{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,4]],"date-time":"2026-08-04T08:12:24Z","timestamp":1785831144118,"version":"3.56.0"},"reference-count":9,"publisher":"Wiley","license":[{"start":{"date-parts":[[2021,3,10]],"date-time":"2021-03-10T00:00:00Z","timestamp":1615334400000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Case Reports in Medicine"],"published-print":{"date-parts":[[2021,3,10]]},"abstract":"<jats:p>Oral bisphosphonates are approved for the treatment of bone loss associated with several conditions including postmenopausal osteoporosis. Although generally well tolerated, adverse effects such as gastroesophageal reflux and oesophageal and peptic ulceration may occur. Oral mucositis and ulceration are lesser-known side effects. Proper counselling and rigorous adherence to the administration instructions are crucial. We describe a case of bisphosphonate-induced severe oral mucosal ulceration in an elderly woman that was caused by incorrect instructions and\/or incorrect understanding of instructions for oral alendronate intake.<\/jats:p>","DOI":"10.1155\/2021\/6620489","type":"journal-article","created":{"date-parts":[[2021,3,10]],"date-time":"2021-03-10T22:35:10Z","timestamp":1615415710000},"page":"1-4","source":"Crossref","is-referenced-by-count":8,"title":["Severe Oral Mucosal Ulceration Associated with Oral Bisphosphonate Use: The Importance of Imparting Proper Instructions on Medication Administration and Intake"],"prefix":"10.1155","volume":"2021","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-9119-8443","authenticated-orcid":true,"given":"Manju","family":"Chandran","sequence":"first","affiliation":[{"name":"Complicated Metabolic Bone Disorders Clinic, Osteoporosis and Bone Metabolism Unit, Department of Endocrinology, Singapore General Hospital, Bukit Merah, Singapore"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Wanling","family":"Zeng","sequence":"additional","affiliation":[{"name":"Department of Endocrinology, Singapore General Hospital, Bukit Merah, Singapore"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","reference":[{"key":"1","doi-asserted-by":"publisher","DOI":"10.1177\/2040622310374783"},{"key":"2"},{"key":"3","doi-asserted-by":"publisher","DOI":"10.1155\/2014\/471035"},{"key":"4","doi-asserted-by":"publisher","DOI":"10.1034\/j.1600-0714.2000.291006.x"},{"key":"5","article-title":"Oral erosive mucositis associated with improper administration of a drug","volume":"76","author":"S. Ng","year":"2010","journal-title":"Journal (Canadian Dental Association)"},{"key":"6","doi-asserted-by":"publisher","DOI":"10.1016\/j.jaad.2003.07.030"},{"key":"7","doi-asserted-by":"publisher","DOI":"10.1016\/s1348-8643(12)00045-6"},{"key":"8","doi-asserted-by":"publisher","DOI":"10.1016\/j.jdsr.2013.12.001"},{"key":"9","first-page":"243","article-title":"Sign of Nikolsky and related signs","volume":"69","author":"D. Sachdev","year":"2003","journal-title":"Indian Journal of Dermatology, Venereology and Leprology"}],"container-title":["Case Reports in Medicine"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/downloads.hindawi.com\/journals\/crim\/2021\/6620489.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/downloads.hindawi.com\/journals\/crim\/2021\/6620489.xml","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/downloads.hindawi.com\/journals\/crim\/2021\/6620489.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2021,3,10]],"date-time":"2021-03-10T22:35:12Z","timestamp":1615415712000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.hindawi.com\/journals\/crim\/2021\/6620489\/"}},"subtitle":[],"editor":[{"given":"Aristomenis K.","family":"Exadaktylos","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"editor"}]}],"short-title":[],"issued":{"date-parts":[[2021,3,10]]},"references-count":9,"alternative-id":["6620489","6620489"],"URL":"https:\/\/doi.org\/10.1155\/2021\/6620489","relation":{},"ISSN":["1687-9635","1687-9627"],"issn-type":[{"value":"1687-9635","type":"electronic"},{"value":"1687-9627","type":"print"}],"subject":[],"published":{"date-parts":[[2021,3,10]]}}}