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These included thrombotic thrombocytopenic purpura (TTP), right leg deep vein thrombosis (DVT), and eventually constitutional symptoms, arthralgia, diffuse lymphadenopathy, pancytopenia, skin rash, pericarditis, and glomerulonephritis. Serologic tests and renal pathology uncovered a diagnosis of systemic lupus erythematosus (SLE), and immunosuppressive therapy was initiated. Soon after, the patient developed striking cytomegalovirus (CMV) viremia, requiring prolonged antiviral therapy and reduction of immunosuppression. Finally, an acute embolic stroke complicated the disease course. Prompt interventions allowed an excellent clinical outcome.<\/jats:p>","DOI":"10.1155\/2021\/6654748","type":"journal-article","created":{"date-parts":[[2021,1,5]],"date-time":"2021-01-05T20:15:57Z","timestamp":1609877757000},"page":"1-5","source":"Crossref","is-referenced-by-count":0,"title":["From TTP to Glomerulonephritis: A Lifetime of Lupus"],"prefix":"10.1155","volume":"2021","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-3540-0341","authenticated-orcid":true,"given":"Fadi","family":"Kharouf","sequence":"first","affiliation":[{"name":"Department of Medicine, Hebrew University-Hadassah Medical Center, Jerusalem, Israel"},{"name":"Rheumatology Unit, Hebrew University-Hadassah Medical Center, Jerusalem, Israel"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sigal","family":"Shahar","sequence":"additional","affiliation":[{"name":"Department of Medicine, Hebrew University-Hadassah Medical Center, Jerusalem, Israel"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yoav","family":"Hershkovitz","sequence":"additional","affiliation":[{"name":"Department of Medicine, Hebrew University-Hadassah Medical Center, Jerusalem, Israel"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Alaa","family":"Shaheen","sequence":"additional","affiliation":[{"name":"Department of Medicine, Hebrew University-Hadassah Medical Center, Jerusalem, Israel"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Areej","family":"Bayatra","sequence":"additional","affiliation":[{"name":"Department of Medicine, Hebrew University-Hadassah Medical Center, Jerusalem, Israel"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6051-8192","authenticated-orcid":true,"given":"Asa","family":"Kessler","sequence":"additional","affiliation":[{"name":"Department of Medicine, Hebrew University-Hadassah Medical Center, Jerusalem, Israel"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yuval","family":"Ishay","sequence":"additional","affiliation":[{"name":"Department of Medicine, Hebrew University-Hadassah Medical Center, Jerusalem, Israel"},{"name":"Gastroenterology Unit, Hebrew University-Hadassah Medical Center, Jerusalem, Israel"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","reference":[{"key":"1","doi-asserted-by":"publisher","DOI":"10.1136\/rmdopen-2018-000793"},{"key":"2","volume-title":"Infections in Systemic Lupus Erythematosus","author":"E. 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