{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,16]],"date-time":"2026-02-16T02:57:55Z","timestamp":1771210675389,"version":"3.50.1"},"reference-count":28,"publisher":"Wiley","license":[{"start":{"date-parts":[[2021,4,6]],"date-time":"2021-04-06T00:00:00Z","timestamp":1617667200000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"name":"Veterans Administration Career Development Award","award":["IK1 BX007080"],"award-info":[{"award-number":["IK1 BX007080"]}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Computational and Mathematical Methods in Medicine"],"published-print":{"date-parts":[[2021,4,6]]},"abstract":"<jats:p>Mild, blast-induced traumatic brain injury (mbTBI) is a common combat brain injury characterized by typically normal neuroimaging findings, with unpredictable future cognitive recovery. Traditional methods of electroencephalography (EEG) analysis (e.g., spectral analysis) have not been successful in detecting the degree of cognitive and functional impairment in mbTBI. We therefore collected resting state EEG (5 minutes, 64 leads) from twelve patients with a history of mbTBI, along with repeat neuropsychological testing (D-KEFS Tower test) to compare two new methods for analyzing EEG (multifractal detrended fluctuation analysis (MF-DFA) and information transfer modeling (ITM)) with spectral analysis. For MF-DFA, we extracted relevant parameters from the resultant multifractal spectrum from all leads and compared with traditional power by frequency band for spectral analysis. For ITM, because the number of parameters from each lead far exceeded the number of subjects, we utilized a reduced set of 10 leads which were compared with spectral analysis. We utilized separate 30 second EEG segments for training and testing statistical models based upon regression tree analysis. ITM and MF-DFA models both generally had improved accuracy at correlating with relevant measures of cognitive performance as compared to spectral analytic models ITM and MF-DFA both merit additional research as analytic tools for EEG and cognition in TBI.<\/jats:p>","DOI":"10.1155\/2021\/6638724","type":"journal-article","created":{"date-parts":[[2021,4,7]],"date-time":"2021-04-07T22:23:43Z","timestamp":1617834223000},"page":"1-8","source":"Crossref","is-referenced-by-count":4,"title":["Information Transfer and Multifractal Analysis of EEG in Mild Blast-Induced TBI"],"prefix":"10.1155","volume":"2021","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-5851-785X","authenticated-orcid":true,"given":"Todd","family":"Zorick","sequence":"first","affiliation":[{"name":"Department of Psychiatry, Harbor-UCLA Medical Center and UCLA Geffen School of Medicine, USA"}]},{"given":"Katy D.","family":"Gaines","sequence":"additional","affiliation":[{"name":"Neuro Health Inc, University of California, Irvine, USA"}]},{"given":"Gholam R.","family":"Berenji","sequence":"additional","affiliation":[{"name":"Greater Los Angeles VA Department of Nuclear Imaging, University of California, Irvine, USA"}]},{"given":"Mark A.","family":"Mandelkern","sequence":"additional","affiliation":[{"name":"Greater Los Angeles VA Department of Nuclear Imaging, University of California, Irvine, USA"},{"name":"Department of Physics, University of California, Irvine, USA"}]},{"given":"Jason","family":"Smith","sequence":"additional","affiliation":[{"name":"The Boeing Company, USA"}]}],"member":"311","reference":[{"key":"1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pcbi.1000314"},{"key":"2","doi-asserted-by":"publisher","DOI":"10.3389\/fphys.2010.00015"},{"key":"3","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.1007841107"},{"key":"4","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0068360"},{"key":"5","doi-asserted-by":"publisher","DOI":"10.1016\/j.jocn.2020.04.003"},{"key":"6","doi-asserted-by":"publisher","DOI":"10.1155\/2016\/6450126"},{"key":"7","doi-asserted-by":"publisher","DOI":"10.4006\/1.3601352"},{"key":"8","article-title":"A general concept of natural information equilibrium from the ideal gas law to the K-Trumpler effect","author":"P. 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