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To evaluate whether hemodynamic factors are risk factors for prognosis in moyamoya disease (MMD). Materials and Methods. The retrospective study reviewed a single-center MMD cohort in Huashan Hospital from August 2017 to January 2020. Stroke events in 30 days and follow-up modified Rankin Scale (mRS) grade were recorded. Systematic assessments with perioperative mean arterial pressure (MAP), red blood cell (RBC) parameters, and fluid management were also conducted. Logistic regressions were applied to evaluate the predictors of worse outcomes. Data was analyzed using SPSS 24.0. Results. Admission to neurological intensive care unit (NICU) totalled about 347 after revascularization surgery. The result showed that the higher the postoperative MAP level (favorable group <jats:inline-formula>\n                     <a:math xmlns:a=\"http:\/\/www.w3.org\/1998\/Math\/MathML\" id=\"M1\">\n                        <a:mn>95.7<\/a:mn>\n                        <a:mo>\u00b1<\/a:mo>\n                        <a:mn>11.4<\/a:mn>\n                     <\/a:math>\n                  <\/jats:inline-formula>\u2009mmHg vs. unfavorable group <jats:inline-formula>\n                     <c:math xmlns:c=\"http:\/\/www.w3.org\/1998\/Math\/MathML\" id=\"M2\">\n                        <c:mn>103.6<\/c:mn>\n                        <c:mo>\u00b1<\/c:mo>\n                        <c:mn>10.4<\/c:mn>\n                     <\/c:math>\n                  <\/jats:inline-formula>\u2009mmHg, <jats:inline-formula>\n                     <e:math xmlns:e=\"http:\/\/www.w3.org\/1998\/Math\/MathML\" id=\"M3\">\n                        <e:mi>p<\/e:mi>\n                        <e:mo>&lt;<\/e:mo>\n                        <e:mn>0.001<\/e:mn>\n                     <\/e:math>\n                  <\/jats:inline-formula>) and the greater the MAP variability (favorable group <jats:inline-formula>\n                     <g:math xmlns:g=\"http:\/\/www.w3.org\/1998\/Math\/MathML\" id=\"M4\">\n                        <g:mn>0.26<\/g:mn>\n                        <g:mo>\u00b1<\/g:mo>\n                        <g:mn>13.2<\/g:mn>\n                     <\/g:math>\n                  <\/jats:inline-formula> vs. unfavorable group <jats:inline-formula>\n                     <i:math xmlns:i=\"http:\/\/www.w3.org\/1998\/Math\/MathML\" id=\"M5\">\n                        <i:mn>7.2<\/i:mn>\n                        <i:mo>\u00b1<\/i:mo>\n                        <i:mn>13.5<\/i:mn>\n                     <\/i:math>\n                  <\/jats:inline-formula>, <jats:inline-formula>\n                     <k:math xmlns:k=\"http:\/\/www.w3.org\/1998\/Math\/MathML\" id=\"M6\">\n                        <k:mi>p<\/k:mi>\n                        <k:mo>=<\/k:mo>\n                        <k:mn>0.006<\/k:mn>\n                     <\/k:math>\n                  <\/jats:inline-formula>) were, the higher the patient\u2019s follow-up mRS grade was. What is more, a higher early postoperative Hb level also seemed to predict a worse long-term clinical outcome (favorable group <jats:inline-formula>\n                     <m:math xmlns:m=\"http:\/\/www.w3.org\/1998\/Math\/MathML\" id=\"M7\">\n                        <m:mn>116.9<\/m:mn>\n                        <m:mo>\u00b1<\/m:mo>\n                        <m:mn>17.1<\/m:mn>\n                     <\/m:math>\n                  <\/jats:inline-formula>\u2009g\/L vs. unfavorable group <jats:inline-formula>\n                     <o:math xmlns:o=\"http:\/\/www.w3.org\/1998\/Math\/MathML\" id=\"M8\">\n                        <o:mn>123.7<\/o:mn>\n                        <o:mo>\u00b1<\/o:mo>\n                        <o:mn>13.0<\/o:mn>\n                     <\/o:math>\n                  <\/jats:inline-formula>\u2009g\/L, <jats:inline-formula>\n                     <q:math xmlns:q=\"http:\/\/www.w3.org\/1998\/Math\/MathML\" id=\"M9\">\n                        <q:mi>p<\/q:mi>\n                        <q:mo>=<\/q:mo>\n                        <q:mn>0.03<\/q:mn>\n                     <\/q:math>\n                  <\/jats:inline-formula>), but the difference disappeared after adjusting sex and age. Logistic regression analyses showed that a higher level of postoperative MAP (<jats:inline-formula>\n                     <s:math xmlns:s=\"http:\/\/www.w3.org\/1998\/Math\/MathML\" id=\"M10\">\n                        <s:mi>\u03b2<\/s:mi>\n                        <s:mo>=<\/s:mo>\n                        <s:mn>0.024<\/s:mn>\n                     <\/s:math>\n                  <\/jats:inline-formula>, 95% CI (0.004, 0.044), and <jats:inline-formula>\n                     <u:math xmlns:u=\"http:\/\/www.w3.org\/1998\/Math\/MathML\" id=\"M11\">\n                        <u:mi>p<\/u:mi>\n                        <u:mo>=<\/u:mo>\n                        <u:mn>0.02<\/u:mn>\n                     <\/u:math>\n                  <\/jats:inline-formula>) within the first 24\u2009h in NICU might be the short-term risk factor. For long-term outcome, a higher level (<jats:inline-formula>\n                     <w:math xmlns:w=\"http:\/\/www.w3.org\/1998\/Math\/MathML\" id=\"M12\">\n                        <w:mi>\u03b2<\/w:mi>\n                        <w:mo>=<\/w:mo>\n                        <w:mn>1.058<\/w:mn>\n                     <\/w:math>\n                  <\/jats:inline-formula>, 95% CI (1.022, 1.096), and <jats:inline-formula>\n                     <y:math xmlns:y=\"http:\/\/www.w3.org\/1998\/Math\/MathML\" id=\"M13\">\n                        <y:mi>p<\/y:mi>\n                        <y:mo>=<\/y:mo>\n                        <y:mn>0.001<\/y:mn>\n                     <\/y:math>\n                  <\/jats:inline-formula>) and a greater variability (<jats:inline-formula>\n                     <ab:math xmlns:ab=\"http:\/\/www.w3.org\/1998\/Math\/MathML\" id=\"M14\">\n                        <ab:mi>\u03b2<\/ab:mi>\n                        <ab:mo>=<\/ab:mo>\n                        <ab:mn>30.982<\/ab:mn>\n                     <\/ab:math>\n                  <\/jats:inline-formula>, 95% CI (2.112, 454.414), and <jats:inline-formula>\n                     <cb:math xmlns:cb=\"http:\/\/www.w3.org\/1998\/Math\/MathML\" id=\"M15\">\n                        <cb:mi>p<\/cb:mi>\n                        <cb:mo>=<\/cb:mo>\n                        <cb:mn>0.01<\/cb:mn>\n                     <\/cb:math>\n                  <\/jats:inline-formula>) of postoperative MAP might be the negative predictors of mRS grade. Conclusions. The early postoperative hemodynamic management might be extremely critical for patients with MMD. Both high postoperative MAP levels and large MAP variability might affect the prognosis. What is more, we also found that a higher postoperative Hb level might be related with a worse outcome.<\/jats:p>","DOI":"10.1155\/2021\/5061173","type":"journal-article","created":{"date-parts":[[2021,10,12]],"date-time":"2021-10-12T15:53:50Z","timestamp":1634054030000},"page":"1-7","source":"Crossref","is-referenced-by-count":4,"title":["The First 24\u2009h Hemodynamic Management in NICU after Revascularization Surgery in Moyamoya Disease"],"prefix":"10.1155","volume":"2021","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-3267-8348","authenticated-orcid":true,"given":"Jie","family":"Song","sequence":"first","affiliation":[{"name":"Department of Neurosurgery, Huashan Hospital, Fudan University, 12 Wulumuqi Zhong Road, Shanghai 200040, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4158-5546","authenticated-orcid":true,"given":"Yu","family":"Lei","sequence":"additional","affiliation":[{"name":"Department of Neurosurgery, Huashan 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