{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,13]],"date-time":"2026-01-13T03:35:16Z","timestamp":1768275316745,"version":"3.49.0"},"reference-count":12,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2021,3,10]],"date-time":"2021-03-10T00:00:00Z","timestamp":1615334400000},"content-version":"vor","delay-in-days":68,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Case Reports in Endocrinology"],"published-print":{"date-parts":[[2021,1]]},"abstract":"<jats:p>\n                    <jats:italic>Objective<\/jats:italic>\n                    . This case highlights use of 1\u201034 PTH continuous infusion in a patient with postsurgical hypoparathyroidism.\n                    <jats:italic>Method<\/jats:italic>\n                    . Clinical presentation and biochemical profile were monitored before and after 1\u201034 PTH infusion, with notable reduction in pill burden in a patient with postsurgical hypoparathyroidism.\n                    <jats:italic>Results<\/jats:italic>\n                    . We present a case of postsurgical hypoparathyroidism following thyroidectomy for Graves disease. The patient was requiring a total of 34 pills daily and, despite medication compliance, her clinical and biochemical control was unsatisfactory. Following initiation of 1\u201034 PTH in the form of a subcutaneous pump, we were able to stop all calcium supplementation and reduce calcitriol to 0.5 mcg daily. Her current biochemical control as well as quality of life improved significantly on CSPI, calcitriol, and a daily serving of dietary calcium.\n                    <jats:italic>Conclusion<\/jats:italic>\n                    . This case highlights the use of 1\u201034 PTH either as twice\u2010daily dosing or continuous subcutaneous infusion for adult patients with hypoparathyroidism.\n                  <\/jats:p>","DOI":"10.1155\/2021\/5593653","type":"journal-article","created":{"date-parts":[[2021,3,10]],"date-time":"2021-03-10T11:50:08Z","timestamp":1615377008000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":3,"title":["Desperate Times Call for Desperate Measures: Use of Continuous Subcutaneous 1\u201034 PTH Infusion for Postsurgical Hypoparathyroidism"],"prefix":"10.1155","volume":"2021","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-2711-2497","authenticated-orcid":false,"given":"Adnan","family":"Haider","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Oksana","family":"Symczyk","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yadel","family":"Couso","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Taylor","family":"Cater","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sheree","family":"Bryan","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2021,3,10]]},"reference":[{"key":"e_1_2_6_1_2","doi-asserted-by":"publisher","DOI":"10.1074\/jbc.270.26.15455"},{"key":"e_1_2_6_2_2","unstructured":"CareA. D.andBellN. H. ConnD. V. MartinR. J. andMeunierJ. Evidence that parathyroid hormone crosses the blood-brain barrier Calcium Regulation and Bone Metabolism: Basic and Clinical Aspects Proceedings of the 9th International Conference on Calcium Regulating Hormones and Bone Metabolism November 1986 Nice France Elsevier New York NY USA."},{"key":"e_1_2_6_3_2","doi-asserted-by":"publisher","DOI":"10.1210\/jc.2015-3907"},{"key":"e_1_2_6_4_2","doi-asserted-by":"publisher","DOI":"10.1001\/jama.276.8.631"},{"key":"e_1_2_6_5_2","doi-asserted-by":"publisher","DOI":"10.1210\/jc.2015-1855"},{"key":"e_1_2_6_6_2","doi-asserted-by":"publisher","DOI":"10.1210\/jc.2017-01555"},{"key":"e_1_2_6_7_2","doi-asserted-by":"publisher","DOI":"10.1210\/jc.2011-1908"},{"key":"e_1_2_6_8_2","doi-asserted-by":"publisher","DOI":"10.1210\/jc.2011-1359"},{"key":"e_1_2_6_9_2","doi-asserted-by":"publisher","DOI":"10.1080\/01926230601072301"},{"key":"e_1_2_6_10_2","doi-asserted-by":"publisher","DOI":"10.1080\/01926230252929882"},{"key":"e_1_2_6_11_2","doi-asserted-by":"publisher","DOI":"10.1002\/jbmr.1800"},{"key":"e_1_2_6_12_2","doi-asserted-by":"publisher","DOI":"10.1002\/jbmr.1768"}],"container-title":["Case Reports in Endocrinology"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/downloads.hindawi.com\/journals\/crie\/2021\/5593653.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/downloads.hindawi.com\/journals\/crie\/2021\/5593653.xml","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1155\/2021\/5593653","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,11,7]],"date-time":"2025-11-07T00:05:30Z","timestamp":1762473930000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1155\/2021\/5593653"}},"subtitle":[],"editor":[{"given":"Micha\u00ef\u00bf\u00bdl R.","family":"Laurent","sequence":"additional","affiliation":[],"role":[{"role":"editor","vocabulary":"crossref"}]}],"short-title":[],"issued":{"date-parts":[[2021,1]]},"references-count":12,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2021,1]]}},"alternative-id":["10.1155\/2021\/5593653"],"URL":"https:\/\/doi.org\/10.1155\/2021\/5593653","archive":["Portico"],"relation":{},"ISSN":["2090-6501","2090-651X"],"issn-type":[{"value":"2090-6501","type":"print"},{"value":"2090-651X","type":"electronic"}],"subject":[],"published":{"date-parts":[[2021,1]]},"assertion":[{"value":"2021-01-17","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2021-03-02","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2021-03-10","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}],"article-number":"5593653"}}