{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,15]],"date-time":"2026-01-15T22:14:58Z","timestamp":1768515298629,"version":"3.49.0"},"reference-count":67,"publisher":"Wiley","license":[{"start":{"date-parts":[[2021,4,26]],"date-time":"2021-04-26T00:00:00Z","timestamp":1619395200000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100001780","name":"RMIT University","doi-asserted-by":"publisher","award":["GWV-10.1-XK20"],"award-info":[{"award-number":["GWV-10.1-XK20"]}],"id":[{"id":"10.13039\/501100001780","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001780","name":"RMIT University","doi-asserted-by":"publisher","award":["201940058"],"award-info":[{"award-number":["201940058"]}],"id":[{"id":"10.13039\/501100001780","id-type":"DOI","asserted-by":"publisher"}]},{"name":"Shanghai Sanda University","award":["GWV-10.1-XK20"],"award-info":[{"award-number":["GWV-10.1-XK20"]}]},{"name":"Shanghai Sanda University","award":["201940058"],"award-info":[{"award-number":["201940058"]}]},{"name":"Shanghai Municipal Health Commission","award":["GWV-10.1-XK20"],"award-info":[{"award-number":["GWV-10.1-XK20"]}]},{"name":"Shanghai Municipal Health Commission","award":["201940058"],"award-info":[{"award-number":["201940058"]}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Evidence-Based Complementary and Alternative Medicine"],"published-print":{"date-parts":[[2021,4,26]]},"abstract":"<jats:p>Background. Many women with perimenopausal insomnia (PMI) have sought alternative therapies such as acupuncture because of concerns about risks associated with hormone replacement therapy (HRT) and\/or psychotropic drugs. This systematic review aimed to clarify if acupuncture alone or combined with standard Western pharmacotherapy (HRT and\/or psychotropic drugs) is more effective in ameliorating PMI in comparison to pharmacotherapy alone. Methods. Randomized controlled trials (RCTs) of PMI treatment via acupuncture alone or combined with Western pharmacotherapy versus Western pharmacotherapy were searched for from eleven databases from inception to March 2020. Cochrane criteria were followed. Results. Fifteen studies involving 1410 women were analyzed. Meta-analysis indicated that acupuncture significantly reduced the global scores of Pittsburgh Sleep Quality Index (PSQI) [MD\u2009=\u2009\u22122.38, 95% CI (\u22123.38, \u22121.37), <jats:inline-formula>\n                     <a:math xmlns:a=\"http:\/\/www.w3.org\/1998\/Math\/MathML\" id=\"M1\">\n                        <a:mi>p<\/a:mi>\n                     <\/a:math>\n                  <\/jats:inline-formula>\u2009&lt;\u20090.01] and Kupperman Index [MD\u2009=\u2009\u22125.95, 95% CI (\u221210.68, \u22121.21), <jats:inline-formula>\n                     <c:math xmlns:c=\"http:\/\/www.w3.org\/1998\/Math\/MathML\" id=\"M2\">\n                        <c:mi>p<\/c:mi>\n                     <\/c:math>\n                  <\/jats:inline-formula>\u2009=\u20090.01], compared with hypnotics. Acupuncture combined with hypnotics was more effective than hypnotics alone in decreasing PSQI scores [MD\u2009=\u2009\u22123.13, 95% CI (\u22125.43, \u22120.83), <jats:inline-formula>\n                     <e:math xmlns:e=\"http:\/\/www.w3.org\/1998\/Math\/MathML\" id=\"M3\">\n                        <e:mi>p<\/e:mi>\n                     <\/e:math>\n                  <\/jats:inline-formula>\u2009&lt;\u20090.01]. Too few RCTs were available to investigate the clinical efficacy differences between acupuncture and HRT\/psychotropic drugs other than hypnotics. Conclusions. Despite limited evidence, in comparison to hypnotics, acupuncture was associated with significant improvements in PMI, and reductions of other menopausal symptoms. This finding suggests that acupuncture may be a useful addition to treatment for PMI.<\/jats:p>","DOI":"10.1155\/2021\/5566742","type":"journal-article","created":{"date-parts":[[2021,4,26]],"date-time":"2021-04-26T21:25:19Z","timestamp":1619472319000},"page":"1-16","source":"Crossref","is-referenced-by-count":16,"title":["Comparative Utility of Acupuncture and Western Medication in the Management of Perimenopausal Insomnia: A Systematic Review and Meta-Analysis"],"prefix":"10.1155","volume":"2021","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-9009-8870","authenticated-orcid":true,"given":"Fei-Yi","family":"Zhao","sequence":"first","affiliation":[{"name":"School of Health and Biomedical Sciences, RMIT University, Bundoora, Victoria 3083, Australia"},{"name":"Shanghai Municipal Hospital of Traditional Chinese Medicine, Shanghai University of Traditional Chinese Medicine, Shanghai 200071, China"},{"name":"Department of Nursing, School of International Medical Technology, Shanghai Sanda University, Shanghai 201209, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2369-1508","authenticated-orcid":true,"given":"Qiang-Qiang","family":"Fu","sequence":"additional","affiliation":[{"name":"Yangpu Hospital, Tongji University School of Medicine, Shanghai, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4419-050X","authenticated-orcid":true,"given":"Gerard A.","family":"Kennedy","sequence":"additional","affiliation":[{"name":"School of Science, Psychology and Sport, Federation University, Mount Helen, Victoria, Australia"},{"name":"School of Health and Biomedical Sciences, RMIT University, Bundoora, Victoria 3083, Australia"},{"name":"Institute for Breathing and Sleep, Austin Health, Heidelberg, Victoria 3084, Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9356-6844","authenticated-orcid":true,"given":"Russell","family":"Conduit","sequence":"additional","affiliation":[{"name":"School of Health and Biomedical Sciences, RMIT University, Bundoora, Victoria 3083, Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9227-5671","authenticated-orcid":true,"given":"Wen-Zhong","family":"Wu","sequence":"additional","affiliation":[{"name":"Jiangsu Province Hospital of Chinese Medicine, Affiliated Hospital of Nanjing University of Chinese Medicine, Nanjing, Jiangsu, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3716-6800","authenticated-orcid":true,"given":"Wen-Jing","family":"Zhang","sequence":"additional","affiliation":[{"name":"Shanghai Municipal Hospital of Traditional Chinese Medicine, Shanghai University of Traditional Chinese Medicine, Shanghai 200071, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6777-1166","authenticated-orcid":true,"given":"Zhen","family":"Zheng","sequence":"additional","affiliation":[{"name":"School of Health and Biomedical Sciences, RMIT University, Bundoora, Victoria 3083, Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","reference":[{"key":"1","doi-asserted-by":"publisher","DOI":"10.1097\/grf.0000000000000389"},{"key":"2","doi-asserted-by":"publisher","DOI":"10.3109\/13697130903353478"},{"key":"3","doi-asserted-by":"publisher","DOI":"10.1186\/s13063-017-2072-7"},{"key":"4","doi-asserted-by":"publisher","DOI":"10.12740\/PP\/33442"},{"key":"5","doi-asserted-by":"publisher","DOI":"10.1007\/s40675-017-0084-1"},{"key":"6","doi-asserted-by":"publisher","DOI":"10.1016\/j.jogn.2017.07.011"},{"issue":"2","key":"7","first-page":"e1","article-title":"Sleep in America poll: adult sleep habits","volume":"1","author":"National Sleep Foundation","year":"2002","journal-title":"Sleep Health"},{"key":"8","doi-asserted-by":"publisher","DOI":"10.1080\/0167482x.2016.1244181"},{"key":"9","doi-asserted-by":"publisher","DOI":"10.1016\/0378-5122(81)90014-1"},{"key":"10","doi-asserted-by":"publisher","DOI":"10.5665\/sleep.2448"},{"issue":"8","key":"11","first-page":"13","article-title":"Clinical and socioeconomic correlates of insomnia","volume":"65","author":"J. 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