{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,2,21]],"date-time":"2025-02-21T22:32:05Z","timestamp":1740177125120,"version":"3.37.3"},"reference-count":23,"publisher":"Wiley","license":[{"start":{"date-parts":[[2021,3,20]],"date-time":"2021-03-20T00:00:00Z","timestamp":1616198400000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100003725","name":"National Research Foundation of Korea","doi-asserted-by":"publisher","award":["2019M3E5D1A02068106"],"award-info":[{"award-number":["2019M3E5D1A02068106"]}],"id":[{"id":"10.13039\/501100003725","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Pain Research and Management"],"published-print":{"date-parts":[[2021,3,20]]},"abstract":"<jats:p>Objective. Many patients with postpolio syndrome (PPS) experience pain. In this study, we aimed to review previous studies to investigate the effectiveness of intravenous immunoglobulin (IVIG) for managing pain in patients with PPS. We performed a narrative review. Methods. In PubMed, we searched for the keywords ((Immunoglobulin OR IVIG) AND (poliomyelitis OR poliomyelitis syndrome)). We included articles in which IVIG was infused in patients with PPS and pain severity was measured before and after treatment. Results. In the results, five articles (4 randomized controlled trials and 1 prospective observational study) were included in this review. Four of the studies reported that IVIG had a positive pain-reducing effect in patients with PPS. In addition, 4 studies evaluated the outcomes related to muscle strength and function. Of these studies, 3 showed some improvement in measurements for muscle strength and function. Conclusion. In conclusion, IVIG might be one of the beneficial options for managing pain in PPS. Pain reduction might be responsible for the improvement of muscle strength or function. To confirm the benefits of IVIG in reducing pain, more high-quality studies are required.<\/jats:p>","DOI":"10.1155\/2021\/6637705","type":"journal-article","created":{"date-parts":[[2021,3,22]],"date-time":"2021-03-22T19:35:05Z","timestamp":1616441705000},"page":"1-4","source":"Crossref","is-referenced-by-count":1,"title":["Effectiveness of Intravenous Immunoglobulin for Management of Pain in Patients with Postpolio Syndrome"],"prefix":"10.1155","volume":"2021","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-7629-7213","authenticated-orcid":true,"given":"Min Cheol","family":"Chang","sequence":"first","affiliation":[{"name":"Department of Rehabilitation Medicine, College of Medicine, Yeungnam University, Daegu, Republic of Korea"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5506-9206","authenticated-orcid":true,"given":"Jin-Sung","family":"Park","sequence":"additional","affiliation":[{"name":"Department of Neurology, School of Medicine, Kyungpook National University, Kyungpook National University Chilgok Hospital, Daegu, Republic of Korea"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9807-8783","authenticated-orcid":true,"given":"Jong-moon","family":"Hwang","sequence":"additional","affiliation":[{"name":"Department of Rehabilitation Medicine, School of Medicine, Kyungpook National University, Daegu, Republic of Korea"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7724-4682","authenticated-orcid":true,"given":"Donghwi","family":"Park","sequence":"additional","affiliation":[{"name":"Department of Physical Medicine and Rehabilitation, Ulsan University Hospital, University of Ulsan College of Medicine, Ulsan, Republic of Korea"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","reference":[{"issue":"7","key":"1","doi-asserted-by":"crossref","first-page":"845","DOI":"10.3928\/0147-7447-19850701-06","article-title":"New problems in old polio patients: results of a survey of 539 polio survivors","volume":"8","author":"L. 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