{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,8,6]],"date-time":"2025-08-06T12:18:08Z","timestamp":1754482688857,"version":"3.40.5"},"reference-count":22,"publisher":"Wiley","license":[{"start":{"date-parts":[[2021,4,1]],"date-time":"2021-04-01T00:00:00Z","timestamp":1617235200000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"name":"Lake Erie College of Osteopathic Medicine","award":["J2018.37"],"award-info":[{"award-number":["J2018.37"]}]},{"name":"Lake Erie Consortium for Osteopathic Medical Training","award":["J2018.37"],"award-info":[{"award-number":["J2018.37"]}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["International Journal of Endocrinology"],"published-print":{"date-parts":[[2021,4,1]]},"abstract":"<jats:p>Background. Post-thyroidectomy hypocalcemia is the most common complication after total thyroidectomy. Studies to examine the role of low vitamin D in increasing post-thyroidectomy hypocalcemia incidence have produced varying results. This study aimed to assess whether vitamin D deficiency increases the risk of post-thyroidectomy hypocalcemia. Methods. This retrospective study involved 244 patients who underwent total thyroidectomy between 2014 and 2019. Patients were divided into two groups based on pre-operative vitamin D levels. Group A and Group B had pre-operative vitamin D (25-hydroxyvitamin D) levels of \u226520\u2009ng\/ml and &lt;20\u2009ng\/ml (reference range for vitamin D is 30\u2013100\u2009ng\/dl). The effect of vitamin D, gender, body mass index (BMI), and ethnicity on post-operative calcium and PTH levels was analyzed. Results. Post-operative calcium levels for Group A were not statistically different compared to Group B (8.52\u2009\u00b1\u20090.64\u2009mg\/dl vs. 8.45\u2009\u00b1\u20090.58\u2009mg\/dl (mean\u2009\u00b1\u2009S.D.; <jats:inline-formula>\n                     <a:math xmlns:a=\"http:\/\/www.w3.org\/1998\/Math\/MathML\" id=\"M1\">\n                        <a:mi>p<\/a:mi>\n                     <\/a:math>\n                  <\/jats:inline-formula> value\u2009=\u20090.352). The average post-operative PTH of the two groups did not differ significantly (Group A: 32.4\u2009\u00b1\u200927.5\u2009pg\/ml; Group B: 34.4\u2009\u00b1\u200941.7\u2009pg\/ml; <jats:inline-formula>\n                     <c:math xmlns:c=\"http:\/\/www.w3.org\/1998\/Math\/MathML\" id=\"M2\">\n                        <c:mi>p<\/c:mi>\n                     <\/c:math>\n                  <\/jats:inline-formula> value\u2009=\u20090.761). Conclusion. Pre-operative vitamin D levels are not predictive of post-thyroidectomy hypocalcemia.<\/jats:p>","DOI":"10.1155\/2021\/5598319","type":"journal-article","created":{"date-parts":[[2021,4,2]],"date-time":"2021-04-02T18:50:07Z","timestamp":1617389407000},"page":"1-5","source":"Crossref","is-referenced-by-count":5,"title":["Advancing the Understanding of Vitamin D Status in Post-Thyroidectomy Hypocalcemia"],"prefix":"10.1155","volume":"2021","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-6044-7419","authenticated-orcid":true,"given":"Gurdeep","family":"Singh","sequence":"first","affiliation":[{"name":"Our Lady of Lourdes Memorial Hospital, 161 Riverside Drive, Binghamton 13905, NY, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6616-9755","authenticated-orcid":true,"given":"Fatima","family":"Irshaidat","sequence":"additional","affiliation":[{"name":"Our Lady of Lourdes Memorial Hospital, 161 Riverside Drive, Binghamton 13905, NY, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3774-8309","authenticated-orcid":true,"given":"Christopher","family":"Lau","sequence":"additional","affiliation":[{"name":"Our Lady of Lourdes Memorial Hospital, 161 Riverside Drive, Binghamton 13905, NY, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ariel","family":"Pedoeem","sequence":"additional","affiliation":[{"name":"Our Lady of Lourdes Memorial Hospital, 161 Riverside Drive, Binghamton 13905, NY, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7259-6400","authenticated-orcid":true,"given":"Christine","family":"Feng","sequence":"additional","affiliation":[{"name":"Our Lady of Lourdes Memorial Hospital, 161 Riverside Drive, Binghamton 13905, NY, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4734-5722","authenticated-orcid":true,"given":"Maria Mohammed","family":"Fariduddin","sequence":"additional","affiliation":[{"name":"Upstate University Hospital, 3229 East Genesee Street, Syracuse 13214, NY, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1144-9423","authenticated-orcid":true,"given":"Lei Lei","family":"Min","sequence":"additional","affiliation":[{"name":"Upstate University Hospital, 3229 East Genesee Street, Syracuse 13214, NY, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7072-1311","authenticated-orcid":true,"given":"Nidhi","family":"Bansal","sequence":"additional","affiliation":[{"name":"Upstate University Hospital, 3229 East Genesee Street, Syracuse 13214, NY, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","reference":[{"doi-asserted-by":"publisher","key":"1","DOI":"10.1007\/s13304-017-0475-3"},{"doi-asserted-by":"publisher","key":"2","DOI":"10.4103\/abr.abr_3_19"},{"doi-asserted-by":"publisher","key":"3","DOI":"10.1007\/s00423-019-01748-3"},{"doi-asserted-by":"publisher","key":"4","DOI":"10.1097\/med.0000000000000359"},{"doi-asserted-by":"publisher","key":"5","DOI":"10.1007\/s11154-017-9424-1"},{"doi-asserted-by":"publisher","key":"6","DOI":"10.1038\/nrendo.2016.110"},{"doi-asserted-by":"publisher","key":"7","DOI":"10.1016\/j.surg.2019.01.007"},{"doi-asserted-by":"publisher","key":"8","DOI":"10.1016\/j.jss.2013.04.036"},{"doi-asserted-by":"publisher","key":"9","DOI":"10.1089\/thy.2012.0218"},{"doi-asserted-by":"publisher","key":"10","DOI":"10.1002\/bjs.9384"},{"doi-asserted-by":"publisher","key":"11","DOI":"10.1089\/thy.2017.0309"},{"doi-asserted-by":"publisher","key":"12","DOI":"10.1001\/jamaoto.2014.25"},{"doi-asserted-by":"publisher","key":"13","DOI":"10.1016\/j.surg.2015.08.014"},{"doi-asserted-by":"publisher","key":"14","DOI":"10.18632\/oncotarget.17690"},{"doi-asserted-by":"publisher","key":"15","DOI":"10.1016\/j.amjsurg.2013.08.020"},{"issue":"2","key":"16","first-page":"72","article-title":"Influence of thyroidectomy on postoperative serum calcium level regarding serum vitamin D status. A prospective study","volume":"6","author":"G. 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