{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,14]],"date-time":"2026-10-14T21:01:46Z","timestamp":1792011706820,"version":"4.4.0"},"reference-count":45,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2021,9,6]],"date-time":"2021-09-06T00:00:00Z","timestamp":1630886400000},"content-version":"vor","delay-in-days":248,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2021,1,1]],"date-time":"2021-01-01T00:00:00Z","timestamp":1609459200000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Journal of Ophthalmology"],"published-print":{"date-parts":[[2021,1]]},"abstract":"<jats:p>\n                    <jats:italic>Purpose<\/jats:italic>\n                    . To evaluate the vessel density (VD) of the radial peripapillary capillary (RPC) network using swept\u2010source optical coherence tomography angiography (SS\u2010OCTA) \u201cen face\u201d images of eyes with chiasmal compression caused by brain tumors before and after decompressive surgery compared with healthy controls.\n                    <jats:italic>Methods<\/jats:italic>\n                    . A cross\u2010sectional study was conducted in 12 patients with chiasmal compression confirmed by neuroimaging. Sixteen healthy participants were also included. All patients with chiasmal compression underwent a neuro\u2010ophthalmological examination one week before and 6\u2009months after brain surgery, including static automated perimetry as well as measurement of the thickness of the retinal nerve fiber layer (RNFL) and the ganglion cell complex (GCC) with spectral\u2010domain optical coherence tomography (SD\u2010OCT). Based on this neuro\u2010ophthalmological examination, the presence of an optic neuropathy (ON) was evaluated. Peripapillary VD was obtained in four sectors on a 6\u2009\u00d7\u20096\u2009mm SS\u2010OCTA image using the Cirrus Plex Elite 9000.\n                    <jats:italic>Results<\/jats:italic>\n                    . Baseline average VD was significantly lower in patients with chiasmal compression and ON than in controls (median: 55.62; interquartile range (IQR): 2.96 vs. 58.53; IQR: 2.02;\n                    <jats:italic>p<\/jats:italic>\n                    = 0.003). This decrease was also found in the temporal, superior, and nasal sectors. Average postoperative VD was decreased in patients with chiasmal compression compared with average preoperative VD (median: 56.16; IQR: 4.07 vs. 57.48; IQR: 3.83;\n                    <jats:italic>p<\/jats:italic>\n                    = 0.004). Preoperative VD was significantly correlated with RNFL, GCC thickness, and visual field defects.\n                    <jats:italic>Conclusions<\/jats:italic>\n                    . The VD of the RPC network was decreased in chiasmal compressive ON, and it was further decreased at 6\u2009months after decompressive surgery.\n                  <\/jats:p>","DOI":"10.1155\/2021\/5531959","type":"journal-article","created":{"date-parts":[[2021,9,6]],"date-time":"2021-09-06T15:06:42Z","timestamp":1630940802000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":14,"title":["Peripapillary Microvascularization Analysis Using Swept\u2010Source Optical Coherence Tomography Angiography in Optic Chiasmal Compression"],"prefix":"10.1155","volume":"2021","author":[{"given":"In\u00e8s","family":"Ben 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