zhao","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6999-5072","authenticated-orcid":false,"given":"Yanchuan","family":"Feng","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5810-5778","authenticated-orcid":false,"given":"Huijuan","family":"Liu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2685-0559","authenticated-orcid":false,"given":"Fang","family":"Li","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2021,11,24]]},"reference":[{"key":"e_1_2_10_1_2","first-page":"348","article-title":"The Tubingen immediate implant in clinical studies","volume":"33","author":"Schulte W.","year":"1978","journal-title":"Deutsche Zahnarztliche Zeitschrift"},{"key":"e_1_2_10_2_2","doi-asserted-by":"publisher","DOI":"10.1111\/jcpe.12571"},{"key":"e_1_2_10_3_2","doi-asserted-by":"publisher","DOI":"10.1111\/prd.12170"},{"key":"e_1_2_10_4_2","doi-asserted-by":"publisher","DOI":"10.11607\/jomi.2014suppl.g3.3"},{"key":"e_1_2_10_5_2","doi-asserted-by":"publisher","DOI":"10.1111\/cid.12854"},{"key":"e_1_2_10_6_2","first-page":"175","article-title":"Immediate implant placement and provisionalization after long-axis root fracture and complete loss of the facial bony lamella","volume":"31","author":"Noelken R.","year":"2011","journal-title":"Internationnal Jounal of Periodontics Restorative Dentistry"},{"key":"e_1_2_10_7_2","first-page":"174","article-title":"Immediate placement and provisionalization of maxillary anterior single implant with guided bone regeneration, connective tissue graft, and coronally positioned flap procedures","volume":"11","author":"Waki T.","year":"2016","journal-title":"International Journal of Esthetic Dentistry"},{"key":"e_1_2_10_8_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jpor.2012.12.001"},{"key":"e_1_2_10_9_2","doi-asserted-by":"publisher","DOI":"10.1007\/s10006-015-0513-6"},{"key":"e_1_2_10_10_2","doi-asserted-by":"publisher","DOI":"10.1111\/cid.12748"},{"key":"e_1_2_10_11_2","doi-asserted-by":"publisher","DOI":"10.1034\/j.1600-0501.1990.010105.x"},{"key":"e_1_2_10_12_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-0501.2005.01193.x"},{"key":"e_1_2_10_13_2","doi-asserted-by":"publisher","DOI":"10.1007\/s10266-017-0298-1"},{"key":"e_1_2_10_14_2","first-page":"89","article-title":"One-stage horizontal guided bone regeneration with autologous bone, anorganic bovine bone and collagen membranes: follow-up of a prospective study 30 months after loading","volume":"11","author":"Meloni S. M.","year":"2018","journal-title":"European Journal of Oral Implantology"},{"key":"e_1_2_10_15_2","doi-asserted-by":"publisher","DOI":"10.1097\/ID.0b013e31825feb16"},{"key":"e_1_2_10_16_2","doi-asserted-by":"publisher","DOI":"10.1902\/jop.1996.67.7.641"},{"key":"e_1_2_10_17_2","first-page":"844","article-title":"Resorbable versus nonresorbable membranes in combination with bio-Oss for guided bone regeneration","volume":"12","author":"Zitzmann N. U.","year":"1997","journal-title":"International Journal of Oral Maxillofacial Implants"},{"key":"e_1_2_10_18_2","doi-asserted-by":"publisher","DOI":"10.3390\/ma12101710"},{"key":"e_1_2_10_19_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijom.2017.04.021"},{"key":"e_1_2_10_20_2","doi-asserted-by":"publisher","DOI":"10.11607\/prd.2447"},{"key":"e_1_2_10_21_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1708-8208.2009.00257.x"},{"key":"e_1_2_10_22_2","doi-asserted-by":"publisher","DOI":"10.1097\/SCS.0000000000000420"},{"key":"e_1_2_10_23_2","doi-asserted-by":"publisher","DOI":"10.1590\/1807-3107bor-2018.vol32.0029"},{"key":"e_1_2_10_24_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.adaj.2019.04.025"},{"key":"e_1_2_10_25_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-0501.2009.01887.x"},{"key":"e_1_2_10_26_2","first-page":"352","article-title":"Clinical study of titanium mesh in conjunction with concentrate growth factors to rebuild severe bone defect of anterior maxilla","volume":"25","author":"Lin H.-Y.","year":"2010","journal-title":"Shanghai Kou Qiang Yi Xue"},{"key":"e_1_2_10_27_2","doi-asserted-by":"publisher","DOI":"10.1186\/s40729-016-0052-4"},{"key":"e_1_2_10_28_2","doi-asserted-by":"publisher","DOI":"10.1186\/s40729-017-0097-z"},{"key":"e_1_2_10_29_2","first-page":"7922","article-title":"Platelet-rich fibrin application in dentistry: a literature review","volume":"8","author":"Borie E.","year":"2015","journal-title":"International Journal of Clinical and Experimental Medicine"}],"container-title":["BioMed Research International"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/downloads.hindawi.com\/journals\/bmri\/2021\/4754078.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/downloads.hindawi.com\/journals\/bmri\/2021\/4754078.xml","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1155\/2021\/4754078","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,12,31]],"date-time":"2024-12-31T12:16:47Z","timestamp":1735647407000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1155\/2021\/4754078"}},"subtitle":[],"editor":[{"given":"Li Wu","family":"Zheng","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"editor"}]}],"short-title":[],"issued":{"date-parts":[[2021,1]]},"references-count":29,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2021,1]]}},"alternative-id":["10.1155\/2021\/4754078"],"URL":"https:\/\/doi.org\/10.1155\/2021\/4754078","archive":["Portico"],"relation":{},"ISSN":["2314-6133","2314-6141"],"issn-type":[{"value":"2314-6133","type":"print"},{"value":"2314-6141","type":"electronic"}],"subject":[],"published":{"date-parts":[[2021,1]]},"assertion":[{"value":"2021-08-05","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2021-10-23","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2021-11-24","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}],"article-number":"4754078"}}