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Accordingly, we performed an analysis to accurately assess the relationship between serum IL\u201037 cytokine levels and disease activity of RA. Subgroup analysis and sensitivity analysis were applied to explore the sources of heterogeneity. Correlation coefficient (<jats:italic>r<\/jats:italic>) was utilized to evaluate the relationship between IL\u201037 and disease activity of RA patients. Ten studies were included into the research. Functional analysis revealed elevated serum IL\u201037 concentrations in RA patients (SMD = 1.61, <jats:italic>P<\/jats:italic> &lt; 0.00001). The relationship between serum IL\u201037 levels and disease activity was statistically significant (C\u2010reactive protein: <jats:italic>r<\/jats:italic> = 1.47, <jats:italic>P<\/jats:italic> = 0.0002; erythrocyte sedimentation rate: <jats:italic>r<\/jats:italic> = 1.55, <jats:italic>P<\/jats:italic> &lt; 0.00001; rheumatoid factor: <jats:italic>r<\/jats:italic> = 1.40, <jats:italic>P<\/jats:italic> = 0.004; tumor necrosis factor\u2043<jats:italic>\u03b1<\/jats:italic>: <jats:italic>r<\/jats:italic> = 1.64, <jats:italic>P<\/jats:italic> = 0.0003; Disease Activity Score for 28 joints: <jats:italic>r<\/jats:italic> = 1.63, <jats:italic>P<\/jats:italic> &lt; 0.00001; tender joint count: <jats:italic>r<\/jats:italic> = 1.48, <jats:italic>P<\/jats:italic> &lt; 0.00001; and swollen joint count: <jats:italic>r<\/jats:italic> = 1.52, <jats:italic>P<\/jats:italic> = 0.0003), but anti\u2010CCP was not significant (anti\u2010CCP: <jats:italic>r<\/jats:italic> = 0.98, <jats:italic>P<\/jats:italic> = 0.72). In summary, these data are suggesting that the elevated serum level of IL\u201037 in RA is positively correlated with the disease activity of RA, suggesting a role for IL\u201037in the pathogenesis of RA.<\/jats:p>","DOI":"10.1155\/2021\/6653439","type":"journal-article","created":{"date-parts":[[2021,2,8]],"date-time":"2021-02-08T23:27:22Z","timestamp":1612826842000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":11,"title":["[Retracted] Serum IL\u201037 Level Is Associated with Rheumatoid Arthritis and Disease Activity: A Meta\u2010Analysis"],"prefix":"10.1155","volume":"2021","author":[{"given":"Shengnan","family":"Cao","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Haojun","family":"Shi","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Guodong","family":"Sun","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yuanzhen","family":"Chen","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Guangjian","family":"Hou","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5774-2871","authenticated-orcid":false,"given":"Dandan","family":"Wang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9305-5438","authenticated-orcid":false,"given":"Bin","family":"Shi","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2021,2,8]]},"reference":[{"key":"e_1_2_8_1_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jbspin.2016.07.007"},{"key":"e_1_2_8_2_2","doi-asserted-by":"publisher","DOI":"10.1111\/imm.12660"},{"key":"e_1_2_8_3_2","doi-asserted-by":"publisher","DOI":"10.1080\/08916934.2018.1551373"},{"key":"e_1_2_8_4_2","doi-asserted-by":"publisher","DOI":"10.1080\/14397595.2016.1266071"},{"key":"e_1_2_8_5_2","doi-asserted-by":"publisher","DOI":"10.1002\/art.39953"},{"key":"e_1_2_8_6_2","doi-asserted-by":"publisher","DOI":"10.2147\/DDDT.S91374"},{"key":"e_1_2_8_7_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.autrev.2015.08.006"},{"key":"e_1_2_8_8_2","doi-asserted-by":"publisher","DOI":"10.1684\/ecn.2011.0288"},{"key":"e_1_2_8_9_2","doi-asserted-by":"publisher","DOI":"10.1186\/s12967-015-0394-3"},{"key":"e_1_2_8_10_2","doi-asserted-by":"publisher","DOI":"10.1186\/1479-5876-12-69"},{"key":"e_1_2_8_11_2","doi-asserted-by":"publisher","DOI":"10.22034\/IJI.2018.39386"},{"key":"e_1_2_8_12_2","doi-asserted-by":"publisher","DOI":"10.1007\/s10654-010-9491-z"},{"key":"e_1_2_8_13_2","doi-asserted-by":"publisher","DOI":"10.1186\/1471-2288-14-135"},{"key":"e_1_2_8_14_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.cca.2014.08.040"},{"key":"e_1_2_8_15_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.cyto.2018.07.027"},{"key":"e_1_2_8_16_2","doi-asserted-by":"publisher","DOI":"10.12659\/MSM.909254"},{"key":"e_1_2_8_17_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.cyto.2015.06.005"},{"key":"e_1_2_8_18_2","doi-asserted-by":"publisher","DOI":"10.1111\/apm.12467"},{"key":"e_1_2_8_19_2","doi-asserted-by":"publisher","DOI":"10.1142\/S0192415X14500189"},{"key":"e_1_2_8_20_2","first-page":"23","article-title":"Expression of TLR4 in peripheral blood of patients with 274 rheumatoid arthritis and its correlation with IL-37 level","volume":"2","author":"Wan L. 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