{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,28]],"date-time":"2026-04-28T04:42:10Z","timestamp":1777351330042,"version":"3.51.4"},"reference-count":16,"publisher":"Wiley","license":[{"start":{"date-parts":[[2021,3,30]],"date-time":"2021-03-30T00:00:00Z","timestamp":1617062400000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Case Reports in Gastrointestinal Medicine"],"published-print":{"date-parts":[[2021,3,30]]},"abstract":"<jats:p>Helicobacterpylori (H. pylori) is a Gram-negative bacterium that colonizes gastric mucosa and is often transmitted through direct contact with saliva, contaminated food or water, and vomit. The majority of the infected individuals remain asymptomatic for a long period. Infection with H. Pylori often presents with dyspepsia, nausea, frequent belching, bloating, abdominal discomfort, burning abdominal pain, and peptic ulcer. A potential association between H. Pylori and recurrent aphthous stomatitis was previously reported; however, the presence of causative relationship between the two remained controversial. We are presenting a case of recurrent aphthous stomatitis of twenty-four-year history resolved after H. pylori treatment.<\/jats:p>","DOI":"10.1155\/2021\/5543838","type":"journal-article","created":{"date-parts":[[2021,3,30]],"date-time":"2021-03-30T18:56:24Z","timestamp":1617130584000},"page":"1-5","source":"Crossref","is-referenced-by-count":4,"title":["Recurrent Aphthous Stomatitis Improved after Eradication Therapy for Helicobacter pylori"],"prefix":"10.1155","volume":"2021","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-5418-9126","authenticated-orcid":true,"given":"Yinglin","family":"Gao","sequence":"first","affiliation":[{"name":"Internal Medicine, Loma Linda University Medical Center, Loma Linda, CA, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Nikhil","family":"Gupta","sequence":"additional","affiliation":[{"name":"Gastroenterology Department, Loma Linda University Medical Center, Loma Linda, CA, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Maisa","family":"Abdalla","sequence":"additional","affiliation":[{"name":"Gastroenterology Department, Loma Linda University Medical Center, Loma Linda, CA, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","reference":[{"key":"1","doi-asserted-by":"publisher","DOI":"10.4317\/medoral.20872"},{"key":"2","doi-asserted-by":"publisher","DOI":"10.1053\/j.gastro.2017.04.022"},{"key":"3","doi-asserted-by":"publisher","DOI":"10.1086\/315384"},{"key":"4","doi-asserted-by":"publisher","DOI":"10.1016\/j.cden.2013.12.002"},{"key":"5","doi-asserted-by":"publisher","DOI":"10.1016\/j.amjoto.2005.09.022"},{"key":"6","doi-asserted-by":"publisher","DOI":"10.37506\/ijfmt.v14i4.11657"},{"key":"7","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-4632.2008.03667.x.PMID:18477159"},{"key":"8","doi-asserted-by":"crossref","first-page":"89","DOI":"10.1111\/j.1600-0714.2012.01197.x","article-title":"Impact of Helicobacter pylori on the clinical course of recurrent aphthous stomatitis","volume":"42","author":"D. A. Tas","year":"2013","journal-title":"Journal of Oral Pathology & Medicine"},{"key":"9","doi-asserted-by":"publisher","DOI":"10.1007\/s00784-014-1230-5"},{"issue":"12","key":"10","article-title":"Helicobacter pylori infection in oral lesions of patients with recurrent aphthous stomatitis","volume":"11","author":"F. Mansour-Ghanaei","year":"2005","journal-title":"Medical Science Monitor"},{"key":"11","doi-asserted-by":"publisher","DOI":"10.1111\/j.0904-2512.2004.00074.x"},{"key":"12","doi-asserted-by":"publisher","DOI":"10.2334\/josnusd.45.107"},{"key":"13","doi-asserted-by":"publisher","DOI":"10.1111\/j.1601-0825.2004.01043.x"},{"key":"14","doi-asserted-by":"publisher","DOI":"10.1099\/0022-1317-49-4-349"},{"key":"15","doi-asserted-by":"publisher","DOI":"10.4103\/jpbs.JPBS_260_18"},{"key":"16","doi-asserted-by":"publisher","DOI":"10.3748\/wjg.v21.i40"}],"container-title":["Case Reports in Gastrointestinal Medicine"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/downloads.hindawi.com\/journals\/crigm\/2021\/5543838.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/downloads.hindawi.com\/journals\/crigm\/2021\/5543838.xml","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/downloads.hindawi.com\/journals\/crigm\/2021\/5543838.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2021,3,30]],"date-time":"2021-03-30T18:56:30Z","timestamp":1617130590000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.hindawi.com\/journals\/crigm\/2021\/5543838\/"}},"subtitle":[],"editor":[{"given":"Ken","family":"Haruma","sequence":"additional","affiliation":[],"role":[{"role":"editor","vocabulary":"crossref"}]}],"short-title":[],"issued":{"date-parts":[[2021,3,30]]},"references-count":16,"alternative-id":["5543838","5543838"],"URL":"https:\/\/doi.org\/10.1155\/2021\/5543838","relation":{},"ISSN":["2090-6536","2090-6528"],"issn-type":[{"value":"2090-6536","type":"electronic"},{"value":"2090-6528","type":"print"}],"subject":[],"published":{"date-parts":[[2021,3,30]]}}}