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Long noncoding RNAs (lncRNAs) with the length of more than 200\u2009nt functioned importantly in physiological and pathological advancement. Nevertheless, further investigation regarding lncRNA expression feature and function in urologic cancers should be essential. This study is aimed at uncovering the roles of the differently expressed lncRNAs in urologic cancers. The data of gene expression levels was downloaded from lncRNAtor datasets. The lncRNA expression pattern existing in different urologic cancers was assessed by hierarchical clustering analysis. Gene Ontology (GO) analysis and KEGG pathway analysis were separately applied to evaluate the biological function and process and the biological pathways involving differently expressed lncRNAs. Our results indicated that 18 lncRNA expressions were increased, and 16 lncRNA expressions were reduced in urologic cancers after comparison with that in normal tissues. Moreover, our results demonstrated 61, 422, 137, and 281 lncRNAs were specifically dysregulated in bladder cancer (BLCA), kidney renal clear cell cancer (KIRC), kidney renal papillary cell cancer (KIRP), and prostate adenocarcinoma (PRAD), respectively. Bioinformatics analysis showed that differently expressed lncRNAs displayed crucially in urologic cancers. The prognostic value of common and cancer-specific differently expressed lncRNAs, such as PVT1, in cancer outcomes, was emphasized here. Our research has deeply unearthed the mechanism of differently expressed lncRNAs in urologic cancers development.<\/jats:p>","DOI":"10.1155\/2021\/5515218","type":"journal-article","created":{"date-parts":[[2021,7,10]],"date-time":"2021-07-10T19:20:07Z","timestamp":1625944807000},"page":"1-15","source":"Crossref","is-referenced-by-count":6,"title":["Comprehensive Characterization of Common and Cancer-Specific Differently Expressed lncRNAs in Urologic Cancers"],"prefix":"10.1155","volume":"2021","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-1605-4762","authenticated-orcid":true,"given":"You-Ji","family":"Yan","sequence":"first","affiliation":[{"name":"Department of Urology, Jingzhou Central Hospital, The Second Clinical College, Yangtze University, Jingzhou, Hubei 434020, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9416-6671","authenticated-orcid":true,"given":"Ling","family":"Zhang","sequence":"additional","affiliation":[{"name":"Department of Pathology, Wuhan No. 1 Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei Province 430022, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1358-5039","authenticated-orcid":true,"given":"Jia-Jie","family":"Zhou","sequence":"additional","affiliation":[{"name":"Department of Urology, Jingzhou Central Hospital, The Second Clinical College, Yangtze University, Jingzhou, Hubei 434020, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1247-628X","authenticated-orcid":true,"given":"Zhong-Jun","family":"Chen","sequence":"additional","affiliation":[{"name":"Department of Urology, Jingzhou Central Hospital, The Second Clinical College, Yangtze University, Jingzhou, Hubei 434020, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4313-9315","authenticated-orcid":true,"given":"Yi-Xiang","family":"Liao","sequence":"additional","affiliation":[{"name":"Department of Urology, Jingzhou Central Hospital, The Second Clinical College, Yangtze University, Jingzhou, Hubei 434020, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1434-773X","authenticated-orcid":true,"given":"Jin-Min","family":"Zeng","sequence":"additional","affiliation":[{"name":"Department of Urology, Jingzhou Central Hospital, The Second Clinical College, Yangtze University, Jingzhou, Hubei 434020, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8557-8973","authenticated-orcid":true,"given":"Hao","family":"Shen","sequence":"additional","affiliation":[{"name":"Department of Urology, The Central Hospital of Wuhan, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei Province 430014, China"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","reference":[{"key":"1","doi-asserted-by":"publisher","DOI":"10.1093\/hmg\/ddl046"},{"key":"2","doi-asserted-by":"publisher","DOI":"10.1158\/2159-8290.CD-11-0209"},{"key":"3","doi-asserted-by":"publisher","DOI":"10.1158\/0008-5472.CAN-17-0385"},{"key":"4","doi-asserted-by":"publisher","DOI":"10.1093\/nar\/gky214"},{"key":"5","doi-asserted-by":"publisher","DOI":"10.1186\/s12943-020-01277-4"},{"key":"6","doi-asserted-by":"publisher","DOI":"10.1186\/s12943-020-01237-y"},{"key":"7","doi-asserted-by":"publisher","DOI":"10.1186\/s12943-019-1064-5"},{"key":"8","doi-asserted-by":"publisher","DOI":"10.1186\/s12964-020-00691-x"},{"key":"9","doi-asserted-by":"publisher","DOI":"10.3322\/caac.21332"},{"key":"10","doi-asserted-by":"publisher","DOI":"10.3322\/caac.21387"},{"key":"11","doi-asserted-by":"publisher","DOI":"10.3322\/caac.21660"},{"key":"12","doi-asserted-by":"publisher","DOI":"10.14670\/HH-18-159"},{"key":"13","doi-asserted-by":"publisher","DOI":"10.1038\/s41588-018-0120-1"},{"key":"14","doi-asserted-by":"publisher","DOI":"10.1038\/s41467-017-00902-z"},{"key":"15","doi-asserted-by":"publisher","DOI":"10.1172\/JCI96218"},{"key":"16","doi-asserted-by":"publisher","DOI":"10.1016\/j.eururo.2008.01.060"},{"key":"17","doi-asserted-by":"publisher","DOI":"10.1093\/bioinformatics\/btu325"},{"key":"18","doi-asserted-by":"publisher","DOI":"10.1126\/scitranslmed.3003180"},{"key":"19","doi-asserted-by":"publisher","DOI":"10.1016\/j.clinbiochem.2013.10.023"},{"key":"20","doi-asserted-by":"publisher","DOI":"10.1016\/S0090-4295(99)00479-3"},{"key":"21","doi-asserted-by":"publisher","DOI":"10.18632\/oncotarget.11391"},{"issue":"9","key":"22","first-page":"2695","article-title":"DD3(PCA3), a very sensitive and specific marker to detect prostate tumors","volume":"62","author":"J. 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