{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,27]],"date-time":"2026-03-27T15:12:49Z","timestamp":1774624369490,"version":"3.50.1"},"reference-count":35,"publisher":"Wiley","license":[{"start":{"date-parts":[[2021,11,28]],"date-time":"2021-11-28T00:00:00Z","timestamp":1638057600000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Journal of Tropical Medicine"],"published-print":{"date-parts":[[2021,11,28]]},"abstract":"<jats:p>Schistosoma mansoni infection is common among school-age children (SAC) in western C\u00f4te d\u2019Ivoire. Little is known on the infection rate of preschool-aged children (PSAC) due to epidemiological data deficiency and nonappropriate formulation of the drug. Thus, mass drug administration for schistosomiasis control mainly targets SAC. This study aims to identify the risk factors and spatial distribution of S. mansoni infection among PSAC in Blapleu, endemic foci of S. mansoni. We carried out a cross-sectional study in households with PSAC aged 1\u20136 years. A structured questionnaire was administered to mothers\/guardians to obtain data on sociodemographics and water contact behaviour of children. Point-of-care circulating cathodic antigen (POC-CCA) immunodiagnostic test in urine and Kato-Katz (K-K) method with stool were used for S. mansoni infection diagnosis. Multiple logistic regression analysis was performed to determine the relationship between S. mansoni infection and sociodemographic data. Coordinates recorded by a Global Positioning System of households, water source points, and infected PSAC were used to map the spatial distribution of S. mansoni infection cases. This study was conducted with 350 PSAC aged 1\u20136 years. The overall infection prevalence of S. mansoni varies from 31.43% with the K-K method to 62.86% with the POC-CCA. PSAC aged 2\u20136 years were highly infected with S. mansoni than those aged 1-2 years (OR\u2009=\u200914.24, 95% CI: 5.85\u201334.64). PSAC who did not have access and who do not live close to the infected water source were at a significant lower risk of S. mansoni infection (OR\u2009=\u20090.13, 95% CI: 0.057\u20130.30). The main purpose of water contact of PSAC was to help their mother for laundry that occurs weekly. In Blapleu, a high risk of S. mansoni infection was observed among PSAC. Schistosomiasis control effort in such localities should include information, education, and communication, water, sanitation, and hygiene, and particularly chemotherapy targeting PSAC, reinforcing the need of the paediatric praziquantel formulation.<\/jats:p>","DOI":"10.1155\/2021\/6224401","type":"journal-article","created":{"date-parts":[[2021,11,28]],"date-time":"2021-11-28T21:05:06Z","timestamp":1638133506000},"page":"1-8","source":"Crossref","is-referenced-by-count":5,"title":["Risk Factors and Spatial Distribution of Schistosoma mansoni Infection among Preschool-Aged Children in Blapleu, Biankouma District, Western C\u00f4te d\u2019Ivoire"],"prefix":"10.1155","volume":"2021","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-3218-2913","authenticated-orcid":true,"given":"Constant Konan","family":"N\u2019Zi","sequence":"first","affiliation":[{"name":"Institut National de Sant\u00e9 Publique, Abidjan BP V 46, C\u00f4te d\u2019Ivoire"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mamadou","family":"Ouattara","sequence":"additional","affiliation":[{"name":"Universit\u00e9 F\u00e9lix Houphou\u00ebt-Boigny, 22 BP 582, Abidjan 22, C\u00f4te d\u2019Ivoire"},{"name":"Centre Suisse de Recherches Scientifiques en C\u00f4te D\u2019Ivoire, 01 BP 1303, Abidjan, C\u00f4te d\u2019Ivoire"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Rufin Kouassi","family":"Assar\u00e9","sequence":"additional","affiliation":[{"name":"Universit\u00e9 F\u00e9lix Houphou\u00ebt-Boigny, 22 BP 582, Abidjan 22, C\u00f4te d\u2019Ivoire"},{"name":"Centre Suisse de Recherches Scientifiques en C\u00f4te D\u2019Ivoire, 01 BP 1303, Abidjan, C\u00f4te d\u2019Ivoire"},{"name":"Swiss Tropical and Public Health Institute, CH-4002, Basel, Switzerland"},{"name":"University of Basel, CH-4003, Basel, Switzerland"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Fid\u00e8le Kouakou","family":"Bassa","sequence":"additional","affiliation":[{"name":"Universit\u00e9 F\u00e9lix Houphou\u00ebt-Boigny, 22 BP 582, Abidjan 22, C\u00f4te d\u2019Ivoire"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Nana Rose","family":"Diakit\u00e9","sequence":"additional","affiliation":[{"name":"Universit\u00e9 F\u00e9lix Houphou\u00ebt-Boigny, 22 BP 582, Abidjan 22, C\u00f4te d\u2019Ivoire"},{"name":"Centre Suisse de Recherches Scientifiques en C\u00f4te D\u2019Ivoire, 01 BP 1303, Abidjan, C\u00f4te d\u2019Ivoire"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Eli\u00e9zer Kouakou","family":"N\u2019Goran","sequence":"additional","affiliation":[{"name":"Universit\u00e9 F\u00e9lix Houphou\u00ebt-Boigny, 22 BP 582, Abidjan 22, C\u00f4te d\u2019Ivoire"},{"name":"Centre Suisse de Recherches Scientifiques en C\u00f4te D\u2019Ivoire, 01 BP 1303, Abidjan, C\u00f4te d\u2019Ivoire"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","reference":[{"key":"1","volume-title":"Schistosomiasis","author":"WHO","year":"2020"},{"key":"2","first-page":"359","article-title":"\u201ccontrol of schistosomiasis and soil transmitted helminthiasis in sub-saharan africa: challenges and prospects","volume-title":"Current Topics in Tropical Medicine","author":"L. 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