{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,2]],"date-time":"2026-09-02T03:29:49Z","timestamp":1788319789658,"version":"build-2803163510"},"reference-count":33,"publisher":"Wiley","license":[{"start":{"date-parts":[[2021,8,12]],"date-time":"2021-08-12T00:00:00Z","timestamp":1628726400000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"name":"Tangshan Science and Technology Innovation Team Project","award":["18130220A"],"award-info":[{"award-number":["18130220A"]}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Evidence-Based Complementary and Alternative Medicine"],"published-print":{"date-parts":[[2021,8,12]]},"abstract":"<jats:p>Purpose. Transcutaneous electrical acupoint stimulation (TEAS) is widely used. However, no study evaluated TEAS on systemic inflammatory response syndrome (SIRS) of patients after percutaneous nephrolithotomy (PCNL). The study was to evaluate TEAS on SIRS of patients after PCNL. Methods. 67 patients were enrolled and divided into group TEAS and group sham TEAS. Data were collected from 60 participants finally. In the study, TEAS or sham TEAS on bilateral Shenshu (BL23), Yinlingquan (SP9), Hegu (LI4), and Neiguan (PC6) was performed continuously throughout the procedure. The primary outcome included the incidence of systemic inflammatory response syndrome (SIRS) within 48\u2009h after surgery. The secondary outcomes included the serum levels of inflammatory cytokines, hemodynamics changes, complications, and hospital stay after surgery. The serum levels of tumor necrosis factor- (TNF-) \u03b1 and interleukin- (IL-) 6, mean arterial pressure (MAP), and heart rate (HR) at 30\u2009min before anesthesia (T0), the time after surgery (T1), 24\u2009h postoperation (T2), and 48\u2009h postoperation (T3) were recorded. The consumption of analgesic during surgery was also recorded, as well as the complications and duration of hospital stay after PCNL. Results. The incidence of SIRS in group TEAS was lower than group sham TEAS (30% vs. 6.67%, <jats:inline-formula>\n                     <a:math xmlns:a=\"http:\/\/www.w3.org\/1998\/Math\/MathML\" id=\"M1\">\n                        <a:mi>p<\/a:mi>\n                        <a:mo>=<\/a:mo>\n                        <a:mn>0.023<\/a:mn>\n                     <\/a:math>\n                  <\/jats:inline-formula>). Compared with the sham TEAS group, both levels of TNF-\u03b1 and IL-6 at T1, T2, and T3 were lower in the TEAS group (<jats:inline-formula>\n                     <c:math xmlns:c=\"http:\/\/www.w3.org\/1998\/Math\/MathML\" id=\"M2\">\n                        <c:mi>p<\/c:mi>\n                        <c:mo>&lt;<\/c:mo>\n                        <c:mn>0.05<\/c:mn>\n                     <\/c:math>\n                  <\/jats:inline-formula>). The levels of MAP and HR in sham TEAS at T1, T2, and T3 were markedly higher than that in the TEAS group (<jats:inline-formula>\n                     <e:math xmlns:e=\"http:\/\/www.w3.org\/1998\/Math\/MathML\" id=\"M3\">\n                        <e:mi>p<\/e:mi>\n                        <e:mo>&lt;<\/e:mo>\n                        <e:mn>0.05<\/e:mn>\n                     <\/e:math>\n                  <\/jats:inline-formula>). The total consumption of propofol and remifentanil during surgery in group TEAS was lower than that in the sham TEAS group. The incidence of hypotension, hypertension, emergence agitation, and postoperative nausea and vomiting (PONV) was also lower in group TEAS after PCNL (<jats:inline-formula>\n                     <g:math xmlns:g=\"http:\/\/www.w3.org\/1998\/Math\/MathML\" id=\"M4\">\n                        <g:mi>p<\/g:mi>\n                        <g:mo>&lt;<\/g:mo>\n                        <g:mn>0.05<\/g:mn>\n                     <\/g:math>\n                  <\/jats:inline-formula>). Conclusions. TEAS could effectively reduce the incidence of SIRS and inflammatory cytokines for patients who underwent PCNL. In addition, TEAS helped to maintain the hemodynamic stability and cut down the consumption of analgesics during PCNL, reducing the complications after PCNL.<\/jats:p>","DOI":"10.1155\/2021\/5909956","type":"journal-article","created":{"date-parts":[[2021,8,12]],"date-time":"2021-08-12T18:05:08Z","timestamp":1628791508000},"page":"1-9","source":"Crossref","is-referenced-by-count":12,"title":["Effects of Transcutaneous Electrical Acupoint Stimulation on Systemic Inflammatory Response Syndrome of Patients after Percutaneous Nephrolithotomy: A Randomized Controlled Trial"],"prefix":"10.1155","volume":"2021","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-5577-8010","authenticated-orcid":true,"given":"Bin","family":"Que","sequence":"first","affiliation":[{"name":"Department of Anesthesiology, Hangzhou TCM Hospital Affiliated to Zhejiang Chinese Medical University, Hangzhou 310000, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8399-827X","authenticated-orcid":true,"given":"Qing","family":"Tu","sequence":"additional","affiliation":[{"name":"Department of Anesthesiology, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai 200000, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1541-4842","authenticated-orcid":true,"given":"Jinlin","family":"Shi","sequence":"additional","affiliation":[{"name":"Department of Anesthesiology, Tangshan People\u2019s Hospital, North China University of Science and Technology, Tangshan, Hebei 063000, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2595-5001","authenticated-orcid":true,"given":"Zhengzuo","family":"Wan","sequence":"additional","affiliation":[{"name":"Department of Anesthesiology, Hangzhou TCM Hospital Affiliated to Zhejiang Chinese Medical University, Hangzhou 310000, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3608-0113","authenticated-orcid":true,"given":"Yanan","family":"Li","sequence":"additional","affiliation":[{"name":"Department of Anesthesiology, Hangzhou TCM Hospital Affiliated to Zhejiang Chinese Medical University, Hangzhou 310000, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8173-947X","authenticated-orcid":true,"given":"Rong","family":"Zhou","sequence":"additional","affiliation":[{"name":"Department of Anesthesiology, Hangzhou TCM Hospital Affiliated to Zhejiang Chinese Medical University, Hangzhou 310000, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0122-1932","authenticated-orcid":true,"given":"Hong","family":"Yu","sequence":"additional","affiliation":[{"name":"Department of Anesthesiology, Tangshan People\u2019s Hospital, North China University of Science and Technology, Tangshan, Hebei 063000, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4946-3554","authenticated-orcid":true,"given":"Jianhui","family":"Gan","sequence":"additional","affiliation":[{"name":"Department of Anesthesiology, Tangshan People\u2019s Hospital, North China University of Science and Technology, Tangshan, Hebei 063000, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1113-7881","authenticated-orcid":true,"given":"Jianming","family":"Yu","sequence":"additional","affiliation":[{"name":"Department of Anesthesiology, Hangzhou TCM Hospital Affiliated to Zhejiang Chinese Medical University, Hangzhou 310000, China"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","reference":[{"key":"1","doi-asserted-by":"publisher","DOI":"10.1007\/s00345-017-2001-0"},{"key":"2","doi-asserted-by":"publisher","DOI":"10.1089\/end.2007.0092"},{"key":"3","doi-asserted-by":"publisher","DOI":"10.1016\/j.eururo.2006.10.020"},{"key":"4","doi-asserted-by":"publisher","DOI":"10.1378\/chest.101.6.1644"},{"key":"5","first-page":"269","article-title":"Multiple functions of transcutaneous electrical acupoint stimulation in perianesthesia period","volume":"35","author":"J. L. Gao","year":"2015","journal-title":"Chinese Acupuncture & Moxibustion"},{"key":"6","doi-asserted-by":"publisher","DOI":"10.1093\/bja\/aeu001"},{"key":"7","doi-asserted-by":"publisher","DOI":"10.1093\/ecam\/neq015"},{"key":"8","doi-asserted-by":"publisher","DOI":"10.1080\/0962935031000114943"},{"key":"9","doi-asserted-by":"publisher","DOI":"10.1186\/s13052-015-0155-1"},{"key":"10","doi-asserted-by":"publisher","DOI":"10.1631\/jzus.b1600437"},{"key":"11","doi-asserted-by":"publisher","DOI":"10.1056\/nejmoa1415236"},{"key":"12","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijsu.2019.10.036"},{"key":"13","doi-asserted-by":"publisher","DOI":"10.1016\/j.juro.2016.01.104"},{"key":"14","doi-asserted-by":"publisher","DOI":"10.1186\/s40064-016-2830-0"},{"key":"15","first-page":"23","article-title":"The effect of transcutaneous electrical nerve stimulation on sympathetic skin response","volume":"44","author":"G. R. Olyaei","year":"2004","journal-title":"Electromyography & Clinical Neurophysiology"},{"key":"16","doi-asserted-by":"publisher","DOI":"10.1155\/2017\/8369737"},{"key":"17","doi-asserted-by":"publisher","DOI":"10.1136\/acupmed-2014-010752"},{"key":"18","doi-asserted-by":"publisher","DOI":"10.4037\/ajcc2011142"},{"key":"19","doi-asserted-by":"publisher","DOI":"10.1142\/s0192415x0500276x"},{"key":"20","doi-asserted-by":"publisher","DOI":"10.1016\/j.jams.2014.10.009"},{"key":"21","first-page":"179","article-title":"Eeperience of treating 30 cases of biliary and renal colic by acuponcture of SP9","volume":"24","author":"S. H. Luo","year":"2009","journal-title":"Journal of Traditional Chinese Medicine"},{"key":"22","doi-asserted-by":"publisher","DOI":"10.1007\/s00240-018-1056-8"},{"key":"23","doi-asserted-by":"publisher","DOI":"10.1142\/s0192415x11008786"},{"key":"24","doi-asserted-by":"publisher","DOI":"10.1155\/2013\/419212"},{"key":"25","doi-asserted-by":"publisher","DOI":"10.1097\/00003246-200210000-00024"},{"key":"26","doi-asserted-by":"publisher","DOI":"10.1523\/jneurosci.3338-07.2008"},{"key":"27","doi-asserted-by":"publisher","DOI":"10.1016\/j.neuron.2020.07.015"},{"key":"28","doi-asserted-by":"publisher","DOI":"10.3349\/ymj.2011.52.6.1016"},{"key":"29","doi-asserted-by":"publisher","DOI":"10.1213\/ane.0b013e318246536d"},{"key":"30","doi-asserted-by":"publisher","DOI":"10.1016\/j.jpain.2008.12.012"},{"key":"31","doi-asserted-by":"publisher","DOI":"10.1186\/1744-8069-7-98"},{"key":"32","doi-asserted-by":"publisher","DOI":"10.1097\/00029330-200703010-00009"},{"key":"33","doi-asserted-by":"publisher","DOI":"10.1007\/s00540-011-1198-0"}],"container-title":["Evidence-Based Complementary and Alternative Medicine"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/downloads.hindawi.com\/journals\/ecam\/2021\/5909956.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/downloads.hindawi.com\/journals\/ecam\/2021\/5909956.xml","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/downloads.hindawi.com\/journals\/ecam\/2021\/5909956.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2021,8,12]],"date-time":"2021-08-12T18:05:17Z","timestamp":1628791517000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.hindawi.com\/journals\/ecam\/2021\/5909956\/"}},"subtitle":[],"editor":[{"given":"Jiangyong","family":"Gu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"editor"}]}],"short-title":[],"issued":{"date-parts":[[2021,8,12]]},"references-count":33,"alternative-id":["5909956","5909956"],"URL":"https:\/\/doi.org\/10.1155\/2021\/5909956","relation":{},"ISSN":["1741-4288","1741-427X"],"issn-type":[{"value":"1741-4288","type":"electronic"},{"value":"1741-427X","type":"print"}],"subject":[],"published":{"date-parts":[[2021,8,12]]}}}