{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,18]],"date-time":"2026-02-18T04:42:30Z","timestamp":1771389750700,"version":"3.50.1"},"reference-count":23,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2021,8,24]],"date-time":"2021-08-24T00:00:00Z","timestamp":1629763200000},"content-version":"vor","delay-in-days":235,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"name":"Gachon Gil Medical Center","award":["FRD2017-11"],"award-info":[{"award-number":["FRD2017-11"]}]},{"name":"Gachon Gil Medical Center","award":["FRD2019-11-02(3)"],"award-info":[{"award-number":["FRD2019-11-02(3)"]}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["BioMed Research International"],"published-print":{"date-parts":[[2021,1]]},"abstract":"<jats:p>Loss of knee cartilage can cause intense pain at the knee epiphysis and this is one of the most common diseases worldwide. To diagnose this condition, the distance between the femur and tibia is calculated based on X\u2010ray images. Accurate segmentation of the femur and tibia is required to assist in the calculation process. Several studies have investigated the use of automatic knee segmentation to assist in the calculation process, but the results are of limited value owing to the complexity of the knee. To address this problem, this study exploits deep learning for robust segmentation not affected by the environment. In addition, the Taguchi method is applied to optimize the deep learning results. Deep learning architecture, optimizer, and learning rate are considered for the Taguchi table to check the impact and interaction of the results. When the Dilated\u2010Resnet architecture is used with the Adam optimizer and a learning rate of 0.001, dice coefficients of 0.964 and 0.942 are obtained for the femur and tibia for knee segmentation. The implemented procedure and the results of this investigation may be beneficial to help in determining the correct margins for the femur and tibia and can be the basis for developing an automatic diagnosis algorithm for orthopedic diseases.<\/jats:p>","DOI":"10.1155\/2021\/5521009","type":"journal-article","created":{"date-parts":[[2021,8,24]],"date-time":"2021-08-24T20:05:21Z","timestamp":1629835521000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":7,"title":["Using Convolutional Neural Network with Taguchi Parametric Optimization for Knee Segmentation from X\u2010Ray Images"],"prefix":"10.1155","volume":"2021","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-0443-0051","authenticated-orcid":false,"given":"Young Jae","family":"Kim","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Seung Ro","family":"Lee","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3363-0629","authenticated-orcid":false,"given":"Ja-Young","family":"Choi","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9714-6038","authenticated-orcid":false,"given":"Kwang Gi","family":"Kim","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2021,8,24]]},"reference":[{"key":"e_1_2_9_1_2","doi-asserted-by":"publisher","DOI":"10.7812\/TPP\/16-183"},{"key":"e_1_2_9_2_2","doi-asserted-by":"publisher","DOI":"10.1016\/0049-0172(90)90046-I"},{"key":"e_1_2_9_3_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.eclinm.2020.100587"},{"key":"e_1_2_9_4_2","doi-asserted-by":"publisher","DOI":"10.1186\/ar3845"},{"key":"e_1_2_9_5_2","doi-asserted-by":"publisher","DOI":"10.1002\/1529-0131(199808)41:8<1343::AID-ART3>3.0.CO;2-9"},{"key":"e_1_2_9_6_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.joca.2006.11.009"},{"key":"e_1_2_9_7_2","doi-asserted-by":"publisher","DOI":"10.1148\/radiol.11101359"},{"key":"e_1_2_9_8_2","unstructured":"SeiseM. 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