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To describe liver imaging reporting and data system (LI\u2010RADS) version 2018 and other MRI imaging features in intrahepatic mass\u2010forming cholangiocarcinoma (iCCA) in Chinese adults with vs. without chronic hepatitis B viral (HBV) infection. <jats:italic>Methods<\/jats:italic>. We retrospectively enrolled 89 patients with pathologically proven iCCA after multiphase imaging performed between 2004 and 2017 at a tertiary medical center in southern China. Based on whether patients had chronic HBV, iCCA was divided into two subgroups: HBV\u2010positive (<jats:italic>n<\/jats:italic>\u2009=\u200950 patients, including 9 with cirrhosis) vs. HBV\u2010negative (<jats:italic>n<\/jats:italic>\u2009=\u200939 patients, including 14 with hepatolithiasis and 25 with no identifiable risk factor for iCCA; none had cirrhosis). Two independent abdominal radiologists in consensus reviewed the largest mass in each patient to assign LI\u2010RADS v2018 features; they also scored each observation\u2019s shape and location. Imaging features were compared using chi\u2010square or Fisher\u2019s exact tests. <jats:italic>Results<\/jats:italic>. Most iCCAs in HBV\u2010positive (88% (44\/50)) and HBV\u2010negative (97% (38\/39)) patients had at least one LR\u2010M feature. Compared to iCCAs in HBV\u2010negative patients, iCCAs in HBV\u2010positive patients were more likely to have at least one major feature of HCC (46% (23\/50) vs. 8% (3\/39), <jats:italic>P<\/jats:italic>\u2009&lt;\u20090.001) and more likely to be smooth (42% (21\/50) vs. 10% (4\/39), <jats:italic>P<\/jats:italic>\u2009=\u20090.001). Six of 50 (12%) iCCAs in HBV\u2010positive patients and 1\/39 (3%) iCCAs in HBV\u2010negative patients had at least one major feature of HCC without any LR\u2010M feature. <jats:italic>Conclusions<\/jats:italic>. In this retrospective single\u2010center study in Chinese adults, iCCAs in HBV\u2010positive patients were more likely to resemble HCCs than iCCAs in HBV\u2010negative patients.<\/jats:p>","DOI":"10.1155\/2021\/6639600","type":"journal-article","created":{"date-parts":[[2021,3,4]],"date-time":"2021-03-04T22:50:07Z","timestamp":1614898207000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":8,"title":["Liver Imaging and Data System (LI\u2010RADS) Version 2018 and Other Imaging Features in Intrahepatic Cholangiocarcinoma in Chinese Adults with vs. without Chronic Hepatitis B Viral 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