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Although there is a consensus on treatment guidelines for CKD\u2010MBD, it remains uncertain whether these treatment recommendations reflect actual practice. Therefore, the aim of this study was to investigate the CKD\u2010MBD medication trend in real\u2010world practice. This was a retrospective and observational study using a 12\u2010year period database transformed into a common data model from three tertiary university hospitals. Study populations were subjects initially diagnosed as CKD. The date of diagnosis was designated as the index date. New patients were categorized year to year from 2008 to 2019 with a fixed observation period of 365 days to check the prescription of CKD\u2010MBD medications including calcium\u2010containing phosphate binder, noncalcium\u2010containing phosphate binder, aluminium hydroxide, vitamin D receptor activator (VDRA), and cinacalcet. The numbers of CKD patients in the three hospitals were 7555, 2424, and 5351, respectively. The proportion for patients with CKD\u2010MBD medication prescription decreased yearly regardless of hospital and CKD stage (<jats:italic>p<\/jats:italic> for trend &lt; 0.05). The use of aluminium hydroxide disappeared steadily while the use of VDRA increased annually in all settings. Despite these changes in prescription patterns, the mean value for CKD\u2010MBD\u2010related serologic markers was almost within target range. The proportion of the population within the target value was not significantly changed. Irrespective of hospital and CKD stage, similar trends of prescription for CKD\u2010MBD medications were observed in real\u2010world practice. Further research with a distributed network study may be helpful to understand medication trends in CKD\u2010MBD treatment.<\/jats:p>","DOI":"10.1155\/2021\/5504873","type":"journal-article","created":{"date-parts":[[2021,11,23]],"date-time":"2021-11-23T03:05:12Z","timestamp":1637636712000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":2,"title":["Characterization of Medication Trends for Chronic Kidney Disease: Mineral and Bone Disorder Treatment Using Electronic Health Record\u2010Based Common Data 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