{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,5,14]],"date-time":"2025-05-14T02:42:25Z","timestamp":1747190545787,"version":"3.40.5"},"reference-count":15,"publisher":"Wiley","license":[{"start":{"date-parts":[[2021,5,3]],"date-time":"2021-05-03T00:00:00Z","timestamp":1620000000000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Case Reports in Orthopedics"],"published-print":{"date-parts":[[2021,5,3]]},"abstract":"<jats:p>Introduction. Rotational displaced pelvic ring injuries are associated with internal injuries to both the gastrointestinal and genitourinary viscera and anatomic structures. Vaginal lacerations and open genitourinary-associated injuries are at increased risk of mortality due to sepsis. Case Presentation. This case presents a 65-year-old female status post-pedestrian-vehicle struck diagnosed with an open pelvic fracture with extension into the outer one-third of the vaginal wall. The patient was successfully treated with emergent surgical debridement, pelvic stabilization, and internal placement of a novel combination of metronidazole antibiotic gel and vancomycin\/tobramycin Polymethyl methacrylate beads. Conclusion. No evidence of infection was observed with the use of topical metronidazole-coated vancomycin\/tobramycin Polymethyl methacrylate beads for contaminated open pelvic fracture injury involving the vaginal wall. Further research on antibiotic gels for use in high-risk open fractures is required.<\/jats:p>","DOI":"10.1155\/2021\/5594270","type":"journal-article","created":{"date-parts":[[2021,5,4]],"date-time":"2021-05-04T22:50:06Z","timestamp":1620168606000},"page":"1-5","source":"Crossref","is-referenced-by-count":1,"title":["Vaginal Laceration in an Open Pelvic Fracture Case Report: A Novel, Prophylactic Antibiotic Delivery Mechanism"],"prefix":"10.1155","volume":"2021","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-1608-159X","authenticated-orcid":true,"given":"Nishant","family":"Suneja","sequence":"first","affiliation":[{"name":"Department of Orthopaedic Surgery, Harvard Medical School, Massachusetts General, 55 Fruit Street, Yawkey 3C, Boston, MA 02114, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2098-0440","authenticated-orcid":true,"given":"Eric H.","family":"Tischler","sequence":"additional","affiliation":[{"name":"Department of Orthopaedic Surgery and Rehabilitation Medicine, State University of New York, Downstate Medical Center, 450 Clarkson Avenue, MSC 30, Brooklyn, NY 11203, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Skye","family":"Lockwood","sequence":"additional","affiliation":[{"name":"University of Vermont, 184 S Prospect St., Burlington, VT 05401, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Adam J.","family":"Wolfert","sequence":"additional","affiliation":[{"name":"Department of Orthopaedic Surgery and Rehabilitation Medicine, State University of New York, Downstate Medical Center, 450 Clarkson Avenue, MSC 30, Brooklyn, NY 11203, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Daniel","family":"Martingano","sequence":"additional","affiliation":[{"name":"Department of Obstetrics & Gynecology, New York University Langone Hospital, 150 55th Brooklyn, NY 11220, USA"},{"name":"New York University School of Medicine, Department of Obstetrics & Gynecology, 150 55th, Brooklyn, NY 11220, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Piyapa","family":"Praditpan","sequence":"additional","affiliation":[{"name":"Department of Obstetrics & Gynecology, New York University Langone Hospital, 150 55th Brooklyn, NY 11220, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Thomas","family":"Lyon","sequence":"additional","affiliation":[{"name":"Department of Orthopedic Surgery, New York University Langone Hospital, 150 55th Street, Brooklyn, NY 11220, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","reference":[{"key":"1","doi-asserted-by":"publisher","DOI":"10.1097\/TA.0b013e3182827496"},{"key":"2","first-page":"193","article-title":"Open pelvic fractures: the University of Tennessee Medical Center at Knoxville experience over ten years","volume":"31","author":"E. 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