{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,9]],"date-time":"2026-07-09T17:11:22Z","timestamp":1783617082331,"version":"3.55.0"},"reference-count":76,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2021,12,2]],"date-time":"2021-12-02T00:00:00Z","timestamp":1638403200000},"content-version":"vor","delay-in-days":335,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Canadian Journal of Gastroenterology and Hepatology"],"published-print":{"date-parts":[[2021,1]]},"abstract":"<jats:p><jats:italic>Objective<\/jats:italic>. Due to the rarity of recurrent gallstone ileus (RGSI), its epidemiological and clinical features are elusive. With a focus on mortality and the site of impaction, this study consolidates the key clinical characteristics of index GSI (IGSI) and RGSI. <jats:italic>Methods<\/jats:italic>. A meta\u2010analysis of cases reported on RGSI was performed. Risk factors for mortality and site of impaction were examined, and a subgroup analysis was performed for age, sex, and site of impaction (jejunum, ileum, or others). <jats:italic>Results<\/jats:italic>. In the final analysis, 50 (56 individual cases) studies were included. The paired data for the site of impaction was available for 45 patients. Women accounted for 87.3% of all RGSI cases included in the pooled analysis. The median age (interquartile range, IQR) of the patients was 70 (63\u201376) years, and the median time of recurrence (IQR) was 20.5 (8.5\u201395.5) days. The overall mortality rate was 11.8%, without correlation between the mortality rate and age, the time of recurrence, or the site of impaction. The region in which the stone was found in RGSI and IGSI was similar in most cases (<jats:italic>p<\/jats:italic> = 0.002). Logistic regression also revealed a higher probability of stone impaction in the ileum in RGSI if it was the site of impaction in IGSI. In most cases, enterolithotomy was the preferred method. <jats:italic>Conclusions<\/jats:italic>. A high index of suspicion for RGSI should be maintained for older women with a history of GSI. The region where the stone was impacted during IGSI should be investigated first in such patients.<\/jats:p>","DOI":"10.1155\/2021\/5539789","type":"journal-article","created":{"date-parts":[[2021,12,2]],"date-time":"2021-12-02T12:50:23Z","timestamp":1638449423000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":7,"title":["The Regularity of the Site of Impaction in Recurrent Gallstone Ileus: A Systematic Review and Meta\u2010Analysis of Reported Cases"],"prefix":"10.1155","volume":"2021","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-4877-2152","authenticated-orcid":false,"given":"Nasser A. N.","family":"Alzerwi","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bandar","family":"Idrees","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Saeed","family":"Alsareii","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yaser","family":"Aldebasi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Afnan","family":"Alsultan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2021,12,2]]},"reference":[{"key":"e_1_2_10_1_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.amjsurg.2010.02.025"},{"key":"e_1_2_10_2_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.amsu.2018.01.004"},{"key":"e_1_2_10_3_2","doi-asserted-by":"publisher","DOI":"10.1136\/bmjgast-2019-000344"},{"key":"e_1_2_10_4_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.amsu.2015.02.001"},{"key":"e_1_2_10_5_2","doi-asserted-by":"publisher","DOI":"10.1136\/bcr-2014-205795"},{"key":"e_1_2_10_6_2","doi-asserted-by":"publisher","DOI":"10.1136\/bcr-2012-008008"},{"key":"e_1_2_10_7_2","doi-asserted-by":"publisher","DOI":"10.1016\/s1499-3872(12)60224-0"},{"key":"e_1_2_10_8_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1751-2980.2009.00378.x"},{"key":"e_1_2_10_9_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1445-2197.2005.03368.x"},{"key":"e_1_2_10_10_2","first-page":"61","article-title":"Management of gallstone ileus","volume":"32","author":"Syme R. G.","year":"1989","journal-title":"Canadian Journal of Surgery. Journal Canadien de Chirurgie"},{"key":"e_1_2_10_11_2","doi-asserted-by":"publisher","DOI":"10.1259\/0007-1285-54-647-1000"},{"key":"e_1_2_10_12_2","doi-asserted-by":"publisher","DOI":"10.4240\/wjgs.v7.i8.152"},{"key":"e_1_2_10_13_2","doi-asserted-by":"publisher","DOI":"10.1136\/bmj.b2700"},{"key":"e_1_2_10_14_2","doi-asserted-by":"publisher","DOI":"10.1136\/bmjebm-2017-110853"},{"key":"e_1_2_10_15_2","doi-asserted-by":"publisher","DOI":"10.1186\/1752-1947-7-223"},{"key":"e_1_2_10_16_2","doi-asserted-by":"publisher","DOI":"10.1093\/ije\/18.1.50"},{"key":"e_1_2_10_17_2","doi-asserted-by":"publisher","DOI":"10.1007\/s11605-016-3096-0"},{"key":"e_1_2_10_18_2","doi-asserted-by":"publisher","DOI":"10.1155\/2019\/8907068"},{"key":"e_1_2_10_19_2","doi-asserted-by":"publisher","DOI":"10.1080\/00015458.2016.1139828"},{"key":"e_1_2_10_20_2","doi-asserted-by":"publisher","DOI":"10.1272\/jnms.82.300"},{"key":"e_1_2_10_21_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijscr.2015.06.003"},{"key":"e_1_2_10_22_2","doi-asserted-by":"publisher","DOI":"10.1136\/bcr-2013-203345"},{"key":"e_1_2_10_23_2","first-page":"35","article-title":"Recurrent gallstone ileus: case report and literature review","volume":"34","author":"Pronio A.","year":"2013","journal-title":"Il Giornale di Chirurgia"},{"key":"e_1_2_10_24_2","doi-asserted-by":"publisher","DOI":"10.1186\/1752-1947-6-362"},{"key":"e_1_2_10_25_2","doi-asserted-by":"publisher","DOI":"10.3121\/cmr.2012.1079"},{"key":"e_1_2_10_26_2","doi-asserted-by":"publisher","DOI":"10.1177\/000313481007600506"},{"key":"e_1_2_10_27_2","doi-asserted-by":"publisher","DOI":"10.1308\/147870810X12659688851753"},{"key":"e_1_2_10_28_2","doi-asserted-by":"publisher","DOI":"10.4321\/s1130-01082009000300013"},{"key":"e_1_2_10_29_2","doi-asserted-by":"publisher","DOI":"10.1001\/archsurg.143.11.1118"},{"key":"e_1_2_10_30_2","doi-asserted-by":"publisher","DOI":"10.1007\/s10140-005-0448-6"},{"key":"e_1_2_10_31_2","doi-asserted-by":"publisher","DOI":"10.1177\/000313480507101020"},{"key":"e_1_2_10_32_2","doi-asserted-by":"publisher","DOI":"10.1007\/s10140-002-0203-1"},{"key":"e_1_2_10_33_2","doi-asserted-by":"publisher","DOI":"10.1136\/pgmj.72.847.300"},{"key":"e_1_2_10_34_2","doi-asserted-by":"publisher","DOI":"10.1001\/archsurg.1984.01390220075017"},{"key":"e_1_2_10_35_2","doi-asserted-by":"publisher","DOI":"10.1007\/BF01888620"},{"key":"e_1_2_10_36_2","doi-asserted-by":"publisher","DOI":"10.2214\/ajr.133.5.921"},{"key":"e_1_2_10_37_2","doi-asserted-by":"publisher","DOI":"10.1093\/milmed\/135.10.909"},{"key":"e_1_2_10_38_2","doi-asserted-by":"publisher","DOI":"10.1097\/00000658-196803000-00011"},{"key":"e_1_2_10_39_2","doi-asserted-by":"publisher","DOI":"10.1016\/0002-9610(64)90088-1"},{"key":"e_1_2_10_40_2","doi-asserted-by":"publisher","DOI":"10.1001\/jama.1962.03050080037008"},{"key":"e_1_2_10_41_2","doi-asserted-by":"publisher","DOI":"10.1097\/00000658-196112000-00014"},{"key":"e_1_2_10_42_2","doi-asserted-by":"publisher","DOI":"10.1001\/jama.1961.03040190016005"},{"key":"e_1_2_10_43_2","doi-asserted-by":"publisher","DOI":"10.1002\/bjs.18004921404"},{"key":"e_1_2_10_44_2","doi-asserted-by":"publisher","DOI":"10.1136\/pgmj.35.410.673"},{"key":"e_1_2_10_45_2","doi-asserted-by":"publisher","DOI":"10.1016\/0002-9610(58)90929-2"},{"key":"e_1_2_10_46_2","doi-asserted-by":"publisher","DOI":"10.1002\/bjs.18004418705"},{"key":"e_1_2_10_47_2","doi-asserted-by":"publisher","DOI":"10.1001\/archsurg.1953.01260030316005"},{"key":"e_1_2_10_48_2","doi-asserted-by":"publisher","DOI":"10.1136\/bmj.2.4835.544"},{"key":"e_1_2_10_49_2","doi-asserted-by":"publisher","DOI":"10.1001\/archsurg.1952.01260010867017"},{"key":"e_1_2_10_50_2","doi-asserted-by":"publisher","DOI":"10.1136\/bmj.1.4398.555"},{"key":"e_1_2_10_51_2","doi-asserted-by":"publisher","DOI":"10.1016\/s0002-9610(43)90506-9"},{"key":"e_1_2_10_52_2","doi-asserted-by":"publisher","DOI":"10.1097\/00000658-194205000-00002"},{"key":"e_1_2_10_53_2","doi-asserted-by":"publisher","DOI":"10.1056\/nejm194008012230503"},{"key":"e_1_2_10_54_2","doi-asserted-by":"publisher","DOI":"10.1016\/s0002-9610(36)90120-4"},{"key":"e_1_2_10_55_2","doi-asserted-by":"publisher","DOI":"10.1002\/bjs.1800239016"},{"key":"e_1_2_10_56_2","doi-asserted-by":"publisher","DOI":"10.1016\/s0002-9610(32)90843-5"},{"key":"e_1_2_10_57_2","doi-asserted-by":"publisher","DOI":"10.1056\/nejm193209082071006"},{"key":"e_1_2_10_58_2","doi-asserted-by":"publisher","DOI":"10.1097\/00000658-193207000-00013"},{"key":"e_1_2_10_59_2","doi-asserted-by":"publisher","DOI":"10.1136\/pgmj.2.17.65"},{"key":"e_1_2_10_60_2","doi-asserted-by":"publisher","DOI":"10.1016\/s0140-6736(01)01097-2"},{"key":"e_1_2_10_61_2","first-page":"598","article-title":"Stated meeting, held at the Mt. sinai hospital, January 10, 1912","volume":"55","author":"Transactions of the New York Surgical Society","year":"1912","journal-title":"Annals of Surgery"},{"key":"e_1_2_10_62_2","doi-asserted-by":"publisher","DOI":"10.11138\/gchir\/2014.35.9.235"},{"key":"e_1_2_10_63_2","doi-asserted-by":"publisher","DOI":"10.1080\/00015458.2012.11680859"},{"key":"e_1_2_10_64_2","first-page":"335","article-title":"Gallstone ileus after laparoscopic cholecystectomy","volume":"5","author":"Ivanov I.","year":"2012","journal-title":"Journal of Medicine and Life"},{"key":"e_1_2_10_65_2","doi-asserted-by":"publisher","DOI":"10.1007\/s13304-011-0057-8"},{"key":"e_1_2_10_66_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jss.2013.05.027"},{"key":"e_1_2_10_67_2","doi-asserted-by":"publisher","DOI":"10.4240\/wjgs.v8.i11.755"},{"key":"e_1_2_10_68_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1751-2980.2008.00338.x"},{"key":"e_1_2_10_69_2","doi-asserted-by":"publisher","DOI":"10.1097\/md.0000000000008541"},{"key":"e_1_2_10_70_2","doi-asserted-by":"publisher","DOI":"10.1007\/s00595-006-3283-9"},{"key":"e_1_2_10_71_2","first-page":"751","article-title":"[Intestinal obstruction caused by gallstone: report of 5 cases and review of the literature]","volume":"13","author":"He J. J.","year":"2010","journal-title":"Zhonghua Wei Chang Wai ke Za Zhi = Chinese Journal of Gastrointestinal Surgery"},{"key":"e_1_2_10_72_2","doi-asserted-by":"publisher","DOI":"10.12998\/wjcc.v8.i10.2023"},{"key":"e_1_2_10_73_2","first-page":"114","article-title":"Gallstone ileus associated with crohn\u2019s disease","volume":"108","author":"Senofsky G. M.","year":"1990","journal-title":"Surgery"},{"key":"e_1_2_10_74_2","doi-asserted-by":"publisher","DOI":"10.1186\/1752-1947-9-15"},{"key":"e_1_2_10_75_2","first-page":"614","article-title":"Gallstone Ileus with cholecysto-duodenal fistula in an elderly male","volume":"30","author":"Umer S.","year":"2018","journal-title":"Journal of Ayub Medical College, Abbottabad: JAMC"},{"key":"e_1_2_10_76_2","doi-asserted-by":"publisher","DOI":"10.1097\/sla.0b013e31827eefed"}],"container-title":["Canadian Journal of Gastroenterology and Hepatology"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/downloads.hindawi.com\/journals\/cjgh\/2021\/5539789.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/downloads.hindawi.com\/journals\/cjgh\/2021\/5539789.xml","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1155\/2021\/5539789","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,9,25]],"date-time":"2025-09-25T07:43:51Z","timestamp":1758786231000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1155\/2021\/5539789"}},"subtitle":[],"editor":[{"given":"Xingshun","family":"Qi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"editor"}]}],"short-title":[],"issued":{"date-parts":[[2021,1]]},"references-count":76,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2021,1]]}},"alternative-id":["10.1155\/2021\/5539789"],"URL":"https:\/\/doi.org\/10.1155\/2021\/5539789","archive":["Portico"],"relation":{},"ISSN":["2291-2789","2291-2797"],"issn-type":[{"value":"2291-2789","type":"print"},{"value":"2291-2797","type":"electronic"}],"subject":[],"published":{"date-parts":[[2021,1]]},"assertion":[{"value":"2021-02-18","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2021-11-16","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2021-12-02","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}],"article-number":"5539789"}}