{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,11,7]],"date-time":"2025-11-07T00:55:27Z","timestamp":1762476927675,"version":"build-2065373602"},"reference-count":25,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2021,4,17]],"date-time":"2021-04-17T00:00:00Z","timestamp":1618617600000},"content-version":"vor","delay-in-days":106,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Case Reports in Dentistry"],"published-print":{"date-parts":[[2021,1]]},"abstract":"<jats:p>Recurrent aphthous stomatitis is an ulcerative disease of the oral cavity and can occur in isolation or as a manifestation of many systemic diseases. It is a quite common entity and may hence often be overlooked as an isolated lesion. Gilbert\u2019s syndrome is a genetic disorder where a deficiency of an enzyme associated with the conjugation of bilirubin results in unconjugated hyperbilirubinemia. The disease is generally asymptomatic and is aggravated by certain trigger factors. No associated oral manifestations are known. In this case report, we discuss the concomitant presence of recurrent aphthous stomatitis in a patient of Gilbert\u2019s syndrome. The presence of such recurrent stomatitis may represent as an oral manifestation of Gilbert\u2019s syndrome. Early identification of these entities may improve the overall quality of life of the patient.<\/jats:p>","DOI":"10.1155\/2021\/6648729","type":"journal-article","created":{"date-parts":[[2021,4,17]],"date-time":"2021-04-17T14:20:16Z","timestamp":1618669216000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":7,"title":["Occurrence of Recurrent Aphthous Stomatitis (RAS) as a Rare Oral Manifestation in a Patient with Gilbert\u2019s Syndrome"],"prefix":"10.1155","volume":"2021","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-8329-3205","authenticated-orcid":false,"given":"Artak","family":"Heboyan","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Anna","family":"Avetisyan","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9083-5188","authenticated-orcid":false,"given":"Hans Erling","family":"Skallevold","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3854-667X","authenticated-orcid":false,"given":"Dinesh","family":"Rokaya","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6673-9236","authenticated-orcid":false,"given":"Vinay","family":"Marla","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Anna","family":"Vardanyan","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2021,4,17]]},"reference":[{"key":"e_1_2_7_1_2","doi-asserted-by":"publisher","DOI":"10.4103\/0973-029X.86669"},{"key":"e_1_2_7_2_2","doi-asserted-by":"publisher","DOI":"10.1590\/abd1806-4841.20186228"},{"key":"e_1_2_7_3_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.adengl.2019.09.006"},{"key":"e_1_2_7_4_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-0714.1978.tb01601.x"},{"key":"e_1_2_7_5_2","first-page":"26","article-title":"Recurrent aphthous stomatitis: a review","volume":"10","author":"Edgar N. R.","year":"2017","journal-title":"The Journal of Clinical and Aesthetic Dermatology"},{"key":"e_1_2_7_6_2","first-page":"74","article-title":"Guideline for the diagnosis and treatment of recurrent aphthous stomatitis for dental practitioners","volume":"7","author":"Tarakji B.","year":"2015","journal-title":"Journal of International Oral Health"},{"key":"e_1_2_7_7_2","doi-asserted-by":"publisher","DOI":"10.3892\/br.2019.1221"},{"key":"e_1_2_7_8_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2036.2005.02333.x"},{"key":"e_1_2_7_9_2","doi-asserted-by":"publisher","DOI":"10.3329\/bjms.v19i2.45018"},{"key":"e_1_2_7_10_2","doi-asserted-by":"publisher","DOI":"10.1080\/13102818.2019.1649987"},{"key":"e_1_2_7_11_2","doi-asserted-by":"publisher","DOI":"10.1136\/bmj.2.5969.480"},{"key":"e_1_2_7_12_2","doi-asserted-by":"publisher","DOI":"10.1186\/s12876-019-0931-2"},{"key":"e_1_2_7_13_2","first-page":"95","article-title":"Recurrent aphthous stomatitis","volume":"31","author":"Ship J. A.","year":"2000","journal-title":"Quintessence International"},{"key":"e_1_2_7_14_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.cden.2013.12.002"},{"key":"e_1_2_7_15_2","doi-asserted-by":"publisher","DOI":"10.1111\/jop.12298"},{"key":"e_1_2_7_16_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1601-0825.2011.01840.x"},{"key":"e_1_2_7_17_2","doi-asserted-by":"publisher","DOI":"10.1136\/bcr-2013-009962"},{"key":"e_1_2_7_18_2","doi-asserted-by":"publisher","DOI":"10.4103\/0970-9185.81836"},{"key":"e_1_2_7_19_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.biocel.2013.09.014"},{"key":"e_1_2_7_20_2","doi-asserted-by":"publisher","DOI":"10.1007\/BF02814488"},{"key":"e_1_2_7_21_2","doi-asserted-by":"publisher","DOI":"10.1074\/jbc.274.16.10852"},{"key":"e_1_2_7_22_2","doi-asserted-by":"publisher","DOI":"10.3389\/fimmu.2018.02171"},{"key":"e_1_2_7_23_2","doi-asserted-by":"publisher","DOI":"10.1097\/01.mph.0000243656.25938.7b"},{"key":"e_1_2_7_24_2","doi-asserted-by":"publisher","DOI":"10.1007\/s12105-018-0977-4"},{"key":"e_1_2_7_25_2","first-page":"70","article-title":"Two-layer adhesive film Diplen-denta C--a new compound containing polymer base and active component Solcoseryl","volume":"86","author":"Abakarova D. S.","year":"2007","journal-title":"Stomatologiia (Mosk)"}],"container-title":["Case Reports in Dentistry"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/downloads.hindawi.com\/journals\/crid\/2021\/6648729.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/downloads.hindawi.com\/journals\/crid\/2021\/6648729.xml","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1155\/2021\/6648729","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,11,7]],"date-time":"2025-11-07T00:51:46Z","timestamp":1762476706000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1155\/2021\/6648729"}},"subtitle":[],"editor":[{"given":"Alberto","family":"Delbem","sequence":"additional","affiliation":[],"role":[{"role":"editor","vocabulary":"crossref"}]}],"short-title":[],"issued":{"date-parts":[[2021,1]]},"references-count":25,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2021,1]]}},"alternative-id":["10.1155\/2021\/6648729"],"URL":"https:\/\/doi.org\/10.1155\/2021\/6648729","archive":["Portico"],"relation":{},"ISSN":["2090-6447","2090-6455"],"issn-type":[{"type":"print","value":"2090-6447"},{"type":"electronic","value":"2090-6455"}],"subject":[],"published":{"date-parts":[[2021,1]]},"assertion":[{"value":"2020-12-11","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2021-04-07","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2021-04-17","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}],"article-number":"6648729"}}