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To assess the impact of incisor molar hypomineralization (MIH) on oral health-related quality of life (OHRQoL) according to the perception of students and their parents\/caregivers. Materials and Methods. This is a cross-sectional population-based study with 463 Brazilian students aged 11\u201314 years. OHRQoL was measured using the Child Perceptions Questionnaire (B-CPQ11-14ISF: 16) applied to students and the short version of the Parental-Caregiver Perceptions Questionnaire (B-P-CPQ) applied to parents\/caregivers. The diagnosis of MIH followed the European Academy of Paediatric Dentistry criteria modified in 2019. Caries experience (ICDAS II), malocclusion (DAI), and socioeconomic and demographic factors were assessed as confounding factors for impact on OHRQoL. Cluster analysis was carried out to dichotomize the negative impact into greater and lesser impact. The chi-square test and Poisson regression were performed (<jats:inline-formula>\n                     <a:math xmlns:a=\"http:\/\/www.w3.org\/1998\/Math\/MathML\" id=\"M1\">\n                        <a:mi>p<\/a:mi>\n                        <a:mo>&lt;<\/a:mo>\n                        <a:mn>0.05<\/a:mn>\n                     <\/a:math>\n                  <\/jats:inline-formula>) to verify associations between quality of life and MIH, adjusted for confounding variables. Results. The prevalence of MIH was 10.8%. Multivariate regression demonstrated that caries experience was the only oral disease that impacted OHRQoL according to students\u2019 self-perception in the functional limitation domain (PR\u2009=\u20091.82; 95% CI\u2009=\u20091.20\u20132.77) and in the total questionnaire score (PR\u2009=\u20091.59; 95% CI\u2009=\u20091.00\u20132.51). However, according to the perception of parents\/caregivers, in addition to caries experience, which affected OHRQoL in the oral symptoms (PR\u2009=\u20093.57; 95% CI\u2009=\u20091.71\u20137.414) and emotional well-being domains (PR\u2009=\u20091.71; 95% CI\u2009=\u20091.08\u20132.69), as well as in the total B-P-CPQ score (PR\u2009=\u20091.67; 95% CI\u2009=\u20091.01\u20132.76), malocclusion also affected OHRQoL in the social well-being domain (PR\u2009=\u20091.50; 95% CI\u2009=\u20091.07\u20132.10) and in the total questionnaire score (PR\u2009=\u20091.54; 95% CI\u2009=\u20091.11\u20132.15). Conclusion. According to students and their parents\/caregivers\u2019 perception, incisor molar hypomineralization did not influence OHRQoL of the studied sample.<\/jats:p>","DOI":"10.1155\/2021\/6655771","type":"journal-article","created":{"date-parts":[[2021,3,4]],"date-time":"2021-03-04T02:05:06Z","timestamp":1614823506000},"page":"1-14","source":"Crossref","is-referenced-by-count":15,"title":["Incisor Molar Hypomineralization and Quality of Life: A Population-Based Study with Brazilian Schoolchildren"],"prefix":"10.1155","volume":"2021","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-6431-7857","authenticated-orcid":true,"given":"Liege Helena","family":"Freitas Fernandes","sequence":"first","affiliation":[{"name":"Department of Dentistry, State University of Para\u00edba, Campina Grande, Para\u00edba, Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6621-1834","authenticated-orcid":true,"given":"Isla Camila C.","family":"Laureano","sequence":"additional","affiliation":[{"name":"Department of Dentistry, State University of Para\u00edba, Campina Grande, Para\u00edba, Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4077-6706","authenticated-orcid":true,"given":"Lunna","family":"Farias","sequence":"additional","affiliation":[{"name":"Department of Dentistry, State University of Para\u00edba, Campina Grande, Para\u00edba, Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nat\u00e1lia M.","family":"Andrade","sequence":"additional","affiliation":[{"name":"Department of Dentistry, State University of Para\u00edba, Campina Grande, Para\u00edba, Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4237-0184","authenticated-orcid":true,"given":"Franklin Delano","family":"Soares Forte","sequence":"additional","affiliation":[{"name":"Department of Clinical and Social Dentistry, Federal University of Para\u00edba, Jo\u00e3o Pessoa, Para\u00edba, Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8718-8311","authenticated-orcid":true,"given":"Catarina Ribeiro","family":"Barros Alencar","sequence":"additional","affiliation":[{"name":"Academic Unit of Biological Sciences, Faculty of Dentistry, Federal University of Campina Grande, Patos, Para\u00edba, Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3572-3332","authenticated-orcid":true,"given":"Alessandro Leite","family":"Cavalcanti","sequence":"additional","affiliation":[{"name":"Department of Dentistry, State University of Para\u00edba, Campina Grande, Para\u00edba, Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","reference":[{"key":"1","first-page":"38","article-title":"Oral health-related quality of life in Colombian children with molar-incisor hypomineralization","volume":"31","author":"L. 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