{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,10]],"date-time":"2026-07-10T03:23:32Z","timestamp":1783653812298,"version":"3.55.0"},"reference-count":24,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2021,2,10]],"date-time":"2021-02-10T00:00:00Z","timestamp":1612915200000},"content-version":"vor","delay-in-days":40,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2021,1,1]],"date-time":"2021-01-01T00:00:00Z","timestamp":1609459200000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"funder":[{"name":"Hebei Province Medical Applicable Technology Tracking Project","award":["G2015062"],"award-info":[{"award-number":["G2015062"]}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Journal of Ophthalmology"],"published-print":{"date-parts":[[2021,1]]},"abstract":"<jats:p>\n                    <jats:italic>Purpose<\/jats:italic>\n                    . To compare the effectiveness and safety of carbon dioxide (CO\n                    <jats:sub>2<\/jats:sub>\n                    ) laser\u2010assisted deep sclerectomy surgery (CLASS) and trabeculectomy (Trab) for treatment of primary open\u2010angle glaucoma (POAG).\n                    <jats:italic>Methods<\/jats:italic>\n                    . In this retrospective and comparative study, 77 eyes of 62 patients with POAG were studied and divided into the CLASS and Trab groups. The best\u2010corrected visual acuity (BCVA), intraocular pressure (IOP), number of medications, surgical success rate, and complications were analyzed.\n                    <jats:italic>Results<\/jats:italic>\n                    . The mean follow\u2010up periods were 27.89\u2009\u00b1\u20092.94 months and 26.11\u2009\u00b1\u20092.06 months in the CLASS and Trab groups, respectively. 30 eyes (24 patients) underwent CLASS and 47 eyes (38 patients) underwent Trab. The BCVA in the CLASS and Trab groups was recovered to baseline at postoperative 1 week and 1 month, respectively. At last follow\u2010up visits, a remarkable reduction in the IOP and number of medications was observed in both groups, and no significant difference was found in those between the two groups. The complete success rates were 51.7% and 47.7% in postoperative 24 months in the CLASS and Trab groups, respectively (\n                    <jats:italic>P<\/jats:italic>\n                    &gt; 0.05). There were higher rates of delayed anterior chamber formation (21.3%) and thin\u2010wall filtrating blebs (10.6%) in the Trab group. Meanwhile, the peripheral anterior synechiae were only observed in the CLASS group, and the ratio was 30%.\n                    <jats:italic>Conclusions<\/jats:italic>\n                    . CLASS is an effective and safe treatment modality for POAG, with fewer filtering bleb\u2010related complications and quicker visual recovery in the early postoperative stage than trabeculectomy. The efficacy of lowering intraocular pressure was similar for both procedures.\n                  <\/jats:p>","DOI":"10.1155\/2021\/6639583","type":"journal-article","created":{"date-parts":[[2021,2,11]],"date-time":"2021-02-11T04:38:56Z","timestamp":1613018336000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":8,"title":["CO\n                    <sub>2<\/sub>\n                    Laser\u2010Assisted Deep Sclerectomy Surgery Compared with Trabeculectomy in Primary Open\u2010Angle Glaucoma: Two\u2010Year Results"],"prefix":"10.1155","volume":"2021","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-3922-3263","authenticated-orcid":false,"given":"Hengli","family":"Zhang","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yizhen","family":"Tang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4997-5389","authenticated-orcid":false,"given":"Xiaowei","family":"Yan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1757-281X","authenticated-orcid":false,"given":"Lihua","family":"Ma","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5858-7831","authenticated-orcid":false,"given":"Yulei","family":"Geng","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0205-1835","authenticated-orcid":false,"given":"Fan","family":"Li","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9089-7143","authenticated-orcid":false,"given":"Guangxian","family":"Tang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2021,2,10]]},"reference":[{"key":"e_1_2_10_1_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.ophtha.2011.09.043"},{"key":"e_1_2_10_2_2","doi-asserted-by":"publisher","DOI":"10.1007\/s00417-017-3844-1"},{"key":"e_1_2_10_3_2","doi-asserted-by":"publisher","DOI":"10.1038\/eye.1990.54"},{"key":"e_1_2_10_4_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.ajo.2005.02.013"},{"key":"e_1_2_10_5_2","doi-asserted-by":"publisher","DOI":"10.1097\/ijg.0000000000000437"},{"key":"e_1_2_10_6_2","doi-asserted-by":"publisher","DOI":"10.1007\/s00417-006-0413-4"},{"key":"e_1_2_10_7_2","doi-asserted-by":"publisher","DOI":"10.1097\/ijg.0000000000000187"},{"key":"e_1_2_10_8_2","doi-asserted-by":"publisher","DOI":"10.1111\/aos.13718"},{"key":"e_1_2_10_9_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.ophtha.2015.10.053"},{"key":"e_1_2_10_10_2","doi-asserted-by":"publisher","DOI":"10.1097\/ijg.0000000000000297"},{"key":"e_1_2_10_11_2","volume-title":"Ultrasound Biomicroscopy of the Eye","author":"Pavlin C. 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