{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,28]],"date-time":"2026-10-28T18:39:21Z","timestamp":1793212761632,"version":"4.5.0"},"reference-count":44,"publisher":"Wiley","license":[{"start":{"date-parts":[[2021,7,20]],"date-time":"2021-07-20T00:00:00Z","timestamp":1626739200000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100004484","name":"Tehran University of Medical Sciences","doi-asserted-by":"crossref","id":[{"id":"10.13039\/501100004484","id-type":"DOI","asserted-by":"crossref"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Evidence-Based Complementary and Alternative Medicine"],"published-print":{"date-parts":[[2021,7,20]]},"abstract":"<jats:p>\n                    Endometriosis is a common chronic inflammatory disease. Garlic contains components that have antiproliferative, anti-inflammatory, and antioxidative effects. The current study aimed to evaluate the effectiveness of garlic on endometriosis symptoms. This was a randomized placebo-controlled triple-blind clinical trial. A convenience sample of 60 women was randomly allocated into two groups. The intervention group received usual care supplemented with 400\u2009mg garlic tablets, and the placebo group received identical placebo tablets. A four-part Visual Analogue Scale (VAS) was used to measure the severity of pains. The pains were measured on four occasions (before the intervention and on one-, two-, and three-month follow-ups). Data were analyzed using the t-test, chi-square, repeated measures ANOVA, and ANCOVA by SPSS 16. The overall severity of pain reduced from 6.51\u2009\u00b1\u20090.86 to 1.83\u2009\u00b1\u20091.25 in the intervention group (\n                    <jats:inline-formula>\n                      <a:math xmlns:a=\"http:\/\/www.w3.org\/1998\/Math\/MathML\" id=\"M1\">\n                        <a:mi>p<\/a:mi>\n                      <\/a:math>\n                    <\/jats:inline-formula>\n                    \u2009&lt;\u20090.05). It increased from 6.41\u2009\u00b1\u20091.12 to 6.65\u2009\u00b1\u20091.37 in the control group (\n                    <jats:inline-formula>\n                      <c:math xmlns:c=\"http:\/\/www.w3.org\/1998\/Math\/MathML\" id=\"M2\">\n                        <c:mi>p<\/c:mi>\n                      <\/c:math>\n                    <\/jats:inline-formula>\n                    \u2009=\u20090.02). The repeated measures ANOVA showed that there is a significant difference in the change of pain scores between intervention and control groups (\n                    <jats:inline-formula>\n                      <e:math xmlns:e=\"http:\/\/www.w3.org\/1998\/Math\/MathML\" id=\"M3\">\n                        <e:mi>p<\/e:mi>\n                      <\/e:math>\n                    <\/jats:inline-formula>\n                    \u2009&lt;\u20090.001, np2\u2009=\u20090.572). Garlic extract can reduce pelvic and back pain, dysmenorrhea, and dyspareunia which are important symptoms of endometriosis.\n                  <\/jats:p>","DOI":"10.1155\/2021\/5547058","type":"journal-article","created":{"date-parts":[[2021,7,20]],"date-time":"2021-07-20T14:05:07Z","timestamp":1626789907000},"page":"1-8","source":"Crossref","is-referenced-by-count":30,"title":["The Effect of Garlic Tablets on the Endometriosis-Related Pains: A Randomized Placebo-Controlled Clinical Trial"],"prefix":"10.1155","volume":"2021","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-3744-6578","authenticated-orcid":true,"given":"Sudabeh","family":"Amirsalari","sequence":"first","affiliation":[{"name":"Department of Reproductive Health Midwifery, School of Nursing & Midwifery, Tehran University of Medical Sciences, Tehran, Iran"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4708-3590","authenticated-orcid":true,"given":"Zahra","family":"Behboodi Moghadam","sequence":"additional","affiliation":[{"name":"Department of Reproductive Health Midwifery, School of Nursing & Midwifery, Tehran University of Medical Sciences, Tehran, Iran"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ziba","family":"Taghizadeh","sequence":"additional","affiliation":[{"name":"Department of Reproductive Health Midwifery, School of Nursing & Midwifery, Tehran University of Medical Sciences, Tehran, Iran"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7634-4801","authenticated-orcid":true,"given":"Mina Naghi","family":"Jafar Abadi","sequence":"additional","affiliation":[{"name":"Vali-E-Asr Reproductive Health Research Center, Tehran University of Medical Sciences, Tehran, Iran"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3760-5524","authenticated-orcid":true,"given":"Parichehr","family":"Sabaghzadeh Irani","sequence":"additional","affiliation":[{"name":"Hormozgan University of Medical Sciences, Bandar Abbas, Iran"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3112-042X","authenticated-orcid":true,"given":"Saied","family":"Goodarzi","sequence":"additional","affiliation":[{"name":"Medicinal Plants Research Center, Faculty of Pharmacy, Tehran University of Medical Sciences, Tehran, Iran"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3672-7266","authenticated-orcid":true,"given":"Hadi","family":"Ranjbar","sequence":"additional","affiliation":[{"name":"Mental Health Research Center, Psychosocial Health Research Institute, Iran University of Medical Science, Tehran, Iran"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","reference":[{"key":"1","doi-asserted-by":"publisher","DOI":"10.3390\/ijerph17134683"},{"key":"2","doi-asserted-by":"publisher","DOI":"10.1007\/s12325-017-0619-3"},{"key":"3","doi-asserted-by":"publisher","DOI":"10.1111\/apt.13425"},{"key":"4","doi-asserted-by":"publisher","DOI":"10.1007\/s10815-014-0237-9"},{"key":"5","doi-asserted-by":"publisher","DOI":"10.7759\/cureus.9614"},{"issue":"11","key":"6","first-page":"21703","article-title":"Clinical analyses of endometriosis after conservative surgery","volume":"8","author":"X. 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